[PDF] Top 20 An updated meta-analysis on the association of MDM2 SNP309 polymorphism with colorectal cancer risk.

... that the MDM2 SNP309 polymorphism might be a risk factor for CRC, the variant genotype was associated with a significant increased CRC risk among the overall ... See full document

... that the use of 5- ASA was associated with a reduced risk of CRN in patients with ...UC. The results also suggested that a higher average daily dose of 5-ASA use ... See full document

... Although the link between DM2 and carcinogenesis was first reported in 1910 by Maynard and Pearson (1910 apud Wojciechowska, 2016) (10), it was over 100 years later that the American Diabetes ... See full document

... in the development and progression of cancer ...in the promoter of COX-2 may exert profound effects on gene transcriptional activity by altering the binding capacity ... See full document

... total of 22 articles were achieved by literature search from PubMed and ...(two with duplicated results, one not focus on ADPRT Val762Ala and APE1 Asp148Glu, and one with lack of usable ... See full document

... Since the outcomes from meta-analysis can be affected by cancer origins, stratified analysis was conducted according to cancer type for the STK15 F31I ... See full document

... was updated on December 20, 2013) using the terms ‘‘p53-binding protein 1 or TP53BP1 or 53BP1’’, ‘‘Asp353Glu or rs560191 or D353E’’, ‘‘cancer or tunor or carcinoma’’ and ‘‘polymorphism, ... See full document

... only the PgRA isoform is expressed and the absence of PgRB is suggested due to the inappropriate cycling of the endometrial gland [25]; however PgRA expression in normal cycling ... See full document

... regulate the immune and antitumor responses in malignancies are good candidates for ...to cancer risk, such as TLRs, ...(PRR) of the innate immune system that recognise a wide variety ... See full document

... in the multistep process of carcinogenesis, and the ERCC5 gene is a vital component of the DNA repair ...deficiency of ERCC5 may result in severe autosomal recessive diseases ... See full document

... for the 2 exon 7 genotype variants, however no significant association was found in mixed ...polymorphisms of CYP1A1 exon 7 polymorphism may be important in specific ethnicity of lung ... See full document

... is an essential enzyme in the BER pathway, which is the primary mechanism for the repair of DNA damage caused by oxidation and alkylation ...[7]. The T1349G polymorphism ... See full document

... The association between T174M polymorphism of angiotensinogen gene and essential hypertension risk remains ...a meta-analysis to achieve a reliable estimation of ... See full document

... investigate the association between ADAM metallopeptidase domain 33 (ADAM33) gene polymorphisms and the risk of childhood ...asthma. The relevant studies about the ... See full document

... calculating the relative risk estimates of cancer in relation to T1DM, no information concerning the potential risk factors for cancer, such as physical inactivity, family ... See full document

... previous meta-analysis conducted by Gao et al suggested the BsmI polymorphism was related to host susceptibil- ity to TB in Asians [16], evidence for overall populations was still ...our ... See full document

... that the Pro12Ala variant would reduce PPARγ ability to stimulate adipogenesis, in vivo studies indicate a more complex sce- nario, with multiple interactions among bio- logical and environmental factors in ... See full document

... aggressiveness of cells in normal or hyperplastic epithelial cells ...Accumulation of DNA damage and lack of response to genotoxic stress contribute to an earlier step in ...1 of TP63, ... See full document

... cascade of host defense mechanisms by inducing the proliferation and differentiation of leucocytes and the secretion of interferons (IFNs), tumor necrosis factor (TNF)-a, antibodies, ... See full document

... total of 10 case-control studies were in- cluded in this ...meta-analysis. The study subjects of 5 studies were Asians, and the other half were ...out the subgroup analy- ... See full document