G1 Phase
Different Donor Cell Culture Methods Can Influence the Developmental Ability of Cloned Sheep Embryos.
... G0/G1 phase were recommended as the ideal nuclear donors in SCNT because they facilitated coordination in the cell cycle of the somatic nuclei and the cytoplasm of oocytes [6, ...G0/G1 phase ...
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Pravastatin induces cell cycle arrest and decreased production of VEGF and bFGF in multiple myeloma cell line
... Multiple myeloma (MM) is a B cell bone marrow neoplasia characterized by inflammation with an intense secretion of growth factors that promote tumor growth, cell survival, migration and invasion. The aim of this study ...
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Rev. bras. farmacogn. vol.25 número3
... via down-regulation of matrix metalloproteinases and inhibition of the phosphoinositide 3-kinase/Akt and nuclear factor-kB signaling pathways (Saitoh et al., 2009; Lee et al., 2012; Wang et al., 2014; Senthilkumar and ...
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HCV core protein-induced down-regulation of microRNA-152 promoted aberrant proliferation by regulating Wnt1 in HepG2 cells.
... obvious G1/S transition (Figure 2B, middle panel), but also promoted colony formation efficacy (Figure 2C, the sixth panel), recapitulating the cell cycle profiles and colony formation-promoting effects mediated ...
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LncRNA HULC mediates radioresistance via autophagy in prostate cancer cells
... Prostate cancer (PCa) is the second leading cause of cancer death in men. Irradiation is one of the available options for treatment of PCa, however, approximately 10–45% of PCa are resistant to irradiation. We aimed to ...
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Alterations in the cell cycle in the cerebellum of hyperbilirubinemic Gunn rat: a possible link with apoptosis?
... Severe hyperbilirubinemia causes neurological damage both in humans and rodents. The hyperbilirubinemic Gunn rat shows a marked cerebellar hypoplasia. More recently bilirubin ability to arrest the cell cycle progression ...
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Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells.
... observed in MDA-MB-231 cells even at 100μM of quercetin treatment. To study the response of cancer cells to quercetin, with respect to different hormone receptors, both the cell lines were treated with a fixed ...
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NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt b-catenin signaling pathway
... In conclusion, we showed that NOP14 was down- regulated in malignant melanoma tissue. NOP14 over- expression suppressed melanoma cell proliferation, arrested the cell cycle at G1 phase, promoted apoptosis, ...
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Identification of G1-regulated genes in normally cycling human cells.
... S phase within a relatively short period where over 95% of the selected cells reenter the cell cycle ...potential G1 regulators which may play essential roles in cell cycle progression, normal growth and ...
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Interaction of the retinoblastoma protein with Orc1 and its recruitment to human origins of DNA replication.
... along G1 phase progression and after Orc1 knock down indicate a mutually exclusive binding of Rb to either Orc1 (early G1) or E2F1 (late G1 and S ...late G1 is consistent with the ...
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Celastrol blocks interleukin-6 gene expression via downregulation of NF-κB in prostate carcinoma cells.
... treatments arrested the cell cycle at the G0/G1 phase, thus attenuating cell proliferation in prostate carcinoma PC-3 cells; moreover, celastrol induced cell apoptosis at higher dosage. Knockdown of IL-6 ...
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Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.
... proliferation phase and led to the cessation of cell division ...G2/M phase and later on, 72 hours after Tet addition, a fraction of the cells underwent apoptosis ...
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Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kappaB activation.
... Carrageenan (CGN) is a high molecular weight sulphated polysaccharide derived from red seaweeds. In rodents, its degraded forms (dCGN) can induce intestinal inflammation associated with macrophage recruitment and ...
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Yuni Wu, Youhua Xu, Yali Shen, Cuicui Wang, Gaili Guo and Tiantian Hu
... The objective of this study was to evaluate the effects of tetramethylpyrazine (TMP) in combination with arsenic trioxide (As 2 O 3 ) on the proliferation and differentiation of HL-60 cells. The HL-60 cells were treated ...
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Rev. bras. farmacogn. vol.22 número3
... Abstract: Monoterpenes have been identii ed as responsible of important therapeutic effects of plant-extracts. In this work, we try to compare the cytotoxic effect of six monoterpenes (carvacrol, thymol, carveol, ...
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Expression of 1N3R-Tau isoform inhibits cell proliferation by inducing S phase arrest in N2a cells.
... sub G1 phase among different tau isoforms ...S phase cell number with a reduced cell number in G1 and G2/M phase, while no significant changes were observed when expression of other tau ...
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Mat. Res.
... sigma phase involved double ...chi phase as nucleation sites, while in the second stage the growth of the precipitates was mainly towards the ferrite ...
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Double Kinetics of Intermetallic Phase Precipitation in UNS S32205 Duplex Stainless Steels Submitted to Isothermal Heat Treatment
... sigma phase involved double ...chi phase as nucleation sites, while in the second stage the growth of the precipitates was mainly towards the ferrite ...
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Os framings da violência sexual infanto-juvenil em webnotícias: estudo de caso no G1 e Folha.com.
... A webnotícia já tem um caráter factual por natureza, ou seja, entra em pauta o que está acontecendo no momento, entretanto, nessa etapa da análise tentamos identificar quais notícias estavam restritas apenas ao fato, sem ...
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Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea
... At this point, it is important to emphasize that the only strategy we used to detect mu- tant genotypes was the observation of gross morphology, of the skin and fur, of the gait and behavior among the G1 and G3 ...
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