[PDF] Top 20 Glycomic Approaches for the Discovery of Targets in Gastrointestinal Cancer
Has 10000 "Glycomic Approaches for the Discovery of Targets in Gastrointestinal Cancer" found on our website. Below are the top 20 most common "Glycomic Approaches for the Discovery of Targets in Gastrointestinal Cancer".
Glycomic Approaches for the Discovery of Targets in Gastrointestinal Cancer
... reveals the colocaliza- tion between specific proteins and specific glycan structures in tissues and cell ...samples. The identification of protein glycoforms is of utmost importance ... See full document
19
From Medicinal Chemistry to Human Health: Current Approaches to Drug Discovery for Cancer and Neglected Tropical Diseases
... one of these studies, potent ...structure of the enzyme previously obtained in our research group was used in molecular docking efforts by which a series of deazaguanine ... See full document
17
Bioinformatics strategies for identification of cancer biomarkers and targets in pathogens associated with cancer
... treatment in the disease state. A number of assays have been developed to identify ...role in medicinal biology. 4–7 In medicine, a biomarker generally refers to a specific protein ... See full document
239
Comprehensive serum profiling for the discovery of epithelial ovarian cancer biomarkers.
... Many approaches have been taken to improve the performance of ...reported in a retrospective study using serial CA-125 measurements interpreted by a Risk of Ovarian Cancer ... See full document
10
Assessment of Notch1 Ligands production - Key Protein Targets in Breast Cancer
... decreasing the temperature; 2) Using a highly soluble fusion partner that drives the overall solubility of the fusion protein, such as Maltose-binding Protein (MBP), Small Ubiquitin Modifier ... See full document
107
Early detection and personalized treatment in oral cancer: the impact of omics approaches
... Gain in the 3q26 region, which contains the hTERC and SOX2 genes, is common in all squamous cell carcinomas and their de- tection could be important for early detection and for accurate ... See full document
7
Machine learning approaches for predicting effects of drug combinations in cancer
... drug targets, pathway information, and chemical ...from the remaining datasets could solely be used in an indirect manner, to infer prior knowledge to aid feature ...restricting the input ... See full document
88
Biomarker Discovery in Human Prostate Cancer: an Update in Metabolomics Studies
... Prostate cancer (PCa) is the most frequently diagnosed cancer and the second leading cause of cancer death among men in Western ...on the measurement of ... See full document
14
Glycoengineered cell models for the characterization of cancer O-glycoproteome: an innovative strategy for biomarker discovery
... allowed the generation of unlimited amounts of material for straightforward isolation and identifica- tion of GalNAc-O-glycopeptides from total cell lysates, or even from secretions using ... See full document
11
Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods.
... used in drug discovery research in recent years and it has become an important step in the drug discovery ...process. The screening involves the identification and ... See full document
9
COVID-19: molecular targets, drug repurposing and new avenues for drug discovery
... until the publication of this manuscript, focusing on COVID-19 treatment interventions (Available from: ...number of patients suffering from acute severe respiratory symptoms and hospital capacities ... See full document
32
Current approaches to immunotherapy in noncolorectal gastrointestinal malignancies
... gastric cancer, limited data relate tumor PD-L1 expres- sion and the objective response rate to ...immunotherapy. In the phase 1b JAVELIN study, patients with tumors with higher expression ... See full document
10
Gene discovery in uterine leiomyoma using cytogenetic approaches
... from the observation that complementary sequences hybridize with higher stability than non‐complementary ...One of the fastest and simplest methods to assess genetic anomalies present in ... See full document
62
Characterization of gastric cancer glycosylation profile for the discovery of biomarkers
... (GI) cancer is the most common group of malignancies and many of its types are among the most ...used in clinical practice as serum biomarker for several GI tumors, however, with ... See full document
217
Averaged differential expression for the discovery of biomarkers in the blood of patients with prostate cancer.
... levels in blood samples from prostate cancer patients (Ca) than in those from healthy men ...to the nucleotide sequence in the ring finger protein 19A (RNF19A) mRNA ...expressed ... See full document
5
FUNCTIONALITY OF UPPER GASTROINTESTINAL CANCER PATIENTS WHICH HAVE UNDERTAKEN SURGERY IN HOSPITAL PHASE
... neoplasia gastrointestinal alta submetidos ao tratamento cirúrgico e analisar os fatores associados às alterações da força e funcionalidade durante o tempo de ...trato gastrointestinal alto submetidos ao ... See full document
5
Immunohistochemistry detection of putative miR-200c and miR-203 Targets in Breast Cancer Patients
... evolution of breast cancer have prompted researchers to find a strategy to classify the disease and to possibly define supportive prognostic and predictive ...on the putative utility of ... See full document
72
Combining Bayesian approaches and evolutionary techniques for the inference of breast cancer networks
... types of models, such as directed graphs, Boolean networks (Akutsu et ...levels of detail and com- plexity. The choice of the model is often determined by how much information it tries ... See full document
8
Long non-coding RNAs as potential therapeutic targets in human breast cancer
... , o que perturba a segregação dos cromossomas durante a mitose e provoca aneuploidia. Por sua vez, a aneuploidia pode contribuir para o ganho de funções por parte de oncogenes e a perda de funções por parte de genes ... See full document
44
Chronology of the discovery of malaria vectors in the Brazilian Amazon.
... [r] ... See full document
8
temas relacionados