Dorsal root ganglion
Oxaliplatin-Induced Peripheral Neuropathy via TRPA1 Stimulation in Mice Dorsal Root Ganglion Is Correlated with Aluminum Accumulation.
... Oxaliplatin is a platinum-based anticancer drug used to treat metastatic colorectal, breast, and lung cancers. While oxaliplatin kills cancer cells effectively, it exhibits several side ef- fects of varying severity. ...
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Rabies Virus Infection of Cultured Adult Mouse Dorsal Root Ganglion Neurons
... Rabies virus targets are mainly located in the central nervous system (CNS). Most pathological effects of this viral infection take place there (Jack- son & Reimer 1989, King & Turner 1993, Mrak & Young ...
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Effects of sciatic nerve transection on ultrastructure, NADPH-diaphorase reaction and serotonin-, tyrosine hydroxylase-, c-Fos-, glucose transporter 1- and 3-like immunoreactivities in frog dorsal root ganglion
... Some differences between frog and rat responses appear to be common. While moderate neuropeptide Y immunoreactivity was found in normal frog DRG, no immunoreaction to this neuropeptide was observed in rat spinal ganglia. ...
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Transcriptomic differential lncRNA expression is involved in neuropathic pain in rat dorsal root ganglion after spared sciatic nerve injury
... After traumatic damage, the peripheral nervous system can regenerate spontaneously by activating the inherent growth ability of neurons, while the central nervous sys- tem cannot do so (1,2). The sciatic nerve is ...
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Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.
... The dorsal root ganglion (DRG) contains cell bodies of primary afferent neurons that transmit sensory information from the periphery to the central nervous ...
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NF-kB mediated CX3CL1 activation in the dorsal root ganglion contributes to the maintenance of neuropathic pain induced in adult male Sprague Dawley rats
... prone position. Laminectomy was performed to expose the left L5 nerve roots and DRG. The autologous NP was harvested from the C2-C3 intervertebral discs and was implanted next to the left L5 nerve root just ...
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TRPV1 channels are functionally coupled with BK(mSlo1) channels in rat dorsal root ganglion (DRG) neurons.
... dosal root ganglion (DRG) cells, which plays a critical physiological role in regulating the “pain” signal transduction pathway in the peripheral nervous ...
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Pharmacological immunomodulation enhances peripheral ner nerve regeneration ve regeneration
... To assess the effect of N-Acetylmuramyl-L-Alanyl-D-Isoglutamine MDP topically administrated on the regenerating peripheral neurons, twelve male C57BL/6J adult mice were equally distributed into three groups. Four mice ...
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Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia.
... between dorsal root ganglion (DRG) or trigeminal ganglion (TG) neurons and dorsal horn (DH) or caudal spinal trigeminal nucleus (CSTN) neurons ...
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Effect of FGF2 and sciatic nerve grafting on ChAT expression in dorsal root ganglia neurons of spinal cord transected rats
... the dorsal root ganglion (DRG) following nervous system injury and peripheral inflammation Trophic factors, such as nerve growth factor (NGF), brain derived neurotrophic factor (BDNF) and ...
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An acid-sensing ion channel that detects ischemic pain
... Figure 7. Slow and persistent adenosine 5'-triphosphate (ATP) modulation of ASIC3-like cur- rents in dorsal root ganglion neu- rons. A, Representative current recordings with changing exter- nal pH ...
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Neuro-vascular-desmal relationship disturbances in peripheral nerves, dorsal root ganglions and motor segmental centers in the etoposide-induced neuropathy.
... adult-rat dorsal root ganglion neurons in culture – quantification of the neurotoxicity of anticancer agents and of its prevention by nerve growth-factor or basic fibroblast growth-factor but not ...
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Estragole blocks neuronal excitability by direct inhibition of Na
... dissociated dorsal root ganglion neurons of rats were used to record action potential and Na + currents with intracellular and patch-clamp techniques, ...
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Caspase-Mediated Apoptosis in Sensory Neurons of Cultured Dorsal Root Ganglia in Adult Mouse
... Fig 1: Morphological features of apoptosis in sensory neurons. Propidium iodide (red) and Hoechst 33342 (blue) staining revealed morphological changes of apoptosis in dorsal root ganglion (DRG) ...
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Diversity among satellite glial cells in dorsal root ganglia of the rat
... of dorsal root ganglion showing the relationship between a large neuron (asterisk) and satellite glial ...of dorsal root ...A dorsal root ganglion neuron (open ...
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Compression of gasserian ganglion and trigeminal root with balloon in the treatment of trigeminal neuralgia: prospective study of 40 patients
... * * Address: Avenida Rodrigues Alves 875, 59020-100 Natal RN , Brasil. Forty patients presenting trigeminal neuralgia underwent Gasserian ganglion and trigeminal roots compression w ith Fogarty’s balloon are ...
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Morphology of sympathetic chain in Saguinus niger
... stellate ganglion was located near to the second thoracic vertebra (Cavalcanti et ...this ganglion is located in dorsolateral surface of the longissimus neck muscle at the level of first and second ...
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Citocinas e dor
... Tumor necrosis factor α, also known as cachectin, is a proinlammatory cytokine produced mainly by monocytes, macrophages, and T-lymphocytes that are abundant in the peritoneum and splanchnic tissue. It is also present in ...
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μ-Opioid receptor antibody reveals tissue-dependent specific staining and increased neuronal μ-receptor immunoreactivity at the injured nerve trunk in mice.
... Neuropathic pain is a debilitating chronic disease often resulting from damage to peripheral nerves. Activation of opioid receptors on peripheral sensory neurons can attenuate pain without central nervous system side ...
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Effects of sciatic nerve transection on glucose uptake in the presence and absence of lactate in the frog dorsal root ganglia and spinal cord
... lactate was added to the incubation medium. It has been demonstrated that the perineurium surrounding the frog DRG contains fewer cell layers and more gaps in these layers than the mammalian perineurium (Matsumoto and ...
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