[PDF] Top 20 Overview of proteomics studies in obstructive sleep apnea

... al., in 2010, applied sypro-ruby-stained 2D- PAGE for the analysis of serum protein signature of patients with different stages of OSA syndrome [57] ...density of the protein spots ... See full document

... impaired in OSA, suggesting a wide range of dysfunction ...Treatment of 10 severe OSA patients with nasal continuous positive air- way pressure (nCPAP) during 4 to 6 months normalized the majority ... See full document

... data in literature, suggesting that male subjects would be prone to presenting OSA and its more severe form due to anatomical factors and/or more impaired ventilatory control during sleep 8,23,29 ... See full document

... changes in heart frequency using HRV rather than baroreceptor ...recordings of barorelex or vagal efferent activity which are supposedly impaired during sleep in severe OSA ...measures ... See full document

... The obstructive sleep apnea (OSA) is one of the most common sleep disorders and is as- sociated with increased risk for obesity, hyperten- sion and cardiovascular ...prevalence ... See full document

... controversial. Sleep deprivation can lead to altered body temper- ature, opiate secretion, and daytime hyper- somnolence, all of which could explain the inhibition of the respiratory center ... See full document

... Previous studies of the effects of vitamin E on cognition and the role of inflammation and oxidative stress in OSA are ...study of 20 patients receiving CPAP therapy found that ... See full document

... patterns in general skill and sequence-specific learning; however the OSA group demonstrated slower RTs in ...are in line with previous studies investigating non-declarative learning in ... See full document

... results of the STOP-BANG questionnaire with a definitive polysomnographic ...use of the STOP-BANG score is used as an instrument to predict the risk of a patient to have OSA may have led to a high ... See full document

... dipping of the blood pressure (BP) reaching about 10–20% of the values recorded during daytime ( Staessen et ...decrease in this physiological BP change is alleged to induce relevant health ... See full document

... between sleep apnea, APOE, and aging disorders related to mental commitment observed in some dementia patients have been ...explanation of assumed mechanistic link between sleep ... See full document

... University of California at Los Angeles (UCLA) Sleep Laboratory, and control subjects from the Los Angeles ...the sleep disorder, and all were recently-diagnosed, as determined by full overnight ... See full document

... dysfunction in OSA ...function in subjects with normal respiration ...effects of these confounding factors when attempting to precisely estimate impairments in parasympathetic nerve ...best ... See full document

... clinical studies suggesting that OSA augments metabolic, inflammatory, autonomic, vascular, and cardiac dysfunction of obesity and exacerbates the metabolic ...OSA in patients with obesity and the ... See full document

... results of this study help to fill the gap of the lack of knowledge of the prevalence by estimating the risk of undiagnosed OSA in obese individuals, although only the risk ... See full document

... presents proteomics data referenced in [1] Using proteomics-based evaluation of red blood cells (RBCs), we have identified differentially abundant proteins associated with Obstructive ... See full document

... evaluated in a sleep clinic diag- nosed with ...by in-laboratory or portable sleep ...difference in ESS score (baseline − retrospective baseline) with the average daily (hours) use ... See full document

... problem in the application of these models is the lack or internal and/or external validation of the results (Leite, ...before sleep) but this made the results not generalizable to use ... See full document

... group of 83 subjects ...appear sleep clinic patients as a whole have elevated ...50% of the OSA patients were treated for hypertension, predominantly with an angiotensin-converting enzyme inhibitor ... See full document

... presents proteomics data referenced in [1] Using proteomics-based evaluation of red blood cells (RBCs), we have identified differentially abundant proteins associated with Obstructive ... See full document