Complement activation
Human factor H-related protein 2 (CFHR2) regulates complement activation.
... inhibited complement activation and reduced Mean values 6 SD of three independent experiments and the molar ratios of factor H (1 = 66 nM) to CFHR2 are ...
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Complement activation-related pseudoallergy in dogs following intravenous administration of a liposomal formulation of meglumine antimoniate
... by complement activation (Szebeni 2005), in a phenomenon aptly called Complement Activation-Related Pseudoallergy ...modulate complement acti- vation and CARPA (Szebeni et ...
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Hepatitis C virus NS3/4A protease inhibits complement activation by cleaving complement component 4.
... the complement system, but the precise mechanisms are not well ...of complement component 4 (C4), composed of subunits C4α, C4 , and C4 , and the role of HCV proteins in complement ...classical ...
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Complement activation in atypical hemolytic uremic syn- drome and scleroderma renal crisis: a critical analysis of pathophysiology
... Further activation of coagula- tion factor II (prothrombin) generates small amount of thrombin ...in complement activation by cleaving C3 into its com- ponents (C3a and ...
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Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats.
... inhibit complement activity in Wistar rat serum in vitro (S2 ...block complement activation in blood, we performed a dosing study in which this peptide was delivered IV into jugular catheterized ...
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Complement activation in atypical hemolytic uremic syndrome and scleroderma renal crisis: a critical analysis of pathophysiology
... the complement system are clarifying the role of comple- ment pathways in the development of atypical hemolytic uremic syndrome and scleroderma renal ...that complement pathways appear to be the unifying ...
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Assembly and activation of alternative complement components on endothelial cell-anchored ultra-large von Willebrand factor links complement and hemostasis-thrombosis.
... the complement components in the ...of complement proteins, we initially studied ULVWF strings and the attachment of complement components that were released exclusively from cultured ECs in the ...
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Human pentraxin 3 binds to the complement regulator c4b-binding protein.
... the complement regulatory activity of C4BP, and C4BP was fully functional as a complement inhibitor when recruited by PTX3 to surfaces ...restricted activation of the classical complement ...
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The role of complement in the early phase of Leishmania (Leishmania) amazonensis infection in BALBc mice
... of complement recovery in the sera by the 7th day of ...of complement at the inoculation site during the early phase of infection could have a role in the control of parasite spreading in BALB/c mice ...
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The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b.
... the complement system which forms the immediate, first defence line of innate ...host complement regulators Factor H from human serum with the secreted and surface exposed Sbi protein, by a—to our ...
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Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.
... B. burgdorferi employs multiple strategies to survive in and persistent in the human host. One central immune evasion strategy is the ability of borreliae to camouflage their surface with host fluid phase ...
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In vitro AND in situ ACTIVATION OF THE COMPLEMENT SYSTEM BY THE FUNGUS Lacazia loboi
... after complement activation for two h. Complement fixation was 84% and 85% with NHS in the presence and absence of patient serum, ...to complement activation by the alternative pathway, ...
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Interpain A, a cysteine proteinase from Prevotella intermedia, inhibits complement by degrading complement factor C3.
... affect activation of complement at the concentration used (data not ...shown). Complement activation was assessed by detecting deposited complement factors using rabbit anti-C1q, ...
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SNAKE ANTIVENOMS: ADVERSE REACTIONS AND PRODUCTION TECHNOLOGY Morais VM (1), Massaldi H (1)
... presently sensitive to horse proteins and at risk for anaphylactic reaction after a second contact. Moreover, horse IgG(T) is highly glycosylated and more immunogenic than other antibody isotypes (2, 38). For patients ...
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Cimex lectularius (Valenzuela et al. 1998) and ho-
... of complement activation are based on an enzymatic amplifying cascade compa- rable to that seen in blood ...The complement fragments C3a, C4a and C5a activate mast cells, which release histamine, ...
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Ancient origins: complement in invertebrates
... A number of tunicates also express lectins that can utilize MASPs to activate complement. Among these are putative ancestors of collagenous lectins comparable to the collectins and ficolins that participate in the ...
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Variability and action mechanism of a family of anticomplement proteins in Ixodes ricinus.
... of complement activation ...the complement system, they increase susceptibility to infections and/or trigger autoimmune-like symptoms ...of complement inhibition would be significantly lowered ...
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HEMODIALYSIS MEMBRANES: PAST, PRESENT AND FUTURE TRENDS
... of complement activation of hemodialysis along with the C3a and C5a ...the complement activation of hemodialysis membrane at different levels with different action ...molar activation ...
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C3b/iC3b deposition on Streptococcus pneumoniae is not affected by HIV infection.
... C4 complement components ...in complement mediated immunity to ...reduced complement activation due to decreased percentage of pneumococcal specific IgG or altered IgG ...of complement ...
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Microbes bind complement inhibitor factor H via a common site.
... To cause infections microbes need to evade host defense systems, one of these being the evolutionarily old and important arm of innate immunity, the alternative pathway of complement. It can attack all kinds of ...
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