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Extracellular vesicles

EXTRACELLULAR VESICLES: CLASSIFICATION, FUNCTIONS AND CLINICAL RELEVANCE

EXTRACELLULAR VESICLES: CLASSIFICATION, FUNCTIONS AND CLINICAL RELEVANCE

... For pathological processes development submicrone extracellular vesicles are of the same value as for normal organism functioning. Tumor exosomes launch malignant transformation of stem cells [36], suppress ...

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The Pathogenic Fungus Paracoccidioides brasiliensis Exports Extracellular Vesicles Containing Highly Immunogenic alpha-Galactosyl Epitopes

The Pathogenic Fungus Paracoccidioides brasiliensis Exports Extracellular Vesicles Containing Highly Immunogenic alpha-Galactosyl Epitopes

... of extracellular vesicles in ...brasiliensis vesicles in vivo and the differences in contents that could account for distinct disease outcomes depending on the isolate are sub- jects to be ...by ...

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Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance.

Circular RNAs Co-Precipitate with Extracellular Vesicles: A Possible Mechanism for circRNA Clearance.

... As an additional verification we performed mass spectrometry on each of the EV prepara- tions, which can be used to validate the general protein composition of an EV preparation [17,21]. This enabled identification of ...

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Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

... secreted vesicles can be used to mediate intercellular communication processes by transferring various bioactive molecules, including mRNAs and ...lular vesicles contain RNA molecules and performed a deep ...

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Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis

Lipidomic Analysis of Extracellular Vesicles from the Pathogenic Phase of Paracoccidioides brasiliensis

... brasiliensis extracellular vesicles, namely, Hex-C18:0-OH/d19:2-Cer and ...in vesicles is a glucosylceramide (GlcCer), although we have not determined the hexose ...brasiliensis extracellular ...

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Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance.

Structure and function of ABCG2-rich extracellular vesicles mediating multidrug resistance.

... The frequent emergence of drug resistance phenomena to structurally and functionally unrelated anticancer drugs known as multidrug resistance (MDR) continues to be a major impediment to curative cancer chemotherapy ...

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On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells.

On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells.

... Extracellular vesicles (EVs) including exosomes and microvesicles have attracted consider- able attention in the fields of cell biology and ...individual vesicles are ...

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Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.

Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.

... We previously examined the effect of brain microvascular endothelial cell (MVEC) trans- plantation on rat white matter infarction, and found that MVEC transplantation promoted remyelination of demyelinated axons in the ...

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Clinical application of extracellular vesicles in vascular calcification

Clinical application of extracellular vesicles in vascular calcification

... of extracellular vesicles during the physiological mineralization processes in bones was discovered and reported by and Bonucci (17), and in 1969 by Anderson (16), that originally termed them as matrix ...

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Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

... Recently, extracellular vesicles (EV) have been identified in human breast milk (911) and in bovine milk ...membrane-enclosed vesicles (29), cell death can lead to contamination of the pool of ...

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An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus.

An important role of α-hemolysin in extracellular vesicles on the development of atopic dermatitis induced by Staphylococcus aureus.

... Skin barrier disruption and dermal inflammation are key phenotypes of atopic dermatitis (AD). Staphylococcus aureus secretes extracellular vesicles (EVs), which are involved in AD pathogenesis. Here, we ...

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A Local Delivery System for Extracellular Vesicles to Promote Tissue Regeneration

A Local Delivery System for Extracellular Vesicles to Promote Tissue Regeneration

... The main goal of this thesis was to develop an EV delivery system that could be used for the controlled release of the vesicles upon local administration. In order to develop and test such a system it was ...

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Surface glycosylation profiles of urine extracellular vesicles.

Surface glycosylation profiles of urine extracellular vesicles.

... and vesicles derived from them ...of vesicles [29,30] and the abundant urinary glycoprotein uromodulin (or Tamm-Horsfall protein, (THP)) [39] have been independently ...

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Routes and mechanisms of extracellular vesicle uptake

Routes and mechanisms of extracellular vesicle uptake

... Extracellular vesicles (EVs) are small vesicles released by donor cells that can be taken up by recipient cells. Despite their discovery decades ago, it has only recently become apparent that EVs ...

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Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles

Challenges and perspectives to enhance cattle production via in vitro techniques: focus on epigenetics and cell-secreted vesicles

... Extracellular vesicles are present in different body fluids including seminal plasma, ovarian follicular fluid and uterine fluid (TANNETTA et ...secreted vesicles containing bioactive molecules such ...

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Extracellular vesicle-mediated export of fungal RNA

Extracellular vesicle-mediated export of fungal RNA

... Extracellular vesicles (EVs) play an important role in the biology of various organisms, including fungi, in which they are required for the trafficking of molecules across the cell ...RNA-containing ...

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A prospective highlight on exosomal nanoshuttles and cancer immunotherapy and vaccination

A prospective highlight on exosomal nanoshuttles and cancer immunotherapy and vaccination

... that cancer-originated EVs display marked ability to elicit a rapid tissue growth, while other extracellular vesicles (e.g., DEXOs) can impose tumor suppressor potentials. Thus, it seems that the vesicular ...

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Toward the isolation of exosomes by flow cytometry

Toward the isolation of exosomes by flow cytometry

... of extracellular vesicles divide them in three main classes: exosomes, microvesicles/microparticles/ectosomes and apoptotic ...intraluminal vesicles (ILVs). These intraluminal vesicles contain ...

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A structured growth model for Cynara cardunculus cell suspension

A structured growth model for Cynara cardunculus cell suspension

... of extracellular carbohydrates, in non- limiting conditions, or by consumption of structural bio- mass when sucrose was ...the extracellular medium by a diffusion ...

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Identification of a receptor for extracellular renalase.

Identification of a receptor for extracellular renalase.

... Our data indicate that the early activation of the stress kinase p38 pathway, and not ERK pathway, is crucial in mediating the protection of renalase against cisplatin cytotoxicity. Stress signals activate MAPKs, which ...

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