Type III secretion
The Type III Secretion System-Related CPn0809 from Chlamydia pneumoniae.
... a type III secretion system (T3SS), which enables the pathogen to deliver, in a single step, effector proteins for modulation of host-cell functions into the human host cell cytosol to establish a ...
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Characterization of Salmonella type III secretion hyper-activity which results in biofilm-like cell aggregation.
... the type III secretion needle can be easily observed in a hyper-elongated form extending from the surface of strains that are altered in expression of key type III system components ...
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Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host.
... a type III secretion system (T3SS) that translocates bacterial effector proteins into host cells where their functions are essential for ...multi-cargo secretion chaperone that is functionally ...
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The Chlamydia trachomatis type III secretion substrates CT142, CT143, and CT144 are secreted into the lumen of the inclusion
... Type III secretion (T3S) systems are present in many Gram-negative bacteria establishing pathogenic or symbiotic relationships with their hosts. They mediate the delivery of bacteri- ally-encoded ...
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Structural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosa.
... Type III secretion systems (T3SS) are needle-like, membrane- anchored, multi-component complexes that enable a number of pathogenic bacteria to inject effectors from the cytosol directly into the ...
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A substrate-fusion protein is trapped inside the Type III Secretion System channel in Shigella flexneri.
... The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a single ...of ...
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The Serine Protease EspC from Enteropathogenic Escherichia coli Regulates Pore Formation and Cytotoxicity Mediated by the Type III Secretion System.
... a type III secretion system (T3SS) acting as a molecular syringe, EPEC injects numerous bacterial proteins into host cells that disrupt the intestinal epithelium ...
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Identification of novel protein-protein interactions of Yersinia pestis type III secretion system by yeast two hybrid system.
... Identification of protein interactions among various components of T3SS helps to predict and elucidate the structures and functions of the secretion machine. Many protein interactions in T3SS have been identified ...
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Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis.
... its type III secretion system to inject toxins into target cells, a crucial step in infection ...the secretion needle and take part in the translocation of anti-host effector proteins into the ...
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Weak Interactions between Salmonella enterica FlhB and Other Flagellar Export Apparatus Proteins Govern Type III Secretion Dynamics.
... The bacterial flagellum contains its own type III secretion apparatus that coordinates protein export with assembly at the distal end. While many interactions among export apparatus proteins have ...
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Regulation of the pore-forming translocon of the type III secretion system by the EspC Serine Protease in Enteopathogenic Escherichia Coli
... The secretion of EspC in the extracellular milieu is independent of ...EspC secretion is T3SS-independent, EspC is translocated into the epithelial cells in a process requiring active type III ...
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The Pseudomonas aeruginosa type III secretion system has an exotoxin S/T/Y independent pathogenic role during acute lung infection.
... The type III secretion system (T3SS) is a complex nanomachine of many pathogenic Gram-negative bacteria. It forms a proteinaceous channel that is inserted into the host eukaryotic cell membrane for ...
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Effect of the Salmonella pathogenicity island 2 type III secretion system on Salmonella survival in activated chicken macrophage-like HD11 cells.
... In order to better identify the role of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system (T3SS) in chickens, we used the well-known gentamicin protection assay with activated ...
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VE-cadherin cleavage by LasB protease from Pseudomonas aeruginosa facilitates type III secretion system toxicity in endothelial cells.
... LasB is known to proteolyse several extracellular proteins including elastin, fibronectin, vitronectin, surfactant proteins and serum complement components [10,11,32–36]. Extracellular ma- trix protein degradation by ...
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Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.
... Shigella MxiI associates with Naip2 to induce the interaction of Naip2 with Nlrc4, which presumably leads to Nlrc4 oligomeriza- tion and inflammasome activation. In the Salmonella system, cytosolic flagellin binds to ...
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Topology and organization of the Salmonella typhimurium type III secretion needle complex components.
... upon secretion [6], and a predicted single transmembrane domain (AA 207–227) close to its carboxy ...of type III dependent protein secretion (data not ...wild type and DinvG mutant ...
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Identification of type III secretion substrates of Chlamydia trachomatis using Yersinia enterocolitica as a heterologous system
... Figure 2 Identification of T3S signals in C. trachomatis proteins using Y. enterocolitica as a heterologous system. Y. enterocolitica T3S- proficient ( ΔHOPEMT) (A) and T3S-defective (ΔHOPEMT ΔYscU) (B) were used to ...
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Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems.
... Dot/Icm type IVB secretion system (T4BSS) is a pivotal determinant of Legionella pneumophila ...the type IVA secretion ...the type II and the type III secretion ...
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Research Article Type IV Secretion System Is Not Involved in Infection Process in Citrus
... The type IV secretion system (T4SS) is used by Gram-negative bacteria to translocate protein and DNA substrates across the cell envelope and into target ...the type III secretion system ...
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