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[PDF] Top 20 Evaluation of cytotoxic and genotoxic effects of Microcystin-LR in Saccharomyces cerevisiae

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Evaluation of cytotoxic and genotoxic effects of Microcystin-LR in Saccharomyces cerevisiae

Evaluation of cytotoxic and genotoxic effects of Microcystin-LR in Saccharomyces cerevisiae

... direction of DNA ...used in the single gel assay, the usual 1.5% and a ...0.7% and 1.3%, respectively, since the gel mix is made with 50% of cells suspension and 50% of ... See full document

87

Evaluation of cytotoxic and genotoxic effects of Microcystin-LR in Saccharomyces cerevisiae

Evaluation of cytotoxic and genotoxic effects of Microcystin-LR in Saccharomyces cerevisiae

... involved in the validation of some of the project techniques: Doutora Maria João Silva and Doutora Henriqueta Louro of the Human Genetics Department at Instituto Nacional de Saúde ... See full document

8

Assessment of Duguetia furfuracea genotoxic and cytotoxic activity in bacteria and mice

Assessment of Duguetia furfuracea genotoxic and cytotoxic activity in bacteria and mice

... that cytotoxic agents can induce a great variety of events in the cell: DNA or protein damage, inhibition of growth, apoptosis, ...nature of the interaction between a drug and ... See full document

8

Evaluation of genotoxic and cytotoxic effects of hydroalcoholic extract of Euphorbia tirucalli (Euphorbiaceae) in cell cultures of human leukocytes

Evaluation of genotoxic and cytotoxic effects of hydroalcoholic extract of Euphorbia tirucalli (Euphorbiaceae) in cell cultures of human leukocytes

... concentration in the crude extract was measured spectrophotometrically using a modifi ed Folin-Ciocalteau method (Chandra and Gonzalez de Mejia ...mL of 2 N Folin-Ciocalteau reagent to 1 mL of ... See full document

12

Evaluation of stress tolerance and fermentative behavior of indigenous Saccharomyces cerevisiae

Evaluation of stress tolerance and fermentative behavior of indigenous Saccharomyces cerevisiae

... growth of S. cerevisiae strains were not affected by the ...decline in the yeast presence (Figure 4c). In the lit- erature, we can find some reports of yeast and bacterial ... See full document

10

Cytotoxic and genotoxic evaluation of cotinine using human neuroblastoma cells (SH-SY5Y)

Cytotoxic and genotoxic evaluation of cotinine using human neuroblastoma cells (SH-SY5Y)

... metabolite of nicotine, which is metabolized in the liver through a cytochrome P450 ...single and double DNA strand breaks and micronuclei formation, but little is known about the effect ... See full document

7

Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro

Human mesenchymal stem cells are resistant to cytotoxic and genotoxic effects of cisplatin in vitro

... assay evaluation of CIS cytotoxicity, cells were seeded in 96-well plates at a density of 3 x 10 3 cells/well for MSCs and 5 x 10 4 cells/well for OVCAR-3 cells and treated the ... See full document

6

In vivo evaluation of the antimutagenic and antigenotoxic effects of b-glucan extracted from Saccharomyces cerevisiae in acute treatment with multiple doses

In vivo evaluation of the antimutagenic and antigenotoxic effects of b-glucan extracted from Saccharomyces cerevisiae in acute treatment with multiple doses

... modifications and under indi- rect light. Briefly, 20 mL of a blood cell suspension was em- bedded into 120 mL of ...agarose and layered onto a pre-coated slide with a thin layer of ... See full document

12

Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L. (Asteraceae) in vitro and in Saccharomyces cerevisiae

Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L. (Asteraceae) in vitro and in Saccharomyces cerevisiae

... oxidizing effects of hydrogen peroxide. The strain of S. cerevisiae wild (Sodwt) showed a higher level of survival in the pre-treatment and co- treatment, while the ... See full document

12

Assessment of genotoxic, cytotoxic, and protective effects of Salacia crassifolia (Mart. Ex. Schult.) G. Don. stem bark fractions in mice

Assessment of genotoxic, cytotoxic, and protective effects of Salacia crassifolia (Mart. Ex. Schult.) G. Don. stem bark fractions in mice

... described in von Ledebur and Schmid (1973). For each treatment, groups of 5 animals were treated orally with 50, 100, or 150 mg/kg HEF, EAF, or HAF, according to body weight, for the ... See full document

11

A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cells.

A genomic screen revealing the importance of vesicular trafficking pathways in genome maintenance and protection against genotoxic stress in diploid Saccharomyces cerevisiae cells.

... S. cerevisiae is one of the best-explored models of eukaryotic cells in relation to genome maintenance mechanisms, considerable information on this topic remains to be de- termined, including ... See full document

32

Saccharomyces cerevisiae and in vivo evaluation of their immunomodulatory effects

Saccharomyces cerevisiae and in vivo evaluation of their immunomodulatory effects

... peroxidation in naïve control rats, whereas the low MW BG (70,000 g/mol) did the same in the enteritis groups, which suggest that low MW BG supplementation enhanced the antioxidant capacity of the ... See full document

9

Evaluation of in vivo and in vitro toxicological and genotoxic potential of aluminum chloride

Evaluation of in vivo and in vitro toxicological and genotoxic potential of aluminum chloride

... Aluminum and its compounds are common contaminants of water and food, as well as medications and ...distribution of the element facilitates the demand for detailed studies of its ... See full document

8

Synthesis and evaluation of cytotoxic effects of Aminoester derivatives of natural α , β Amyrin mixture

Synthesis and evaluation of cytotoxic effects of Aminoester derivatives of natural α , β Amyrin mixture

... series of novel aminoacetyl α,β-amyrin derivatives were synthesized and their cytotoxic activities were evaluated against human colon carcinoma HCT-116, human acute promyelocytic leukemia HL-60 ... See full document

8

Cytotoxic and genotoxic effects of cadmium in human osteoblasts

Cytotoxic and genotoxic effects of cadmium in human osteoblasts

... injected in the flow chamber where each cell is run through a light beam, perpendicular to the ...focusing of sample flow injected through a saline solution (sheath fluid) which also runs through the flow ... See full document

52

Mechanisms and control of mRNA turnover in the yeast saccharomyces cerevisiae.

Mechanisms and control of mRNA turnover in the yeast saccharomyces cerevisiae.

... pool of mRNAs into a nontranslating state, new mRNAs that are required for the cellular stress response might be preferentially translated because of reduced competition from the pre-existing ...assist ... See full document

190

Protective effects of steroidal alkaloids isolated from Solanum paniculatum L. against mitomycin cytotoxic and genotoxic actions

Protective effects of steroidal alkaloids isolated from Solanum paniculatum L. against mitomycin cytotoxic and genotoxic actions

... Human and Animal Research Ethics Committee of the Universidade Federal de Goiás (CEPMHA/HC/UFG number ...House of the Universidade Federal de Goiás, were randomly allocated to treatment ... See full document

8

Regulation of mitochondrial function by Isc1p and Sch9p in Saccharomyces cerevisiae

Regulation of mitochondrial function by Isc1p and Sch9p in Saccharomyces cerevisiae

... involved in the regulation of cell growth and survival, namely the TOR (Target of Rapamycin) ...Virgilio and Loewith, 2006; Dann and Thomas, 2006; Laplante and Sabatini, ... See full document

93

Genetic studies of mitochondrial DNA in Saccharomyces cerevisiae

Genetic studies of mitochondrial DNA in Saccharomyces cerevisiae

... establishment of an equivalent mtDNA sequence, we obtained basic statistics for the total set of ...percentage of T and A is very high (72.28% of the total nucleotides) comparable with ... See full document

61

Calcium dependence of eugenol tolerance and toxicity in Saccharomyces cerevisiae.

Calcium dependence of eugenol tolerance and toxicity in Saccharomyces cerevisiae.

... monitored in cells following exposure to eugenol (in identical conditions to that used to assess cell viability shown in Figures 1B and C) using the genetically encoded reporter, aequorin, ... See full document

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