+ T cells
Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naive T cells into cytokine-producing mature T cells.
... T cells have been classified as belonging to the Th1 or Th2 subsets according to the production of defining cytokines such as IFN-c and ...regulatory T cells shifted the simple concept of the ...
5
A molecular assay for sensitive detection of pathogen-specific T-cells.
... of cells and is gaining popularity in vaccine immunology ...pathogen-specific T cells and apply this to the detection of MTB infection, as an example of its ...
10
Regulation and gene expression profiling of NKG2D positive human cytomegalovirus-primed CD4+ T-cells.
... T-cells using TRIzol reagent (Invitrogen). Microarray analysis was performed by the RH Microarray Center (Center for Genomic Medicine, Copenhagen University Hospital, Denmark) using a Human Gene 1.0 ST ...
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High efficiency of antiviral CD4(+) killer T cells.
... T cells were subsequently sorted on a FACS Aria (BD Biosciences) to ...SMARTA cells isolated and analyzed with Affymetrix M430 ...SMARTA cells into 3 ...
12
Eosinophils from Murine Lamina Propria Induce Differentiation of Naive T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid.
... Treg cells. Thus, naive T cells were again co-cultured with LP or PB eosinophils, with or without antibody neutralization of ...Treg cells conversion, we added increasing doses of recombinant ...
13
A convenient model of severe, high incidence autoimmune gastritis caused by polyclonal effector T cells and without perturbation of regulatory T cells.
... Treg cells was detected in the paragastric lymph node of gastritic mice, and a significantly higher percentage of Treg cells was found in the stomach of gastritic mice compared to normal mice, Treg ...
8
High epitope expression levels increase competition between T cells.
... where T cells corresponded to the predators and the epitope- presenting APCs corresponded to the ...independent T cell interaction sites on APCs that are either free or engaged in an interaction with ...
11
Photo(chemo)therapy reduces circulating Th17 cells and restores circulating regulatory T cells in psoriasis.
... T cells were significantly reduced in the epidermis and dermis of lesional ...positive T cells were significantly decreased after only 1 day in the sun and in vitro- stimulated PBMCs showed a ...
9
Direct infection of dendritic cells during chronic viral infection suppresses antiviral T cell proliferation and induces IL-10 expression in CD4 T cells.
... dendritic cells (DCs) are important for viral ...CD4 T cells, which we identify as the most frequent IL-10-expressing cell type in chronic LCMV ...CD4 T cells, and suppress ...
10
Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice.
... cd T cells Changes in the cd T cell subset have been documented in NOD mice [23] as well as in human T1D [24–26], In addition cd T cells have been shown to play an important role in ...
12
To investigate the necessity of STRA6 upregulation in T cells during T cell immune responses.
... for T-cell activation, differentiation and ...WT T cells were similar in terms of TCR-stimulated proliferation in vitro and homeostatic expansion in ...CD4 cells differentiated in vitro into ...
13
The role of CD8+ T cells during allograft rejection
... In a model of aorta transplant in mice (36) it was shown that anti-CD40L and anti- CD4 therapy could delay but not prevent the graft from developing transplant arterioscle- rosis. Anti-CD8 antibody caused a decrease in ...
12
Phenotypic and functional aspects of CD8 + T cells in atopy: from populations to cells
... CD8+ T cell subpopulations showed similar proliferation capacity in atopic and non-atopic individuals, and did not show suppressor ...blood T cells do not share the same cellular environment as their ...
132
B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
... memory T cells. Previously, we have shown that B cells capture plasmid DNA-Hsp65 and thereby modulate the formation of CD8 + memory T cells after ...B cells act as part of the ...
6
Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells.
... HEK293 cells transfected with TLR2 or TLR4 and a reporter gene IL-8 Figure ...Th1 cells and diverts LPS-induced inhibition of IL-10 production by the GAD65-specific ...GAD65-specific cells were ...
7
Exchange of cytosolic content between T cells and tumor cells activates CD4 T cells and impedes cancer growth.
... tumor cells by visualization of the contact ...the T cell into the tumor cell which emerged at the highest magnification to be enabled by gaps in the cell membrane of both partners (Figure 1E ...L23 ...
14
Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter.
... derived T cells respond to ubiquitous environmental antigens by high ...putative T regulatory cell (Treg) compartment or even expansion of the Treg compartment ...
8
T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells.
... effector T cells, in particular master transcription regulators T-bet and ...In T cells, T-bet and Eomes are regulated by cytokines with divergent functions and therefore have ...
10
Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy.
... pos T cells were negatively selected using mAbs directed against CD8 (RPA-T8), CD14 (M5E2), CD16 (3G8), CD19 (4G7), CD33 ...pos T cell fraction. CD25 high Treg and CD25 neg conventional T ...
13
Targeting c-MYC with T-cells.
... splenic T-cells were ...between cells restimulated with c-MYC protein or peptide pool, whereas T-cells from naïve or OVA- immunized control mice revealed only background secretion ...
14