[PDF] Top 20 GLUCAGON-LIKE PEPTIDE 1: BIOChEMISTRy, SECRETION AND MAIN PhySIOLOGICAL EFFECTS
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GLUCAGON-LIKE PEPTIDE 1: BIOChEMISTRy, SECRETION AND MAIN PhySIOLOGICAL EFFECTS
... insulin secretion and inhibit glucagon secretion, combined with its chronic action to maintain beta-cell mass, suggest glp-1 as a useful agent in the treatment of type 2 diabetes ... See full document
10
THE GLP-1 SYSTEM: BIOCHEMISTRY, PHYSIOLOGICAL EFFECTS AND THE ROLE OF DDP-IV INHIBITORS IN THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS
... O Glucagon-like peptide-1 (GLP-1) é uma hormona peptídica que controla a glicemia, preserva e previne a perda das células-β mas é rapidamente degradada pela dipeptidyl peptidase-IV ... See full document
11
Clinical Application of Glucagon-Like Peptide 1 Receptor Agonists for the Treatment of Type 2 Diabetes Mellitus
... Glucagon-like peptide 1 (GLP-1) is secreted from enteroendocrine L-cells in response to oral nutrient intake and elicits glucose- stimulated insulin secretion while ... See full document
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STUDY OF PALM OIL AND GLUTAMINE AS FUNCTIONAL FOODS ON PEPTIDE TYROSINE TYROSINE (PYY) AND GLUCAGON-LIKE PEPTIDE 1 (GLP-1) IN OBESE PATIENTS FOLLOWING UP ON THE AMBULATORY HEALTH SERVICES OF THE PUBLIC HOSPITAL
... overweight and obese people has increased worldwide over several decades and is a difficult problem to ...the secretion of intestinal peptides have been used for the control of type 2 diabetes ... See full document
13
Einstein (São Paulo) vol.12 número2
... complex and involves, besides the secretion and action of insulin and glucagon, a hormonal and neural mechanism, regulating the rate of gastric ...extrinsic and intrinsic ... See full document
3
Glucagon-like peptide-1 secretory function as an independent determinant of blood pressure: analysis in the Tanno-Sobetsu study.
... Glucagon-like peptide 1 (GLP-1), one of the incretins, is secreted from L-cells in the small intestine after meals, contrib- uting to enhancement of post-prandial insulin ... See full document
8
Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice.
... glucose and lipid homeostasis. Efforts to utilize GLP-1 analogs or GLP-1R agonists in the treatment of T2DM and obesity have lasted for ...Exendin-4 and Liraglutide [19] - injectable peptidic ... See full document
15
The glucagon-like peptide 1 analogue Exendin-4 attenuates the nicotine-induced locomotor stimulation, accumbal dopamine release, conditioned place preference as well as the expression of locomotor sensitization in mice.
... gastrointestinal peptide glucagon-like peptide 1 (GLP-1) is known to regulate consummatory behavior and is released in response to nutrient ...this peptide recently ... See full document
7
Albiglutide, a long lasting glucagon-like peptide-1 analog, protects the rat heart against ischemia/reperfusion injury: evidence for improving cardiac metabolic efficiency.
... disposal and glycolytic production of lactate by peripheral insulin sensitive tissue as plasma glucose was significantly reduced with ...efflux and increased lactate ...deleterious effects, but ... See full document
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Beneficial Effects of Evogliptin, a Novel Dipeptidyl Peptidase 4 Inhibitor, on Adiposity with Increased Ppargc1a in White Adipose Tissue in Obese Mice.
... resistance and type 2 diabetes because adipose tissue, which secretes various adipokines with autocrine and paracrine action, is central to the control of energy storage and whole body insulin ... See full document
19
Mathematical Modeling of Interacting Glucose-Sensing Mechanisms and Electrical Activity Underlying Glucagon-Like Peptide 1 Secretion.
... conditions, and with default parameters, completely abolished electrical activity and reduced Ca 2+ influx (Fig ...[24] and considering heterogeneity between cells, we further analyzed the model ... See full document
26
Pancreatic α-Cell Dysfunction in Type 2 Diabetes: Old Kids on the Block
... inappropriate glucagon level also largely exacerbate fasting hyperglycemia in ...fasting glucagon levels that can be 50% greater than nondiabetic subjects ...composition and failure of adjacent ... See full document
9
Development of lipid nanocapsules encapsulating exenatide for oral delivery in the treatment of type 2 diabetes mellitus
... péptido 1 semelhante ao glucagon, é essencial para evitar a administração de injeções diárias dolorosas, permitindo desta forma uma maior adesão à terapêutica por parte dos ...péptido 1 semelhante ao ... See full document
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Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion.
... insulin secretion in response to high glucose challenge, synapto- tagmin-7 KO mice exhibit normal resting insulin levels under non- stressed conditions when the mice have free access to feed ([4] and data ... See full document
7
Effects of subcutaneous carbon dioxide on calcitonin gene related peptide and substance P secretion in rat skin
... reticulum and processed in the Golgi ...kDa, and released in the interstitium upon a local ...rats and quantiied pro-CGRP to prove the release and increase in CGRP production during the ... See full document
7
Protease-activated receptor 2 mediates mucus secretion in the airway submucosal gland.
... mucus secretion from airway submucosal glands is essential to maintain the airway defense ...mucus secretion may result in failure of host defense against pathogens, which in turn could be the underlying ... See full document
8
Letter: Expression of Glucagon-Like Peptide-1 Receptor in Papillary Thyroid Carcinoma and Its Clinicopathologic Significance ( 2014;29:536-44, Min Jung Jung et al.)
... GLP-1R expression in PTC was an unexpected finding, and no studies have reported the clinical significance of GLP-1R expression in PTC or the pathogenic mechanism until now. For- tunately, 18 of 56 cases in this ... See full document
2
The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis.
... 2008, and of these 500 million were obese ...production and/or ...obesity and increased risk of major complications in type 2 diabetes, including mortality is well documented [3] and ... See full document
14
Preservation of the blood brain barrier and cortical neuronal tissue by liraglutide, a long acting glucagon-like-1 analogue, after experimental traumatic brain injury.
... moderate and severe traumatic brain injury (TBI), and a significant risk factor for development of neuronal death and deterioration of neurological ...edema and neuronal death after TBI are ... See full document
17
Evolution of the glucagon-like system across fish
... (Lund et al., 1982; Lund et al., 1983; Andrews et al., 1986; Nichols et al., 1988) Coho salmon (Oncorhynchus kisutch) Pancreas (29) Pancreas (31) (Plisetskaya et al., 1986) Channel catfish (Ictalurus punctata) Pancreas ... See full document
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