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https://doi.org/10.1590/0004-282X20170029

OPINION

Neurological manifestations of Chikungunya

Manifestações neurológicas da Chikungunya

1. Sanitation1 Medical Academic Center, Bangkok Thailand; 2. Hainan Medical University, China;

Correspondence: Beuy Joob; Sanitation1 Medical Academic Center, Bangkok Thailand; Email: [email protected] Conflict of interest: There is no conflict of interest to declare.

Received 06 December 2016; Accepted 09 December 2016. Dear Editor,

he report by Pinheiro et al. on “Dengue infection in the nervous system: lessons learned for Zika and Chikungunya (CHIK) Infection” is very interesting1. he authors mentioned

that “besides the typical clinical picture of CHIKV, atypical man -ifestations of neurological complications have been reported: meningo-encephalitis, meningoencephalo-myeloradiculitis, myeloradiculitis, myelitis, myeloneuropathy, Guillain-Barré syndrome and others. he diagnosis is based on clinical, epi -demiological, and laboratory criteria1”. hey also discussed

the clinical neurological problems due to Zika virus infec -tion. Indeed, the similarity between clinical problems due to CHIKV and other arboviruses (dengue and Zika virus) can be observed. Nevertheless, a number of cases with those virus infections can be mild or asymptomatic.

Focusing on neurological problems due to CHIKV, we would like to share the experience from our setting, a tropical area, in Indochina. In our clinical centers, both dengue and CHIKV infections are common. Unlike den -gue infection, the neurological problems of CHIKV are extremely rare, which is similar to the cases of Zika virus infection. According to a national report in hailand on the conirmed cases of viral encephalitis during 2003–2005, there were no cases due to CHIKV infection2. Also, according to the latest large outbreak in a rural province in hailand, many classical and atypical presentations of CHIKV infec -tion have been observed but there were no patients pre -senting with neurological problems3.

Beuy Joob1, Viroj Wiwanitkit2

References

1. Pinheiro TJ, Guimarães LF, Silva MT, Soares CN. Neurological manifestations of Chikungunya and Zika infections. Arq Neuropsiquiatr. 2016;74(11):937-43. https://doi.org/10.1590/0004-282x20160138

2. Olsen SJ, Campbell AP, Supawat K, Liamsuwan S,

Chotpitayasunondh T, Laptikulthum S et al. Infectious causes of

encephalitis and meningoencephalitis in Thailand, 2003-2005. Emerg Infect Dis. 2015;21(2):280-9. https://doi.org/10.3201/eid2102.140291

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