Th1 cells
Characterization of T cell receptors of Th1 cells infiltrating inflamed skin of a novel murine model of palladium-induced metal allergy.
... T cells in the pathogenesis of metal allergy has not been ...T cells by multiple injections of palladium (Pd) plus lipopolysaccharide into the ...T cells in terms of phenotypic markers, T cell ...
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IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals.
... that Th1 priming and the early effector phase of the Th1 response are unaffected by lack of IL-27 signalling during ...the Th1 response fails to reach a plateau after day 9 of infection leading to ...
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Differential Impact of LPG-and PG-Deficient Leishmania major Mutants on the Immune Response of Human Dendritic Cells.
... are among the major cell sources of IL12, whose bioactive secretion is dependent upon the covalent linkage between the p40 (IL12B) and p35 (IL12A) subunits [18]. The ability of Leish- mania to selectively suppress IL12 ...
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An approach to control relapse of inflammatory lesions after discontinuation of primary therapy.
... under Th1, Th17 or regulatory T cell polarizing conditions in vitro for 5 ...incubation, cells were stained for measuring the production of cytokines and transcription factor Foxp3 by intra cellular/nuclear ...
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Myocardial chemokine expression and intensity of myocarditis in Chagas cardiomyopathy are controlled by polymorphisms in CXCL9 and CXCL10.
... mononuclear cells in CCC ...polarized Th1 T cells to sites of chronic inflammation [41], and most of them are also IFN-c-inducible chemokines ...of Th1 cells in CCC heart ...endothelial ...
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Interplay of Cytokines and Chemokines in the Pathogenesis of Systemic Lupus Erythematosus
... effector cells to sites of inflammation and regulation of differential recruitment of T helper (Th1 and Th2) lymphocytes (Premack and Schall, 1996; Sallusto, ...a Th1 chemokine and has an important ...
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Short communication Increased type 1 chemokine expression in experimental Chagas disease correlates with cardiac pathology in Beagle dogs
... Chemokines and chemokine receptors interaction have presented important role in leuko- cyte migration to specific immune reaction sites. Recently, it has been reported that chemokine receptors CXC (CXCR3) and CC (CCR5) ...
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Ribavirin exerts differential effects on functions of Cd4+ Th1, Th2, and regulatory T cell clones in hepatitis C.
... + TH1, TH2 and regulatory T cell (Treg) clones, ...of TH1 and TH2 effector cells by Treg ...effector cells and increased production of IFN-gamma in TH1 clones, but had only little ...
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Rev. Soc. Bras. Med. Trop. vol.45 número6
... of Th1 and Th2 cells through the expression of CXCR3 and CCR4 chemokine receptors, ...CXCR3+Th1 cells compared to infected individuals ...Th2 cells in atopic dermaiis paients, while the ...
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Role of Th1 and Th2 cells in autoimmune demyelinating disease
... (i.e., Th1 cells) are detectable in brain tissue early in the development of disease ...effector cells that are capable of transferring disease appear to be IFN- γ - and tumor necro- sis factor-ß ...
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STUDY OF IRRADIATED BOTHROPSTOXIN-1 WITH
... Th2 cells that participate in humoral immunity, helping the antibody production by B lymphocytes ...of Th1 cell response, involved in cellular immunity (11). Th1 cells influence on IgG2a ...
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The low efficiency of dendritic cells and macrophages from mice susceptible to Paracoccidioides brasiliensis in inducing a Th1 response
... B cells (19), vascular endothelial cells, activated T cells (20), L cell fibroblasts transfected with MHC class II genes (21) and dendritic cells ...B cells and dendritic cells. ...
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Protein kinase C θ regulates the phenotype of murine CD4+ Th17 cells.
... T cells during the Th17 priming, what corresponds with the observed enhancement of IFN-c ...in cells allows continuous IFN-c ...human cells showed that PKCh influences the transcription of miRNA ...
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Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predispose the liver to inflammation.
... An additional finding of our study is that pDCs are significantly decreased in the late phase of colitis in the chronic models. Hepatic pDCs plays an important role in maintaining liver homeostasis [9,10,14], so not only ...
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Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... BMDC and BMM do not show an inhibition of IL-12 expression but rather an enhancement. We obtained similar results using CA074Me, the methyl ester form of CA074. Upon uptake by the cell, CA074Me is hydrolyzed to CA074, ...
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Calcitonin gene-related peptide regulates type IV hypersensitivity through dendritic cell functions.
... Dendritic cells (DCs) play essential roles in both innate and adaptive immune ...suppressed Th1 cell differentiation via inhibition of IL-12 production in DCs using an in vitro co-culture system and an in ...
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Impact of IL-10 and SIRT2 in the protective immune response to Mycobacterium tuberculosis and Listeria monocytogenes infections
... Our results showed that high amounts of IL-10 produced early after aerosol M. tuberculosis infection, namely between day 3 before challenge and day 5 post-infection, did not impact the outcome of infection. We also ...
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Bacillus subtilis KCTC 11782BP-produced alginate oligosaccharide effectively suppresses asthma via T-helper cell type 2-related cytokines.
... via a dose-dependent manner, and IL-5 and IL-6 mRNA levels were completely blocked by treatment with 400 mg/kg/day AO. Furthermore, AO dose-dependently suppressed the expres- sion of IL-5 and IL-13. Although treatments ...
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The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling.
... Unexpectedly, the adjuvant effect of DDA/TDB, even though dependent on IL-1/IL-1R1, was less strongly reliant on the inflammasome adaptor molecule ASC. Here again, DDA/TDB differed in the requirements for induction of ...
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UNIVERSIDADE FEDERAL DE UBERLÂNDIA INSTITUTO DE GENÉTICA E BIOQUÍMICA PÓS-GRADUAÇÃO EM GENÉTICA E BIOQUÍMICA PAPILOMAVÍRUS HUMANO: NOVAS ABORDAGENS EPIDEMIOLÓGICAS, DIAGNÓSTICAS E PERSPECTIVAS VACINAIS
... Human papillomavirus (HPV) infection is the most common sexually transmitted viral disease. More than 100 HPV types have been identified and approximately half of them have high tropism for epithelial cells and ...
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