GWAS identifies novel susceptibility loci on 6p21.32 and 21q21.3 for hepatocellular carcinoma in chronic hepatitis B virus carriers.

The patient has no conditions classically associated with the development of hepatocellular carcinoma (virus infection of hepatitis B and hepatitis C, alcoholism,

Association analysis was performed with 35 mtDNA SNPs in the whole discovery GWAS sample of 1,158 (extremely) obese children and adolescents and 435 lean and normal weight

Indeed, as shown in this study, conventional GWAS identified genome-wide significant SNPs in multiple loci in five out of the eight traits studied in both cohorts that were

Based on these association results, the sum score of SNPs showing the most significant effects (i.e. the number of risk alleles over all SNPs) weighted by the ln(OR) of these

Infection with hepatitis C virus (HCV) affects millions of individuals in the world, resulting in chronic liver disease like chronic hepatitis (CH) and hepatocellular carcinoma

To identify genetic determinants of SCD, genome-wide genotyping and imputation of , 2.5 million SNPs was performed in 1,283 SCD cases and , 20,000 controls drawn from 5 samples

In conclusion, in this study, we confirmed the role of FTO on genetic susceptibility to obesity and discovered two new FTO obesity-related SNPs (rs7206790 and rs11644943), in

A recent genome-wide association study (GWAS) identified five novel susceptibility loci for prostate cancer in the Japanese population.. This study is to replicate and fine map