Tubular cells
DPP-4 inhibitor attenuates toxic effects of indoxyl sulfate on kidney tubular cells.
... Indoxyl sulfate (IS), a metabolite of tryptophan, accelerates the progression of CKD. It is synthesized in the liver from indole and normally excreted into urine. As kidney impairment, IS accumu- lates in serum due to ...
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A polymeric nanomedicine diminishes inflammatory events in renal tubular cells.
... cultured tubular cells, QM56 was tested in an animal model of AKI that shares features with human AKI, such as tubular cell apoptosis and inflammation ...decreased tubular cell DNA ...
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Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.
... renal tubular cells has remained ...of tubular cells exposed to stress ...while cells became more resistant to these stresses by up-regulation of ...proximal tubular cells ...
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TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21.
... NFkB activation in fibroblasts [24]. However, no consequences of this activation were studied and it is unknown if the pathway is active in epithelial cells [24]. Indeed no targets of non-canonical NFkB by TWEAK ...
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Involvement of endoplasmic reticulum stress in albuminuria induced inflammasome activation in renal proximal tubular cells.
... Briefly, cells cultured on cover slips were washed twice with cold PBS and fixed with cold methanol/acetone (1:1) for 10 min at -20 ...the cells were blocked with 2% normal donkey serum in PBS buffer for 40 ...
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Endo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosin.
... proximal tubular cells after down-regulation of the CTNS gene with specific siRNA and confirmed the results in proximal tubular cells derived from patients with ...cystinosin-deficient ...
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Bioinspired polyethersulfone-based hollow fiber membranes as the scaffolds in renal assist device for protein-bound toxins removal from blood
... proximal tubular cells these scaffolding proteins are thought to generate cell polarity by forming connections with both tight junction complexes and transporter proteins and the signaling molecules ...the ...
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Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats.
... proximal tubular cells that contained numerous dysmorphic mitochondria, including swelling and disrupted cristae ...to tubular cell mitochondria was also investigated in vitro. HK2 cells were ...
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J. Bras. Nefrol. vol.38 número4
... 9. Andreucci M, Faga T, Russo D, Bertucci B, Tamburrini O, Pi- sani A, et al. Differential activation of signaling pathways by low-osmolar and iso-osmolar radiocontrast agents in human renal proximal tubular ...
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Nephrotoxicity Of Polymyxin B: Experimental Study In Cells And Implications For Nursing Practice
... In clinical pracice, AKI is convenionally known as acute tubular necrosis (ATN). Experimental studies have shown that the straight porion of the proximal tubule (S3 segment) is the most vulnerable to ischemic or ...
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J. Bras. Nefrol. vol.36 número1
... of cells in the S1 and S2 segments are responsible for 90% of total glucose ...proximal tubular cells, whereas glucose utilization is limited to the distal ...in cells of the distal nephron ...
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Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK)
... In gout, UrAc accumulation is associated with inlamma- tion. On the other hand, in the renal system, the mechanisms described for UrAc effects on proximal epithelial tubular cells include NF-kB, protein ...
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Bothrops leucurus venom induces in the isolated perfused kidney and cultured renal tubular epithelia
... renal tubular cells of the type MDCK (Madin–Darby Canine ...percentual tubular transport of sodium (%TNa þ ) at 120 min and of chloride (%TCl ) at 60 and 90 ...renal tubular cells gives ...
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Comparação dos efeitos de dexmedetomidina administrada em dois momentos diferentes para lesão de isquemia/reperfusão renal em ratos.
... No grupo IR, infiltrac¸ão de células mononucleares na área peritubular, especialmente na área cortical, perda de borda em escova das células do túbulo proximal, atrofia tubular, dilatac¸ão tubular e ...
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Evaluation of KIM-1 as an early biomarker of snakebite-induced AKI in mice
... Overall, AKI diagnosis has used creatinine levels as its biomarker. However, it is not a specific, sensible and early predictor of damage. Significant nephron damage is necessary to obtain an increase in plasma creatinine ...
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Proximal tubular hypertrophy and enlarged glomerular and proximal tubular urinary space in obese subjects with proteinuria.
... The obese and lean groups studied were similar as far as height, gender, proteinuria and serum albumin concentrations were concerned. Glomerular filtration rate was normal in the lean group and increased by 55% in the ...
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Retrospective review and systematic study of mammary tumors in dogs and characteristics of the extracellular matrix
... simple tubular adenocarcinomas, 3.91% were complex tubular adenocarcinomas, ...complex tubular adenocarcinomas: 38% presented desmoplasia, 57% cartilaginous metaplasia and 28% bone ...
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Ensaio de aplicabilidade in vitro do sistema dinâmico do quadril AF(DHS- AF).
... de permitir a troca do parafuso deslizante sem que, obrigatoria- mente, o cirurgião tenha que retirar a placa e desmontar todo o sistema para reposicioná-lo. Isso facilita a busca da DPA ideal, sem a necessidade de ...
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Histological remarks of the oviduct and the oviducal gland of Sympterygia acuta Garman, 1877
... glandular cells. Surface cells have the apical cytoplasm with plenty of droplets PAS and AB ...hand, cells located in the bottom of the folders have the supranu- clear cytoplasm occupied by vesicles ...
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Rev. Bras. Anestesiol. vol.64 número3
... En el grupo IR, se observó infiltración de células mono- nucleares en el área peritubular, especialmente en el área cortical, pérdida del borde en cepillo de las células del túbulo proximal, atrofia tubular, ...
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