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J. Braz. Chem. Soc. vol.21 número7

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Academic year: 2018

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Figure  1.  Proposed  structures  for  compounds  1,  [PtCl 2 (dox)],  and  2,  [PtCl 2 (tc)].8899 1010 77 66 121255 11 22 3344OHOHOOH COOCH3 NH 2 O PtDCBA11 Cl ClNCH3H3CH+HO88991010776612125511223344OHOHOOHCOOCH3NH2OPtDCBA11Cl ClOHNCH3H3C+HComplex 1Comple
Figure 2. Correlation between cell growth inhibition and cellular platinum  concentration  after  three-day  incubation  with  equitoxic  compound  concentration
Figure 3. Spectra of solutions containing complex 1 (1.0×10 -4  mol L -1 )  and  increasing  concentrations  of  DNA  in  HEPES  buffer  pH  7.4
Figure 6. Melting curves of CT-DNA (100 µmol L -1 ) at 260 nm in the  absence  and  the  presence  of  1  or 2  at  r  =  0.25
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