Association study
Chiari malformation type I: a case-control association study of 58 developmental genes.
... showed association with P-val- ...the association study under the additive ...displaying association after 10% FDR correction for multiple testing ...
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Genome-wide association study identifies phospholipase C zeta 1 (PLCz1) as a stallion fertility locus in Hanoverian warmblood horses.
... Herein, we report a successful application of Equine SNP50 Genotyping Beadchip and GWAS for stallion fertility, implicating equine PLCz1 as a locus for stallion fertility. The haplotype analysis corroborated the ...
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Genetic association study of common mitochondrial variants on body fat mass.
... genetic association tests might be underpowered to detect obesity related genes using BMI ...genome-wide association study using both BMI (most significant SNP: P = ...
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Genome-wide association study of pancreatic cancer in Japanese population.
... the association study based on 991 cases and 5209 controls (Table ...our study Figure 3. Regional association plots for three pancreatic cancer risk ...
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A genome-wide association study identifies five loci influencing facial morphology in Europeans.
... genome-wide association study for facial shape phenotypes in multiple discovery and replication cohorts, considering almost ten thousand individuals of European descent from several ...our study ...
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Genome-wide association study for sperm motility in pigs
... this study the PorcineSNP60 BeadChip (Illumina, San Diego, CA, USA) was used to help identifying the association between SNP markers and sperm motility in two different pig lines, through a Genome Wide ...
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'Smoking genes': a genetic association study.
... first association study in the field that takes into account the most important polymorphisms that are strong candidates to influence smoking behavior, ...our study are overall valid, as all the ...
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COMT and MAO-A Polymorphisms and Obsessive-Compulsive Disorder: A Family-Based Association Study
... The sample consisted of 783 individuals meeting DSM-IV criteria for OCD, and their biologi- cal parents. The OCD probands were recruited from specialized OCD clinics at Harvard Uni- versity, the University of California- ...
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A genome wide association study of mathematical ability reveals an association at chromosome 3q29, a locus associated with autism and learning difficulties: a preliminary study.
... Each individual was classed as having high or low mathematical ability depending on their General Certificate Standard Exami- nation (GCSE) results for Mathematics. To be included in the study the Mathematics GCSE ...
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Cancer association study of aminoacyl-tRNA synthetase signaling network in glioblastoma.
... We selected 4 different genesets, as published previously [1], to examine the potential association of the ARSs and AIMP1–3 (together referred to as ARSN) with GBM at a systemic level. Briefly, we used the NCI ...
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Efficiency of genome-wide association study in open-pollinated populations
... simulation study which investigated the genetic and statistical properties (average power of QTL detection, FDR and R 2 ) of the nested association mapping (NAM) design currently being implemented in maize ...
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Metabolome-wide association study of neovascular age-related macular degeneration.
... This proof-of-principle study was limited by its sample size. The relatively small number of patients and controls could have allowed a random enrichment of metabolic characteristics in either the NVAMD or control ...
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Genome association study through nonlinear mixed models revealed new candidate
... genome association anal- yses is an unbiased search of the entire genome without any assumptions about the role of a certain gene, the candidate gene approach allows researchers to investi- gate the validity of ...
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Association Study of an AFF1 Gene Polymorphism (rs340630) with Iranian Systemic Lupus Erythematosus Patients
... Methods: A total of 320 patients with SLE and 330 age, sex and ethnically matched healthy control subjects were enrolled in the present study. Both cases and healthy con- trols were genotyped for rs340630 ...
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An association study of FOXO3 variant and longevity
... observational study, we evaluated the relationship be- tween environment factors, oxidative stress status, DNA integrity level, and the association of FOXO3 (rs2802292), SOD2 (rs4880), APOE (rs429358 and ...
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Genome-Wide Association Study of Anthracnose Resistance in Andean Beans (Phaseolus vulgaris).
... Developing common bean cultivars with resistance to anthracnose is one of the most effective ways of controlling this important disease. The identification of sources of resistance as well as understanding the underlying ...
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A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2.
... Rheumatoid arthritis (RA), a chronic autoimmune disorder affecting ,1% of the population, is characterized by immune-cell–mediated destruction of the joint architec- ture. Gene–environment interactions are thought to ...
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Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.
... genome-wide association study (GWAS) identified SNPs in 2,679 T2D cases and 3322 controls in middle-age Han ...The association was accentuated when we repeated analysis with the ...an ...
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Replication of TCF4 through association and linkage studies in late-onset Fuchs endothelial corneal dystrophy.
... genome-wide association study identified common alleles at a locus on chromosome 18 near TCF4 which confer susceptibility to ...validation study for TCF4 using the largest FECD dataset to date (450 ...
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