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Caveolin-1

Caveolar fatty acids and acylation of caveolin-1.

Caveolar fatty acids and acylation of caveolin-1.

... of caveolin-1, we purified caveolin-1 by immunoprecip- Figure ...to caveolin-1, associated with caveolae, and present in CHO ...to caveolin-1 (A), associated with ...

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Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis.

Interaction of caveolin-1 with Ku70 inhibits Bax-mediated apoptosis.

... of caveolin-1 protein expression in colon cancer cells enhances apoptosis induced by 5-FU and ...of caveolin-1 to Ku70 limits the dissociation of Bax from Ku70 and the activation of Bax ...

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Neuronal differentiation dictates estrogen-dependent survival and ERK1/2 kinetic by means of caveolin-1.

Neuronal differentiation dictates estrogen-dependent survival and ERK1/2 kinetic by means of caveolin-1.

... Moreover, caveolin-1, a main constituent of caveolae, endogenously expressed and co-localized with ER-a on plasma membrane, is consistently up-regulated following differentiation and cell growth ...

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Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling.

Pilus phase variation switches gonococcal adherence to invasion by caveolin-1-dependent host cell signaling.

... novel caveolin-interacting protein in the present ...to caveolin-1 complexes in cells infected with strain N927 leading to kinase activation and Akt ...

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Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease.

Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease.

... Caveolin-1 (Cav-1) is a regulatory protein of the arterial wall, but its role in human atherosclerosis remains unknown. We have studied the relationships between Cav-1 abundance, ...

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Microparticle-Induced Activation of the Vascular Endothelium Requires Caveolin-1/Caveolae.

Microparticle-Induced Activation of the Vascular Endothelium Requires Caveolin-1/Caveolae.

... on Caveolin-1 deficient (Cav-1-/-) mice have revealed that loss of Cav-1/caveolae provides protec- tion against the development of several vascular ...

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Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene.

Paired hormone response elements predict caveolin-1 as a glucocorticoid target gene.

... organ. Caveolin-1 was strongly responsive in several organs, and the HRE pair in its upstream region showed increased occupancy by glucocorticoid receptor in response to ...

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Nanoscale imaging of caveolin-1 membrane domains in vivo.

Nanoscale imaging of caveolin-1 membrane domains in vivo.

... Light microscopy enables noninvasive imaging of fluorescent species in biological speci- mens, but resolution is generally limited by diffraction to ~200–250 nm. Many biological pro- cesses occur on smaller length ...

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Sex-dependent expression of caveolin 1 in response to sex steroid hormones is closely associated with development of obesity in rats.

Sex-dependent expression of caveolin 1 in response to sex steroid hormones is closely associated with development of obesity in rats.

... Caveolin-1 (CAV1) is a conserved group of structural membrane proteins that form special cholesterol and sphingolipid-rich compartments, especially in adipocytes. Recently, it has been reported that CAV1 is ...

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SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts.

SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts.

... Activation of p38 MAPK, but not SMAD signaling, mediates augmented proliferative responses to serum in myofibroblasts induced by TGF-β The TGF-β/SMAD pathway is well recognized to mediate growth-inhibitory and tumor-sup- ...

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Correction: Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas.

Correction: Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas.

... This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, prov[r] ...

2

Caveolin-1 expression level in cancer associated fibroblasts predicts outcome in gastric cancer.

Caveolin-1 expression level in cancer associated fibroblasts predicts outcome in gastric cancer.

... representative. Finally, we obtained verbal consent from all the 300 patients. A total of 340 formalin-fixed, paraffin-embedded tissues were obtained from patients diagnosed in the period from July 2005 to February 2012, ...

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Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations.

Fatal cardiac arrhythmia and long-QT syndrome in a new form of congenital generalized lipodystrophy with muscle rippling (CGL4) due to PTRF-CAVIN mutations.

... In conclusion, the diverse clinical spectrum of PTRF-CAVIN deficiency displays the consequences of a quintessential lack of functional caveolae. We have shown that the spectrum mirrors the expression pattern of the gene ...

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Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells.

Further characterisation of the molecular signature of quiescent and activated mouse muscle satellite cells.

... Both caveolin-1 and CTR have been reported to be significantly down-regulated in activated/proliferating satellite cells, with the protein no longer detectable [20,25], while expression of integrin a7 has ...

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Routes and mechanisms of extracellular vesicle uptake

Routes and mechanisms of extracellular vesicle uptake

... To test the role of lipid rafts in EV uptake, a range of inhibitors have been employed. EV uptake was significantly reduced in dendritic cells when EV- producing cells were pre-treated with fumonisin B1 and ...

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IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis.

IGF1R signaling in Ewing sarcoma is shaped by clathrin-/caveolin-dependent endocytosis.

... Receptor endocytosis is critical for cell signaling. IGF1R mediates an autocrine loop that is de-regulated in Ewing Sarcoma (ES) cells. Here we study the impact of IGF1R internalization, mediated by clathrin and ...

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A bioinformatics study concerning structural and functional properties of human caveolin proteins

A bioinformatics study concerning structural and functional properties of human caveolin proteins

... caveolins: caveolin-1, -2 and ...of caveolin-2 and -3 were compared to the experimentally determined structural and functional properties of cave- ...of caveolin-2 and -3 to be predicted and ...

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Cyclophosphamide-Induced Cardiomyopathy

Cyclophosphamide-Induced Cardiomyopathy

... survival in 1 out of 3 patients with severe acute cardiomy- opathy. 12 The evidence for these therapies remains limited, and the mechanism of action is not well understood. In the presence of suspected cardiac ...

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Counting to Nowhere: Social Media Adoption and Use as an Opportunity for Public Scholarship and Engagement

Counting to Nowhere: Social Media Adoption and Use as an Opportunity for Public Scholarship and Engagement

... Quantification is everywhere. 1 Of particular interest to many is the number of social media users of a particular platform. While Ev Williams, Twitter founder, does not “give a shit” that Instagram has more users ...

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Self-efficacy and arthritis disability: An updated synthesis of the evidence base and its relevance to optimal patient care

Self-efficacy and arthritis disability: An updated synthesis of the evidence base and its relevance to optimal patient care

... In light of the increasing role of health behaviors as mediators of health status, and the fact that adults with arthritis are required to often carry out highly complex novel behaviors, but may not be confident to do ...

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