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Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase.

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Academic year: 2017

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Table 1. Mutation panel found in the dCK coding-sequence in F27-RL and in F10-DL.
Fig 1. Contribution of the individual mutations of G12 to the observed phenotype. Panel A
Fig 2. Scheme of the procedure followed to generate F27-RL and F11-DL. The general structure of the genomic RNAs used for retrovolution is given at the top, on the left for the F16 population and on the right for the population containing only the G12 vari
Fig 3. Position of the mutations found in the individual clones. In each panel, the dCK protein is represented (top of the drawing) as a pale blue box with the main structural motifs given in color (the first and last aminoacid of each motif is given below
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