[PDF] Top 20 Tumorigenesis of papillary thyroid cancer is not BRAF-dependent in patients with acromegaly.

... diagnosed patients with acromegaly were referred to Chonnam National University Hwasun Hospital between April 2004 and April ...two patients who presented with inoperable tumors, the ... See full document

... BTG is well recognized (Hanumanthappa et al., 2012). In Gandolfi et ...detection of unsuspected PTC in 14% of BTG patients after postoperative histopathologic examination, and ... See full document

... investigated BRAF mutational status in metastatic and non-metastatic papillary thyroid carcinomas ...have not only found an associa- tion between BRAF-mutation and a more ... See full document

... rate is comparable to rates from other European countries, including Belgium, Italy (25,30,33) and Greece ...vicinity of our medical center and residence of patients to three nuclear plant ... See full document

... (PCLND) is frequently performed in patients with clinically negative central lymph nodes ...applied in patients with T1 and T2 ...benefits of PCLND for CN0 ... See full document

... percentage of BRAF(V600E) alleles defines a PTC molecular subtype and predicts a poorer disease outcome [23,24] and analysis of BRAF mutations by pyrosequencing has recently been demonstrated ... See full document

... miR-26a is down- regulated in PTC [4,5,6,7,8], to date no data have been available regarding the mechanism of miR-26a in this ...growth in an EZH2-dependent manner in ... See full document

... up-regulation of mTOR pathway (25), suggesting that this effect is not tumor-type ...higher in cPTC, although with a preferential cytoplasmic localization. In fact, a decrease ... See full document

... fferentiated thyroid cancer (49), using a dose of 125 mg administered orally once ...(61%) of whom had papillary thyroid carcinoma and 32 (34%) follicular thyroid car- ... See full document

... trial of lenvatinib in RAI-refractory DTC led to complete response in 15% and partial response in 63% of treated ...response with lenvatinib was only 2 months ...therapy ... See full document

... frequency of thyroid cancer in acromegalic patients was ...three patients had not yet undergo­ ne surgery. This frequency is approximately 300 times higher than the ... See full document

... 85% of all thyroid malignancies [2]. Although PTC is considered to be a curable disease with a 10-year-survival rate of more than 90%, disease recurrence is quite common, and a ... See full document

... performed in order to confirm the previous ...absence of breast cancer. These mammograms were performed in the same week when anamnesis and blood samples were ...difference in E 2 ... See full document

... Most of the studies conducted on CTC have compared it to colonoscopy for the detection of polyps and colorectal ...cancer. In a study performed with 1,233 asymptomatic patients, ... See full document

... Hyponatremia is an electrolyte abnormality commonly found in clinical ...It is important to diagnose the underlying etiol- ogy of the hyponatremia and correct it appropriately because severe ... See full document

... The thyroid gland is one of the largest endocrine gland, and comprises two lateral lobes that are connected along the median line by an isthmus, as well as the TPL, which extends superiorly from the ... See full document

... composed of 134 tumours from 125 patients (ten additional tumours were excluded for technical ...files of Hospital de S Jo˜ao/Medical Faculty of Porto, Portugal; IPATIMUP, Porto, Portugal; ... See full document

... differentiated thyroid cancer (DTC) are associated with poor survival ...frequency of this entity, we performed a multicentric retrospective study that aimed to evaluate the presentation, ... See full document

... forms of multiple endocrine neoplasia of dominant autosomal ...nosis of CNC occurs when two major criteria (lentiginoses, primary pigmented nodular adrenocortical disease, cardiac and cutaneous ... See full document

... presence of cervical lymph node metastasis and histological ...associated with recurrence. Expression levels of miR-9 and miR-21 were significantly lower in the recurrent group than in ... See full document