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lactic acidosis

Metformin-Associated Lactic Acidosis

Metformin-Associated Lactic Acidosis

... of lactic acidosis (LA) delayed the introduction of metformin into clinical practice in the USA until 1995, and such concerns persist ...metformin-associated lactic acidosis (MALA) can develop ...

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Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors.

Tumor environmental factors glucose deprivation and lactic acidosis induce mitotic chromosomal instability--an implication in aneuploid human tumors.

... with lactic acidosis followed by nutrient restoration significantly increases micronuclei (MNi), nucleoplasmic bridges (NPBs), and nuclear blebs (NBs) in HCT116, 4T1 and MCF-7 cancer ...

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Effect of sodium bicarbonate administration on mortality in patients with lactic acidosis: a retrospective analysis.

Effect of sodium bicarbonate administration on mortality in patients with lactic acidosis: a retrospective analysis.

... metabolic acidosis even though normal pH with metabolic acidosis, because sodium bicarbonate therapy is associated with an improvement in renal function and prevents the progression of chronic kidney ...

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Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis.

Lactate Clearance and Vasopressor Seem to Be Predictors for Mortality in Severe Sepsis Patients with Lactic Acidosis Supplementing Sodium Bicarbonate: A Retrospective Analysis.

... Lactate is a marker for tissue hypoxia. Lactate production results from glycolysis, and it metabolizes by either the liver or the kidney [3, 18]. Lactate production in sepsis increases with glycolysis stimulation or ...

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Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA.

Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA.

... Although lactic acidosis is a prominent feature of solid tumors, we still have limited understanding of the mechanisms by which lactic acidosis influences metabolic phenotypes of cancer ...

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The measurement of urine pH to predict the amount of buffer used in the treatment of acute rumen lactic acidosis in cattle

The measurement of urine pH to predict the amount of buffer used in the treatment of acute rumen lactic acidosis in cattle

... metabolic acidosis when there is a deficiency in the bicarbonate absorption by the ...respiratory acidosis (due to some respiratory disease) and an increase in the blood pCO 2 , which negatively interferes ...

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A perspective on Serum Lactic acid, Lactic Acidosis in a Critical Care Unit

A perspective on Serum Lactic acid, Lactic Acidosis in a Critical Care Unit

... Lactic acidosis is a pathological state diagnosed when the serum concentration of lactate or lactic acid remains persistently at >5mmol/L or greater and signiicant acidemia is noted with blood ...

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Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis

Acid-base balance in sheep with experimentally induced acute ruminal lactic acidosis

... The increase in the number of sheep in recent years is owing to the great adaptability of these animals to adverse environmental conditions and the increase of domestic demand for sheep meat (Gonzaga Neto et al., 2005). ...

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Renal replacement therapies for metformin induced lactic acidosis

Renal replacement therapies for metformin induced lactic acidosis

... of lactic acidosis such as congestive heart failure, liver insufficiency, lung disease, alcohol excess, sepsis, shock, volume depletion, former development of lactic acidosis and in advanced ...

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Melas (mitochondrial, encephalopathy, lactic acidosis and stroke like episodes): relato de um caso.

Melas (mitochondrial, encephalopathy, lactic acidosis and stroke like episodes): relato de um caso.

... Tomografia axial computadorizada revelando extensa calcifi- cação em gânglios da base, dilatação do ventrículo lateral esquerdo e áreas com baixos valores de atenuação na região occipit[r] ...

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Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis

Sodium bicarbonate as prevention of metabolic acidosis in sheep submitted to experimental ruminal acidosis

... Sodium bicarbonate (NaHCO3) is a weak base that bu- ffers the hydrogen ions (Ha et al. 1983) and is used in rumi- nant diets to increase ruminal pH (Kezar & Church 1979). In order to balance the ratios of bacteria, ...

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Metabolic acidosis aggravates experimental acute kidney injury

Metabolic acidosis aggravates experimental acute kidney injury

... Metabolic acidosis (MA) is a frequently encountered acid–base dis- turbance in critically ill patients ...including lactic acidosis, ketoacidosis, rapid volume expansion with saline, renal failure, ...

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Decontamination of Pig Carcasses Using Water Pressure and Lactic Acid

Decontamination of Pig Carcasses Using Water Pressure and Lactic Acid

... the lactic acid treatment had a positive effect by reducing microbial counts on the surfaces of pig ...without lactic acid lowered the mesophilic bacterial and enterobacterial counts on both the ...

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Extracellular acidosis selectively inhibits  coupling induced by carbachol in strips of rat gastric fundus

Extracellular acidosis selectively inhibits coupling induced by carbachol in strips of rat gastric fundus

... pigs, acidosis increased fundic tone and decreased the amplitude of pyloric contractions, but acidosis did not affect duodenal basal tonus (Tournadre et ...that acidosis selectively interfered with ...

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Magnetic resonance imaging detects placental hypoxia and acidosis in mouse models of perturbed pregnancies.

Magnetic resonance imaging detects placental hypoxia and acidosis in mouse models of perturbed pregnancies.

... increases in deoxyhaemoglobin (hypoxia) and decreases in intracellular pH (acidosis). We have demonstrated a potential for this technology to correlate dynamic perfusion related changes with structural alterations ...

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Probiotic properties of endemic strains of lactic acid bacteria

Probiotic properties of endemic strains of lactic acid bacteria

... of lactic acid bacteria (LAB) isolated from various samples of matsun, yogurt and salted cheese from natural farms of Armenia were ...of lactic acid bacteria, isolated from dairy products from natural farms ...

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Isothermal Crystallization Kinetics of Poly(lactic acid) StereocomplexGraphene Nanocomposites

Isothermal Crystallization Kinetics of Poly(lactic acid) StereocomplexGraphene Nanocomposites

... In this case, the lower temperature peak of the double melting peaks can be attributed to melting of sc-crystals of low perfection formed at those higher crystallization temperatures [r] ...

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Biocompatible reinforcement of poly(Lactic acid) with graphene nanoplatelets

Biocompatible reinforcement of poly(Lactic acid) with graphene nanoplatelets

... Poly(lactic acid) (PLA) has great worldwide demand due to versatile applicability in packaging, pharmaceutical, textiles, automotive, biomedical, and tissue engineering [2]. It has been widely investigated for ...

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Use of Food Wastes for the Production of Lactic Silage

Use of Food Wastes for the Production of Lactic Silage

... produce lactic silage from food ...a lactic silage and keep it stable for up to 30 days, which was enough storage time before being sent to a drying process for future use in animal feeding or ...

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Arginine- and Polyamine-Induced Lactic Acid Resistance in Neisseria gonorrhoeae.

Arginine- and Polyamine-Induced Lactic Acid Resistance in Neisseria gonorrhoeae.

... In summary, we have demonstrated lactic acid-mediated, low pH-dependent GC killing, and arginine- and polyamine-induced acid resistance. These observations are consistent with previous findings of increased risks ...

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