T-Cell
CD4+ T cell effects on CD8+ T cell location defined using bioluminescence.
... CD4+ T cells influence the biodistribution of CD8+ T ...CD8+ T cells were double- transgenic, expressing both an antigen-specific T cell receptor that recognizes an ovalbumin-derived ...
10
A novel regulatory T cell population in the gut.
... of T cells (the T cell receptor, or TCR), whose signaling prompts secretion of proteins called cyto- kines that coordinate the immune system’s efforts to fight off the ...
2
A logical model provides insights into T cell receptor signaling.
... primary T cells and excluded data obtained from knockout mice showing alterations of thymic development, we did not include ...Logical T Cell Signaling Model (Figure 1) for the Early Events Scenario ...
11
Regulation of T cell responses by Heme Oxygenase-1
... and T cells, the main mediators of adaptive responses, to recognize and distinguish subtle differences among ...by T and B cells, they are referred to as T-cell and B-cell receptors, ...
43
The Role Of miRNAs In CD8+ T Cell Differentation
... miRNA-deficient T cells are still able to function, the approaches using T cell-specific miRNA-deficient mice, clearly demonstrated that miRNAs are implicated in various aspects of T ...
87
Strategies for T-cell reconstruction : insights from human clinical models
... the T cell areas of secondary lymphoid organs where naïve T lymphocytes encounter antigen-loaded ...DC. T lymphocytes recognize antigen through the interaction of their TCR with foreign ...
224
Strong HIV-1-Specific T Cell Responses in HIV-1-Exposed Uninfected Infants and Neonates Revealed after Regulatory T Cell Removal
... Our objective was to measure HIV-1-specific T cell immune responses at the time of delivery and within the first year of life. Furthermore, we wanted to establish whether these responses were sustained and ...
10
Helper T cell epitope-mapping reveals MHC-peptide binding affinities that correlate with T helper cell responses to pneumococcal surface protein A.
... S. pneumonia Strain EF3030 Growth and Challenge S. pneumonia capsular strain EF3030 was among the human isolates of capsular group 19 that were previously examined and found to be relatively non-invasive in mice [72]. ...
16
HIV-1 AND CD4 T CELL VESICLE EXOCYTOSIS
... CD4 T cells, eludes the CD4 T cell immune response, and finally, elicits an inflammatory immune response that ultimately leads to CD4 T cell exhaustion and unresponsive- ...of ...
5
CD8+ T cell control of HIV--a known unknown.
... CD8+ T cell depletion leads to activation of CD4+ T cells; since SIV preferentially infects acti- vated cells, the infected CD4+ T cells are dying, but these dying cells are being replaced ...
3
Follicular helper T cell in immunity and autoimmunity
... [encoding T-box expressed in T cells (T-bet)] and Rorc [encoding retinoic acid-related orphan receptor gt (RORgt)] or by direct binding to GATA-bind protein 3 (GATA3) ...in T cells in vitro, ...
11
Linking inflammation to natural killer T cell activation.
... different cell types, including dendritic cells, macrophag- es, neutrophils, and natural killer ...and T lymphocytes, which survey billions of antigens via cell surface receptors that undergo somatic ...
5
A TNM Staging System for Nasal NK/T-Cell Lymphoma.
... NK/T-cell lymphoma (NKTCL) has been generally classified into nasal NKTCL (N-NKTCL) involving the upper aerodigestive tract (UAT) and extranasal NKTCL (E-NKTCL) including primary tumors outside the UAT [1]. ...
17
Caerulomycin A suppresses immunity by inhibiting T cell activity.
... CD4 T cells can be subdivided into Th1 and Th2 ...for cell-mediated ...activated T cells. After receiving antigen stimulation, T cells undergo clonal ...the T cell proliferation ...
10
Glycans as Key Checkpoints of T Cell Activity and Function
... a cell surface inhibitory T cell receptor responsible for immune-inhibitory responses associated with the so-called “T cell exhaustion” ...this cell surface receptor, as well as ...
13
Non Hodgkin T cell lymphoma: an atypical clinical presentation
... positive T- cells, some of which had CD8 positivity (Figures 3, 4 and ...of T-cell lymphoma with cytotoxic expression (Figure ...of T-cell receptors rearrange- ment by PCR confirmed the ...
4
iNKT cells suppress the CD8+ T cell response to a murine Burkitt's-like B cell lymphoma.
... T cell responses is consistent with these observations, as many tumor-associated antigens are self ...B cell lymphoma used in the current study arose from an autoreactive B cell [16], it may ...
11
Unveiling thymic epithelial cell ontogeny: a roadmap to study the microenvironment for T-cell generation and tolerance
... tiate, which expands and replaces (or dilutes) Il7 YFP+ TECs. The establishment of medullary microenvironments involves the hier- archical, but concerted, participation of TNFRSF RANK, LTbR, and CD40 molecules (9). Our ...
160
Activated T cell trans-endothelial migration relies on myosin-IIA contractility for squeezing the cell nucleus through endothelial cell barriers.
... activated T cells also rely on MyoIIA for TEM and homing to sites of ...the T cell compartment, this might generate useful forms of ...of T cells could reduce reactivity for rare antigens, ...
13
To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
... During T-cell immune responses, naive T cells are activated by stimuli through TCR in the company of co-stimulation signals, and undergo multiple rounds of proliferation before entering the ...
13