[PDF] Top 20 Inhibition of TDP-43 aggregation by nucleic acid binding.
Has 10000 "Inhibition of TDP-43 aggregation by nucleic acid binding." found on our website. Below are the top 20 most common "Inhibition of TDP-43 aggregation by nucleic acid binding.".
Inhibition of TDP-43 aggregation by nucleic acid binding.
... solubility of TDP-43 and proposed that the binding partners/collaborators might help to diminish the intrinsically aggregation-prone tendency in TDP- ...promoted ... See full document
11
Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.
... clearance of mislocalized and misfolded proteins ...proteasome inhibition induced cytoplasmic accumulation of TDP-43 in primary neurons under our experi- mental conditions ...assessed ... See full document
13
M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.
... efficacy of M2e-VLPs produced by the HBc pre- sentation technology ...domain of HBc. This domain is responsible for nucleic acid binding and was shown to prime the mammalian ... See full document
12
The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers.
... hallmark of systemic lupus erythematosus (SLE), a prototypic autoimmune disease characterized by the production of antibodies to components of the cell nucleus (antinuclear antibodies or ANA) ... See full document
7
Immunogenicity Test of Tetanus Component in Adsorbed Vaccines by Toxin Binding Inhibition Test
... duction of vaccines are expensive, toilsome and the re- lease of final results requires several ...production of dT and DTP vaccines shows an excellent consistence of the quality of ... See full document
6
In vitro anti-inflammatory effects of naturally-occurring compounds from two Lauraceae plants
... leaves of Ocotea duckei (Lauraceae) (Morais et ...tract of rats (Jesus-Morais et al. 2000). Thus, as part of our research on the bio- logical activity of Lauraceae compounds, this paper re- ... See full document
6
J. Braz. Chem. Soc. vol.18 número2
... The binding of cetylpyridinium chloride (CPC) with some azo dyes (X6G, 3-BL, DY-42) has been extensively studied at various concentration of dyes, using cetylpyridinium-selective membrane electrode ... See full document
5
Development and Validation of Gold Nanoprobes for Human SNP Detection Towards Commercial Application
... limited by the small size sample (n<1000), heterogeneous genetic background from the candidate genes and difficult in results replication (Rankinen et ...given by this two projects and the development ... See full document
215
Assessment of a two-step nucleic acid amplification assay for detection of Neisseria meningitidis followed by capsular genogrouping
... spite of the recommendation to send frozen samples, bacterial DNA detection was not affected with transport of fresh CSF specimens at room temperature to the Reference ...advantage of real time PCR ... See full document
5
Mechanism of selective VEGF-A binding by neuropilin-1 reveals a basis for specific ligand inhibition.
... capable of sequestering specific ligands are an attractive modality for blocking ligand-dependent signaling path- ...chimera of VEGF receptor (VEGFR), containing the domains necessary for ligand ... See full document
7
Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements.
... Co-occupancy of genes and regulatory sequences by Nipped-B, cohesin, and the TBPH and Lark RNA-binding proteins in BG3 ...detected by PRO-seq [17] are indicated by pink ...average ... See full document
32
Transposable elements in TDP-43-mediated neurodegenerative disorders.
... that TDP-43 broadly targets TE-derived transcripts, including many SINE, LINE and LTR classes as well as some DNA ...between TDP-43 and TE-derived RNA targets is reduced in FTLD patients ... See full document
10
Molecular Staging of Patients with Colon Cancer. The C-Closer-II Study: A Multicentre Study in Portugal
... After surgical extraction, the colectomy specimen was immediately taken to the pathology department. The mesocolon was separated from the colon wall, and fresh LN were harvested from the mesocolic fat within 60 minutes ... See full document
9
The Carbohydrate-binding Specificity and Molecular Modelling of Canavalia maritima and Dioclea grandiflora Lectins
... hydrate-specificity of ConM and DGL towards mono-, di- and trisaccharides reveals some discrep- ancies, as previously shown for other lectins from the Diocleinae sub-tribe (Ayouba et ...sites of ConM and ... See full document
6
From the field to the lab: best practices for field preservation of bat specimens for molecular analyses.
... euthanasia of the animal being sampled. Second, because of its high enzymatic activity, the liver is also the first organ to go through au- tolysis after death ...levels of stress- and ... See full document
12
Menthol binding and inhibition of α7-nicotinic acetylcholine receptors.
... Docking of L-menthol (1R,2S,5R) to the -nACh muscle receptor was performed using the structure of L-menthol (ZINC ID: 01482164) from the ZINC ...regions of the receptor’s molecular surface. ... See full document
12
Heterotrophic prokaryote distribution along a 2300 km transect in the North Pacific subtropical gyre during a strong La Niña conditions: relationship between distribution and hydrological conditions
... sum of their joint effect can ex- plain more than 26 % of the total variation in the LNA dis- tribution, underlying the differences in nutrient utilisation and requirements at the subgroup ...tive of ... See full document
15
Anti-inflammatory and antinociceptive activities of an acid fraction of the seeds of Carpotroche brasiliensis (Raddi) (Flacourtiaceae)
... effects of the C. brasili- ensis seed acid fraction, mice were tested on the rota-rod ...consisted of a horizontal bar 2.5 cm in diameter divided into 5 compartments by disks measuring 25 cm ... See full document
9
A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration.
... a 43-kDa species of TDP-43 is present in FTLD-associated TDP-43 ...aggregated 43-kDa species migrates in SDS-PAGE identically to the physiologically predominant ... See full document
11
A new colorimetric peptide nucleic acid-based assay for the specific detection of bacteria
... similarity of the ...DLs of others methods based on ELISA, which are usually between 105 and 106 CFU/ml [40–43]; or even PNA-FISH, which are approximately 105 CFU/ml ...estimation of the DL ... See full document
16
temas relacionados