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[PDF] Top 20 Actin cytoskeleton-dependent and -independent host cell invasion by Trypanosoma cruzi is mediated by distinct parasite surface molecules

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Actin cytoskeleton-dependent and -independent host cell invasion by Trypanosoma cruzi is mediated by distinct parasite surface molecules

Actin cytoskeleton-dependent and -independent host cell invasion by Trypanosoma cruzi is mediated by distinct parasite surface molecules

... of host cell actin cytoskeleton as a facilitator of Trypanosoma cruzi invasion has been reported by some authors, while other workers claim that it instead inhibits ... See full document

7

Fibronectin-Degrading Activity of Trypanosoma cruzi Cysteine Proteinase Plays a Role in Host Cell Invasion

Fibronectin-Degrading Activity of Trypanosoma cruzi Cysteine Proteinase Plays a Role in Host Cell Invasion

... forms is associated with cruzipain activity. To certify that FN from cell culture medium binds to the MT surface, the parasites were incubated for 1 h in DMEM-FBS and subsequently processed ... See full document

9

Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms

Mammalian cell invasion and intracellular trafficking by Trypanosoma cruzi infective forms

... entering host cells, trypomastigotes are usually found in an acidic membrane-bound com- partment referred to as phagosome or parasito- phorous vacuole (PV), from where they eventually escape to differentiate into ... See full document

18

Molecular basis of mammalian cell invasion by Trypanosoma cruzi

Molecular basis of mammalian cell invasion by Trypanosoma cruzi

... Burleigh and Andrews 1998, Yoshida 2003). Attachment of try- pomastigotes is receptor-mediated and is restricted to cell surface domains (Schenkman et ...to and ... See full document

25

Use of L-Proline and ATP Production by Trypanosoma cruzi Metacyclic Forms as Requirements for Host Cell Invasion

Use of L-Proline and ATP Production by Trypanosoma cruzi Metacyclic Forms as Requirements for Host Cell Invasion

... the parasite infectivity, were ...content and the ability of starved parasites to enter HeLa cells; glucose treatment exhibited some effect, whereas L -glutamic acid treatment had no effect ...levels ... See full document

10

Membrane cholesterol regulates lysosome-plasma membrane fusion events and modulates Trypanosoma cruzi invasion of host cells.

Membrane cholesterol regulates lysosome-plasma membrane fusion events and modulates Trypanosoma cruzi invasion of host cells.

... molecules and consequently stimulate cells by distinct mechanisms ...TCT host cell entry was indeed due to cholesterol removal from host cell plasma membrane, since ... See full document

13

Molecular Characterization of Trypanosoma cruzi SAP Proteins with Host-Cell Lysosome Exocytosis-Inducing Activity Required for Parasite Invasion

Molecular Characterization of Trypanosoma cruzi SAP Proteins with Host-Cell Lysosome Exocytosis-Inducing Activity Required for Parasite Invasion

... T. cruzi is continuously releasing vesicles enriched in surface antigens involved in host-cell invasion, such as glycoproteins of the GP85/TS ...secreted by T. ... See full document

11

Features of host cell invasion by different infective forms of Trypanosoma cruzi

Features of host cell invasion by different infective forms of Trypanosoma cruzi

... observed by phalloidin staining. By contrast, trypomastigotes preferentially enter HeLa cells at the edges showing that the different forms of the parasite interact with specific regions of the ... See full document

3

Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion

Trypanosoma cruzi subverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion

... T. cruzi trypomastigotes attach and invade host cells by their posterior end, where the base of the lagellum is ...provided by the host cell, because the ... See full document

13

A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells?

A century of research: what have we learned about the interaction of Trypanosoma cruzi with host cells?

... T. cruzi components involved in invasion are molecules belong- ing to the Gp85/trans-sialidase superfamily (Gp85/TS) and mucin-like proteins present on the surface of the ...encoded ... See full document

13

(São Paulo, online)  vol.4 número5

(São Paulo, online) vol.4 número5

... signals, and also phosphorylate STMN1of unknown function, that is frequently up-regulated in transformed ...various cell-surface receptors results in extensive phosphorylation of Op18 ... See full document

10

HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.

HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells.

... FA and the cytoskeleton in SMMC-7721 and K7721 ...(E) Cell lysates from K7721 cells expressing WT-CD147 and glycosylation site-mutated CD147 were analyzed by Western blotting ... See full document

8

Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation.

Untangling the Diverse and Redundant Mechanisms of Staphylococcus aureus Biofilm Formation.

... aureus is highly unlikely to have retained the capacity to express multiple biofilm phenotypes when just one would suffice, it seems reasonable to suggest that these environmen- tally regulated biofilm mechanisms ... See full document

6

NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production

NLRP3 Controls Trypanosoma cruzi Infection through a Caspase-1-Dependent IL-1R-Independent NO Production

... maturation and secretion of the pro-inflammatory cyto- kines IL-1b and IL-18 and the induction of pyroptosis, a specialized form of inflammatory cell death, are the major effector mechanisms ... See full document

11

Myenteric plexus is differentially affected by infection with distinct Trypanosoma cruzi strains in Beagle dogs

Myenteric plexus is differentially affected by infection with distinct Trypanosoma cruzi strains in Beagle dogs

... slow and progressive parasite multiplica- tion (Andrade ...T. cruzi kDNA and cy- tokines are more frequently associated with parasitism maintenance in the oesophagus as opposed to the colon ... See full document

10

The importance of pathogen load.

The importance of pathogen load.

... load is assessment of parasitemia—the percentage of infected red blood cells ...anemia is a common consequence of malaria, and so the pathogen burden in blood is more accurately quantified ... See full document

2

Internalization of Components of the Host Cell Plasma Membrane During Infection by Trypanosoma cruzi

Internalization of Components of the Host Cell Plasma Membrane During Infection by Trypanosoma cruzi

... played by sia- loglycoconjugates due to the influence of sialic acid residues on the interaction process (Meirelles et ...residues by neuraminidase treatment (Araújo-Jorge & de Souza 1984), blockage of ... See full document

5

Ordered patterns of cell shape and orientational correlation during spontaneous cell migration.

Ordered patterns of cell shape and orientational correlation during spontaneous cell migration.

... of cell shape during spontaneous cell migration. WT STA cell 1 maintained a larger Amp(h,t) at both 80u and 260u angles, meaning that the cell stably maintained its elongated morphology ... See full document

14

REPOSITORIO INSTITUCIONAL DA UFOP: Genetic modulation in Be-78 and Y Trypanosoma cruzi strains after long-term infection in Beagle dogs revealed by molecular markers.

REPOSITORIO INSTITUCIONAL DA UFOP: Genetic modulation in Be-78 and Y Trypanosoma cruzi strains after long-term infection in Beagle dogs revealed by molecular markers.

... band, and in the MDH enzyme, compatible with ZB (TcVI of Zingales et ...(TcII) and ZB (TcVI) zimodemes in isolates of Be-78 strain obtained from dogs experimentally infected for 7–12 ...shown by the ... See full document

8

Molecular identification of a malaria merozoite surface sheddase.

Molecular identification of a malaria merozoite surface sheddase.

... complex is an abundant merozoite component, and together with AMA1 likely corresponds to the surface structures shed adjacent to the moving ...AMA1 and the MSP1 complex can occur even in the ... See full document

11

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