[PDF] Top 20 Evolution of the thyroid hormone-binding protein, transthyretin
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Evolution of the thyroid hormone-binding protein, transthyretin
... group of proteins, which includes thyroxine-binding globulin and albumin, that bind to and transport thyroid hormones in the ...in the carriage of vita- min A through the ... See full document
15
Hormone affinity and fibril formation of piscine transthyretin: the role of the N-terminal
... form of TTR is a tetramer and this structure is required to bind ...TTR-TH binding studies HPLC/gel chromatography was performed in order to determine if the molecular mass of sbTTRWT and ... See full document
45
High resolution crystal structures of piscine transthyretin reveal different binding modes for triiodothyronine and thyroxine
... species. The areas of the cavity enclosing the inner phenolic and the outer tyrosyl rings of the hormone are clearly narrower in fish ...comparing the ... See full document
7
A component of retinal light adaptation mediated by the thyroid hormone cascade.
... by binding to the T3 response element (TRE) composed of repeated DNA sequences with different ...configurations. The consensus sequence recognized by nuclear receptors often contains a hexamer ... See full document
9
Dissecting the Relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter.
... disrupts the TR dimer binding and increases the intensity of monomer binding to a TRE in a dose-dependent ...disruption of the TR dimer binding by T3 was believed ... See full document
10
Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids.
... by the TR has been shown for Hr and Klf9 in established neural cell lines ...targets of T3, given that the effect of the hormone was not blocked by previous treatment with CHX to ... See full document
8
Identification of thyroid hormone receptor binding sites and target genes using ChIP-on-chip in developing mouse cerebellum.
... ml) of the sonicated solution was store at 220uC as TI, while the remainder was incubated with anti-TRb polyclonal antibody (PA1-213, cloneTRb-62, Affinity Bioreagents, Golden, CO) overnight with ... See full document
12
Nematode and Arthropod Genomes Provide New Insights into the Evolution of Class 2 B1 GPCRs
... G protein-coupled receptor (GPCR) gene families have been identified and are characterized by the presence of seven helical transmembrane (TM) structures ...[1,2]. The Secretin-like family ... See full document
17
Transthyretin and thyroid hormone transport in fish and the effect of endocrine disruptors on this process
... characterised protein in higher vertebrates. It is a plasma protein involved in the transport of thyroid hormones and vitamin ...is the object of intensive research. ... See full document
203
A Novel Mutation of Thyroid Hormone Receptor Beta (I431V) Impairs Corepressor Release, and Induces Thyroid Hormone Resistance Syndrome
... brief, the plasmi- ds were transformed into BL21, cultured into 2xLB medium, pelleted and resuspended in 1xTST buffer (50mM Tris pH ...Then, the solution was incubated with lysozyme and sonicated (three ... See full document
9
Hyponatremia after Thyroid Hormone Withdrawal in a Patient with Papillary Thyroid Carcinoma
... diagnose the underlying etiol- ogy of the hyponatremia and correct it appropriately because severe hyponatremia can cause serious complications and substan- tially increase the risk of ... See full document
6
Rev. Assoc. Med. Bras. vol.46 número2
... inhibitor of bone reab- sorption and its partial or total deficiency may represent the loss of an important bone-protecting factor among patients, with bone tissue becoming more vulnerable to ... See full document
5
The Influence of Small Amounts of Aluminium on the Spheroidization of Cast Iron with Cerium Mischmetal
... influence of aluminium (added in quantity from about ...both the alloy matrix and the shape of graphite precipitates in cast iron treated with a fixed amounts of cerium mischmetal ...in ... See full document
6
Selection of the temperature of casting the bronzes to plaster moulds
... to the temperature suita- bly: 1200 °C, 1180 °C, 1160 °C and 1140 °C, and then the mould was casted - probe TDAg and plaster mould with thin-walled, so- called casts test slats about dimensions: the ... See full document
6
J. Bras. Patol. Med. Lab. vol.52 número5
... for the PI3K domain were identiied by searching the PDB database with HHpred using default ...from the template structure of human phosphatidylinositol 3-kinase catalytic subunit type 3, which ... See full document
14
Arq Bras Endocrinol Metab vol.56 número1
... manifestations of RTH are extreme- ly variable, the majority of patients being completely ...inding of elevated serum T4 levels, usually accompanied by high serum levels of T3, as- ... See full document
5
THYROID HORMONE PROFILE IN EARLY BREAST CANCER PATIENTS
... that thyroid hormone modulates mammotrophic effect of prolactin and hypothyroidism permits increased prolactin activity which may lead to mammary dysplasia and neoplastic ...[7] The possible ... See full document
3
Relationship between heart rate variability and subclinical thyroid disorders of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
... subclinical thyroid dysfunctions and autonomic modulation changes has been described by many studies with conflicting ...analyze the association between subclinical hyperthyroidism (SCHyper), subclinical ... See full document
8
Oral triiodothyronine for the prevention of thyroid hormone reduction in adult valvular cardiac surgery
... performed the surgical procedures according to a rou- tine practice guideline for surgery and anes- ...cannulation. The filling volume in the cardiopulmonary bypass cir- cuit was 1700 mL and ... See full document
10
A Method To Find The Area Of Sector Without The Usage Of Angle Made By The Chord
... then the theorem is ...Thus the equation of circle is x²+y²=r².The equation of the chord at ‘a’ distance from center is ax-ry- ar=0 or Y= ... See full document
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