[PDF] Top 20 Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells.
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Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells.
... deplete calpain 4, a small regulatory calpain subunit required for expression and activity of ubiquitously expressed calpains 1 and 2, in CD4+ T ...cells. ... See full document
9
4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.
... through 4-1BB receptor plays a multifaceted role in immune ...The 4- 1BB signaling significantly contributes to T cell activation, acquisition of effector function, and long-term ... See full document
13
The colocalization potential of HIV-specific CD8+ and CD4+ T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid.
... by T-cells (Figure S1), as previously described ...colonies in a Petri ...37uC in Yeast Peptone Dextrose (YPD) medium (BD ...cultured in YPD media 20% FBS and incubated for 4 ... See full document
18
Immune Dysfunction and the Pathogenesis of AIDS- associated non-Hodgkins Lymphoma
... hyperactivation is most marked when CD4 levels are low, we initiated studies to determine if CD8 T cells expressed immune stimulatory molecules normally expressed on CD4 helper T ... See full document
10
IM-1 – MURINE VISCERAL LEISHMANIASIS: CTLA-4 MEDIATED CD4+ T CELL SUPPRESSION IS EFFECTED THROUGH RELEASE OF TRANSFORMING GROWTH FACTOR-
... type in the inflammatory infiltrate of acute chagasic myocarditis induced by Berenice 78 (Be78) and Berenice 62 (Be62) Trypanosoma cruzi strains in dogs (Caliari et ...Like in other experimental ... See full document
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CD4+FoxP3+ regulatory T cells from Gαi2-/- mice are functionally active in vitro, but do not prevent colitis.
... embedded in OCT compound (Tissue- TekH, Miles Inc., Elkhart, IN), frozen in liquid nitrogen-cooled isopentane and stored at ...fixed in 100% cold acetone for 10 min prior to H&E or ... See full document
10
Fyn kinase is required for optimal humoral responses.
... immunization is a complex process principally involving DCs, T and B ...kinase in T cell-mediated antibody production [1,28–30] we sought to determine the contribution of this kinase ... See full document
8
Chemokine (C-C motif) ligand 20, a potential biomarker for Graves' disease, is regulated by osteopontin.
... for 1–3 months until reaching normal TSH, FT3, and FT4 values as the euthyroid state but TRAb level was just slightly decreased compared to initial GD ...for 1–2 years until TSH, FT3, FT4 as well as TRAb ... See full document
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Rev. Bras. Reumatol. vol.56 número1
... tri-functional cells relative to all cells produc- ing any one of the analyzed cytokines, we did find a significant difference in cultures stimulated with PMA/Io, where samples from patients with ... See full document
9
High efficiency of antiviral CD4(+) killer T cells.
... processed in parallel and incubated with unrelated peptides or were left ...of 1:1 in PBS; in some cases, a third target population was included and labeled with 25 nM ...indicated ... See full document
12
Microbial Translocation and B Cell Dysfunction in Human Immunodeficiency Virus Disease
... activation in HIV infection: HIV infection induces broad immune perturbation, including dysfunction and loss of CD4+ T cells and B cells (Grossman et ...infects CD4+ T ... See full document
8
NY-ESO-1-specific circulating CD4+ T cells in ovarian cancer patients are prevalently T(H)1 type cells undetectable in the CD25+ FOXP3+ Treg compartment.
... ESO-specific T cells were isolated from peptide-stimulated cultures by IFN-c secretion assay- (Miltenyi Biotec) or tetramer- guided flow cytometry cell sorting and expanded by stimulation with PHA and ... See full document
9
BAFF promotes regulatory T-cell apoptosis and blocks cytokine production by activating B cells in primary biliary cirrhosis
... (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune ...unclear. CD4+ +CD25+ + regulatory T cells (Tregs) play a critical role in self-tolerance and, for ... See full document
7
CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo.
... T cells was determined (Figure ...observed in both naı¨ve and infected mice, demonstrating that this phenomenon is not dependent on ...Treg cells (by intracellular cytokine ... See full document
14
Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.
... CD4 T cell populations were sorted from uninfected PBMC (n = 5), HIV-infected PBMC (n = 5) and uninfected human tonsils (n = 4) based on expression of CCR7, CXCR5, CD150, CCR6 and PD-1 for ... See full document
14
Activation of blood T-cells in HIV/HCV co-infected patients
... ART in the form of HIV VL reduction to an undetectable level does not guarantee restoration of IS ...It is pro- ved by increase of non-AIDS-related cancers frequ- ency, such as non-Hodgkin ... See full document
8
HIV and mature dendritic cells: Trojan exosomes riding the Trojan horse?
... observed in co- cultures where mDCs were previously pulsed either with HIV Gag-eGFP VLPs (Top) or Jurkat-derived exosomes labeled with DiI (Bottom), extensively washed, and then allowed to interact with Jurkat ... See full document
9
Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.
... identified in our study might also harbor interesting ...of T cell signaling proteins SH2D2A, HSH2D, and ...signaling is further increased by parallel targeting of one protein by several ...Pyk2 ... See full document
11
An overview of the effects of annexin 1 on cells involved in the inflammatory process
... ANXA1 is modulated by GC treat- ment, several studies have examined the role of exogenous ANXA1 and its derived peptides on various aspects of monocyte and macrophage inflammatory ...monocytes in ... See full document
10
Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis
... Igure 1: Initial stages of the sensiti- zation in contact dermatites. 1) The nickel (Ni2+), cobalt (Co2+) and pal- ladium (Pd) ions, or fragments of hy- aluronic acid (HA) generated by some contact ... See full document
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