[PDF] Top 20 The involvement of the protein Mast in microtubule dynamics and kinetochore-microtubule interactions
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The involvement of the protein Mast in microtubule dynamics and kinetochore-microtubule interactions
... tracking protein, Clasp also localizes to kinetochores, in a microtubule-independent manner, where it starts to accumulate soon after NEBD reaching the highest level during prometaphase while ... See full document
192
The p22HBP heme binding protein: an NMR study of the dynamics and heme-protein interactions
... minute, and 72 ºC for 4 minutes was followed by an extension of 10 min at 72 ...step of was also carried out by running the PCR at 94 ºC for 5 ...controls of sample A and B were ... See full document
233
Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia
... interaction of volatile anesthetics, including halothane, with tubulin and MTs is of great interest both for the mechanism of action of anesthetic gases, and for ... See full document
16
ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics.
... suggesting the possibility of local translation around the ...to the cytoskeleton and the following local translation is shown to be an efficient means of concentrating ... See full document
29
Biochemical characterization of interactions between kinetochore protein complexes
... coild-coil protein that localizes in microtubule plus ends during interphase and to unattached kinetochores during ...This protein is required for silencing the SAC and ... See full document
96
Microtubule Cytoskeleton Remodeling by Acentriolar Microtubule-organizing Centers at the Entry and Exit from Mitosis in Drosophila Somatic Cells
... dispersed in the cytoplasm were found to nucleate MTs de novo as mitotic spindles disassemble and cells transit into G1 stage (Figure ...most of the attention has been focused in ... See full document
13
Non-microtubular localizations of microtubule-associated protein 6 (MAP6).
... MAP6d1-GFP and MAP6d1-myc were ...SDS-PAGE and immunoblotted with each antibody. In the control experiments, COS-7 cells over-expressing either MAP6d1-myc or MAP6d1-GFP were lysed, and ... See full document
24
KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertility.
... upon interactions between germ cells (GC) and supporting somatic ...attachment, the provision of nutrients, and protection from immunological ...cytoskeleton of parallel ... See full document
14
MTB-3, a microtubule plus-end tracking protein (+TIP) of Neurospora crassa.
... part of the cytoskeletal system of all eukaryotic cells and are essential for many vital cellular activities, including maintenance of cell shape, division, migration and ... See full document
9
Chromator is required for proper microtubule spindle formation and mitosis in Drosophila
... issue in interpreting the cause of the Chromator mutant spindle phenotypes is that Chromator at interphase affects chromatin structure (Rath et ...influence the expression of one ... See full document
30
From centrosomal microtubule anchoring and organization to basal body positioning: TBCCD1 an elusive protein
... cilia and flagella are crucial for cell motility of numerous ...composed of nine peripheral dublet microtubules and two single central pair (CP) ...macro- and microcomplexes that ... See full document
77
Virtual and biophysical screening targeting the γ-tubulin complex--a new target for the inhibition of microtubule nucleation.
... are the main constituents of mitotic spindles. They are nucleated in large amounts during spindle assembly, from multiprotein complexes containing c-tubulin and associated c-tubulin complex ... See full document
13
Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice.
... complex and orderly organized MT cytoskeleton, which has been well described on a morphological ...ment and its function in glomerular filtration is still limited. The MT cytoskeleton ... See full document
14
Regulation of retinoschisin secretion in Weri-Rb1 cells by the F-actin and microtubule cytoskeleton.
... GTPases of the Rho family are important regulators of many motile responses that involve the actin cytoskeleton and/or microtubule network ...classes of Rho GTPases, Rho, ... See full document
14
In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.
... note the concern regarding the use of a drug (MG132) to arrest cells at metaphase, this is necessary to trap the cells at metaphase to ensure that the depletion of RCC1 occurs ... See full document
13
The effect of a DeltaK280 mutation on the unfolded state of a microtubule-binding repeat in Tau.
... that in both WT and mutant ensembles residue S285 can adopt Q, y angles consistent with an a-helical/turn ...on the WT sequence are also consistent with these observations as RDC values and ... See full document
12
The involvement of mast cells in the irinotecaninduced enteric neurons loss and reactive gliosis
... activation and gliosis [41, 43]. In fact, under normal basal conditions, only subsets of intestinal enteric glia express GFAP, and most of the enteric glia cells coexpress S100β, ... See full document
13
Co-silencing of human Bub3 and dynein highlights an antagonistic relationship in regulating kinetochore-microtubule attachments
... glance, the question may seem difficult to answer. Indeed, given the role of Bub3, and most probably also of dynein, in promoting end-on attachments, one should expect a rather ... See full document
7
Dynein and MastOrbitCLASP have antagonistic roles in regulating kinetochore-microtubule plus-end dynamics
... In the previous section, we showed that the accumulation of Mast at kinetochores decreases during metaphase and ...either the full-length EGFP-Mast or the ... See full document
11
Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organisation
... If Mast is essential for normal centrosome segregation and bipolar spindles are rarely observed, it might be expected that the spindle checkpoint (Nicklas, 1997) would prevent these cells from ... See full document
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