[PDF] Top 20 DNA Methylation Landscapes of Human Fetal Development.
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DNA Methylation Landscapes of Human Fetal Development.
... biopsies of human adult tissues [3,15], the methylation profiles we report reflect the average of multiple cell ...complexity of the organs investigated led to an underestimation ... See full document
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Integrative genome-wide gene expression profiling of clear cell renal cell carcinoma in Czech Republic and in the United States.
... the DNA methylation patterns in ccRCC versus corresponding non-tumour renal tissue using the following thresholds: FC $2 and BH FDR-adjusted p-value ...total of 916 and 16,469 CpG sites were ... See full document
15
Dynamics of DNA Methylation during Early Development of the Preimplantation Bovine Embryo
... 0% methylation control, bovine embryonic fibroblast cells derived from skin cells of a fetus at 2–3 mo of gestation were cultured for 1 wk in a culture medium composed of 89% (v/v) Dulbecco’s ... See full document
10
Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.
... The methylation of PCGTs, which is triggered by age and by environmental factors that are associated with cancer development, reduces cellular differentiation and leads to the accumulation of ... See full document
15
Androgen receptor function links human sexual dimorphism to DNA methylation.
... determinants of development, health and ...inactivation of the androgen receptor, the key regulator of normal male sex development, is associated with differences of the patterns ... See full document
8
Avaliação do padrão de metilação de regiões promotoras dos genes ESR1, ESR2 e PGR na endometriose profunda intestinal
... the development of complex human disorders, including cancer and neurodegenerative, neurological and autoimmune diseases ...basis of epigenetic effects because they can alter gene expression ... See full document
86
Genome-wide DNA methylation patterns and transcription analysis in sheep muscle.
... DNA methylation plays a central role in regulating many aspects of growth and development in mammals through regulating gene ...The development of next generation sequencing ... See full document
7
Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.
... GeneChipH Human Gene ...ng of total RNA with the AmbionH WT Expression kit (Ambion, Austin, TX, USA) and the AffymetrixH GeneChip WT Terminal Labeling kit ...composed of the Scanner 3000 7G ... See full document
13
The prima donna of epigenetics: the regulation of gene expression by DNA methylation
... neuron development and synapse formation. Neuronal exclusive expression of neuron-specific genes is controlled by epigenetic mechanism mainly associated with histone ...region of neuron-specific ... See full document
11
A novel method for identification and quantification of consistently differentially methylated regions.
... DMRs of astrocytomas located in the promoter region of genes are highly related to DNA binding factors and transcription; this is particularly true for homeobox ...aberrant methylation may ... See full document
11
Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues.
... limitation of our study is the small numbers of samples evaluated; however, these provide the first evidence for the stability of DNA methylation during prenatal and early postnatal ... See full document
13
Age-related Changes in DNA Methylation Status of hTERT Gene Promoter of Oral Epithelial Cells
... range of characteristics (hypomethylation and hypermethylation), typically associated with the aging process could be explained by some ...that DNA methyltransferase (DNMT) activity decreased with the ... See full document
8
Performance of Different Analytical Software Packages in Quantification of DNA Methylation by Pyrosequencing.
... cells DNA methylation mainly involves a Cytosine when it is followed by a Guanine (CpG dinucleotides or CpG sites) ...Most of the mammalian genes contain CpGs clustered in short regions called CpG ... See full document
12
DNA methylation dynamics in human induced pluripotent stem cells over time.
... DNA methylation is an important epigenetic modification and is a key component in normal differentiation, development and disease ...Expression of tissue-specific genes, such as Oct-4 [4], ... See full document
14
Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes.
... progression. Methylation-sensi- tive quantitative real-time PCR (qPCR) of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in ...amylin DNA (cfDNA) may serve as ... See full document
15
Function and evolution of DNA methylation in Nasonia vitripennis.
... extractions of female early embryo (0–10 h), late embryo (18–30 h), 1st instar larvae, and ...groups of 20 females for 24 h to induce production of ...surface of the host and transfer them ... See full document
20
Estimation of the fraction of cancer cells in a tumor DNA sample using DNA methylation.
... Contamination of normal cells is almost always present in tumor samples and affects their molecular ...analyses. DNA methylation, a stable epigenetic modification, is cell type-dependent, and ... See full document
10
Estabilidade do controle epigenético em células humanas normais e transformadas
... O modelo de células normais apresentou modificações epigenéticas no controle de expressão dos genes “imprintados” IGF2 e H19 quando comparado à linhagem celular primária. Ainda assim, manteve a expressão de genes ... See full document
34
Morphological changes of Paulownia seedlings infected phytoplasmas reveal the genes associated with witches' broom through AFLP and MSAP.
... sion. DNA methylation is one of the mechanisms in regulating gene expressions [30], similar results were also reported in Tomato Yellow Leaf Curl Sardinia Virus-Tomato [14] and Mycosphaerella ... See full document
9
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression.
... next of kin is not required, because relatives have no possibility for ...probes of the present study originate from these ...Committee of the LMU Munich approved this ...cause of death was ... See full document
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