[PDF] Top 20 Local Fetal Lung Renin Angiotensin System

... that lung hypoplasia and consecutive persistent pulmonary hypertension (PH) associated with this disorder are the key determinants of mortality ...promote fetal lung growth remain an appealing ... See full document

... of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and ...of renin-angiotensin system (RAS) during ... See full document

... Oxidative stress may appear at a very early stage of DN. In cultured cell, the ROS production increased within an hour. Thus we speculate that high glucose stimulation shifts the balance between oxidative and reductive ... See full document

... vation of the tissue RAAS. The authors elegantly demonstrated that during a HSD, Ang-(1-7) had no effect on glomerular filtration rate, whereas the diuresis and natriuresis were attenuated compared with those in rats fed ... See full document

... that local RAS becomes activated in tissues in CHF ...Circulating renin angiotensin system (RAS) in sedentary and exercise-trained Sham and CHF ...A, Angiotensin II; B, ... See full document

... Our results for left ventricle angiotensins show that SHR groups presented increased Ang II levels compared with WC. Classically, RAS is a systematic regulator in various biological activities. Ang II is the key effector ... See full document

... The renin angiotensin aldosterone system (RAAS) is a physiological mechanism which regulates the blood pressure through the modulation of renal vasomotor function, salt and water balance ...[1]. ... See full document

... [33,34,35]. ACE2 overexpression in the heart prevented Ang II- induced cardiac hypertrophy and fibrosis [36,37], while ACE2 gene deletion in mice resulted in cardiac systolic dysfunction and LV wall thinning [38]. ... See full document

... SCr-Verdoppe- lung um 24 % höher als mit Ramipril – dies aufgrund einer signifi kanten Differenz in der Dialyse wegen akuten Nieren- versagens, die in den Endpunkt inkludiert wurde, wohingegen das Risiko einer ... See full document

... Under pathological conditions, an increased activation of the RAAS, especially in the tubular cells, may be observed. A decrease in renal inter‑ stitium iniltration is achieved by blocking the RAAS (antisense ... See full document

... heart, lung and liver were removed and their weights measured and corrected by the body weight of the animal and expressed as heart, lung and liver index ... See full document

... the local RAS from the systemic ...the local Ang II in the heart does not develop hypertrophy; it presents an increase of fibrosis and it develops hypertrophy only when an excess of cardiac Ang II enters the ... See full document

... producing local Ang II ...to local than circulating Ang II [34]. Therefore, local Ang II appears to be more important in the regulation of Ang II-induced ... See full document

... sistema local se caracteriza por la pre- sencia de sus componentes (AGT y las enzimas de conversión), por la síntesis local de Ang II y otros pép- tidos de la Ang, y por su unión a receptores especí- ficos, ... See full document

... of renin and angiotensin II within the PEX syndrome and control groups separately to determine whether the levels originated from local pro- duction or from the blood component, and we could not find ... See full document

... the renin-angiotensin-aldosterone system (RAAS), the sympathetic nervous system, and water-sodium balance system have been widely studied ... See full document

... desartan cilexetil) and an ACE-I (perindopril), under conditions of high (4.0%) and reduced (0.2%) dietary sodium intake. The effect of the combination treatment on the status of the sys- temic RAS in the two sodium ... See full document

... primitive lung epithelium, since early stages of lung development ...murine fetal development, LIF expression was already described in the ureteric bud [15], skin, skeletal muscle, heart, brain, ... See full document

... Beds in CICU and in neonatal ICU were arranged. Upon arrival at the operating room, the patient was asymp- tomatic, in NYHA class II. The following criteria were continu- ously monitored: electrocardiographic trace, ... See full document

... Cuff injury produces a diffuse intimal thickness of artery that is similar to early lesions of atherosclerosis [17]. Huth et al. [28] speculated that medial and adventitial hypoxia induced by closing of the vasa vasorum ... See full document