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636

DOI:

10.1590/0004-282X20150063

IMAGES IN NEUROLOGY

Primary meningeal melanoma with

cerebrospinal fluid dissemination mimicking

neurofibromatosis type 2

Melanoma meníngeo primário com disseminação liquórica mimetizando neurofibromatose

tipo 2

Marcos Rosa Júnior

1

, Luciene Lage da Motta

2

, Fabrizio Scardino

3

A 38-year-old man admitted with headache, left paresis and

bilateral sensorineural hearing loss. Neuroimaging showed a

pe-ripheral frontal tumor with hyperintensity on T1WI and

bilater-al internbilater-al auditory canbilater-al (IAC) lesions. (Figures 1, 2 and 3). he

presence of hyperintensity on T1WI, without fat or hemorrhage

should direct for lesions containing melanin

1

. Resection of the

frontal tumor diagnosed a primary malignant meningeal

mela-noma with cerebrospinal luid dissemination once the patient

has no melanocytic lesions outside the CNS. he melanocytic

lesions ranges from melanocytoma to melanoma

2,3,4,5

.

Malignant

melanoma should be included in the diferential diagnosis of

neoplastic CSF dissemination with bilateral IAC lesions

mim-icking schwannomas in NF2.

1Universidade Federal do Espírito Santo, Seção de Radiologia, Vitoria ES, Brazil;

2Laboratório de Cito e Histopatologia Virchow, Vitoria ES, Brazil;

3Hospital Estadual Jayme Santos Neves, Seção de Neurocirurgia, Serra ES, Brazil.

Correspondence: Marcos Rosa Júnior; Centro de Ciências da Saúde, UFES; Avenida Marechal Campos, 1468; 29043-900 Vitória ES, Brasil; E-mail: marcos.rosa@ufes.br

Conflict of interest: There is no conflict of interest to declare.

Received 26 December 2014; Received in final form 19 February 2015; Accepted 13 March 2015.

Figure 1.

Non-contrast CT showed a right frontal hyperdense

tumor (arrowhead).

Figure 3.

FLAIR showed bilateral IAC lesions (arrowheads)

(A), which increased over the following 30 days (arrowheads)

(B) mimicking bilateral acoustic schwannoma in

neurofibromatosis type 2.

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637

Marcos Rosa Júnior et al. Primary meningeal melanoma

References

1. Ginat DT, Meyers SP. Intracranial lesions with high signal intensity

on T1-weighted MR images: differential diagnosis. Radiographics. 2012;32(2):499-516. http://dx.doi.org/10.1148/rg.322105761

2. Brat DJ, Giannini C, Scheithauer BW, Burger PC. Primary melanocytic

neoplasms of the central nervous systems. Am J Surg Pathol. 1999;23(7):745-54.

3. Roser F, Nakamura M, Brandis A, Hans V, Vorkapic P, Samii M.

Transition from meningeal melanocytoma to primary cerebral

melanoma: case report. J Neurosurg. 2004;101(3):528-31. http://dx.doi.org/10.3171/jns.2004.101.3.0528

4. Bydon A, Gutierrez JA, Mahmood A. Meningeal melanocytoma:

an aggressive course for a benign tumor. J Neurooncol. 2003;64(3):259-63. http://dx.doi.org/10.1023/A:1025628802228

5. Xie ZY, Hsieh KLC, Tsang YM, Cheung WK, Hsieh CH. Primary

Imagem

Figure 3. FLAIR showed bilateral IAC lesions (arrowheads)  (A), which increased over the following 30 days (arrowheads)  (B) mimicking bilateral acoustic schwannoma in

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