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Lyme disease

Severity of chronic Lyme disease compared to other chronic conditions: a quality of life survey

Severity of chronic Lyme disease compared to other chronic conditions: a quality of life survey

... Although the CDC is tracking the spread of Lyme disease, very little data is available about its impact on patient quality of life, healthcare service needs and work capability. The CDC has developed a ...

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Developing a NGS panel for diagnosis of Lyme disease and its co-infections

Developing a NGS panel for diagnosis of Lyme disease and its co-infections

... the disease. Regarding Lyme disease, currently, the antibody-based assays are the only method approved by the United States Food and Drug Administration (FDA) for laboratorial diagnostic tests (55, ...

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Different populations of blacklegged tick nymphs exhibit differences in questing behavior that have implications for human lyme disease risk.

Different populations of blacklegged tick nymphs exhibit differences in questing behavior that have implications for human lyme disease risk.

... We report consistent, pronounced differences in the questing behavior of I. scapularis nymphs from southern origins (SC, NC) compared with nymphs from a northern origin (WI). The northern-derived nymphs were much more ...

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Assessment of the risk of contracting Lyme disease in areas with significant human presence

Assessment of the risk of contracting Lyme disease in areas with significant human presence

... for Lyme disease have been produced by various methods: by detecting the prevalence of borreliae in ixodid ticks (Daniels et ...of Lyme disease ...

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Variable VlsE is critical for host reinfection by the Lyme disease spirochete.

Variable VlsE is critical for host reinfection by the Lyme disease spirochete.

... Many pathogens make use of antigenic variation as a way to evade the host immune response. A key mechanism for immune evasion and persistent infection by the Lyme disease spirochete, Borrelia burgdorferi, ...

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BB0347, from the lyme disease spirochete Borrelia burgdorferi, is surface exposed and interacts with the CS1 heparin-binding domain of human fibronectin.

BB0347, from the lyme disease spirochete Borrelia burgdorferi, is surface exposed and interacts with the CS1 heparin-binding domain of human fibronectin.

... The importance of BB0347 in an infection has not yet been established. In order for an ECM-binding protein to have biological significance, it should be presented on the outer membrane of the Lyme disease ...

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Climate, deer, rodents, and acorns as determinants of variation in lyme-disease risk.

Climate, deer, rodents, and acorns as determinants of variation in lyme-disease risk.

... variable Lyme- disease risk or incidence have tended to focus on one or a small number of potential independent variables, and statistically significant effects of both climate [16–18] and deer [23–25] have ...

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Tick histamine release factor is critical for Ixodes scapularis engorgement and transmission of the lyme disease agent.

Tick histamine release factor is critical for Ixodes scapularis engorgement and transmission of the lyme disease agent.

... Ticks are distributed worldwide and affect human and animal health by transmitting diverse infectious agents. Safe and effective vaccines against most tick-borne pathogens are not currently available. Typical vaccines ...

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Strain-specific variation of the decorin-binding adhesin DbpA influences the tissue tropism of the lyme disease spirochete.

Strain-specific variation of the decorin-binding adhesin DbpA influences the tissue tropism of the lyme disease spirochete.

... Lyme disease spirochetes demonstrate strain- and species-specific differences in tissue ...major Lyme disease spirochete species, Borrelia burgdorferi sensu stricto, ...common Lyme ...

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Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen.

Hyperglycemia Impairs Neutrophil-Mediated Bacterial Clearance in Mice Infected with the Lyme Disease Pathogen.

... low dose streptozotocin (STZ)-treated C57BL/6 mice [39]. STZ is an antibiotic which induces irreversible insulin insufficiency by killing pancreatic β-cells [26]. C57BL/6 mice are readily infected by B. burgdorferi but ...

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Glycophospholipid Formulation with NADH and CoQ10 Significantly Reduces  Intractable Fatigue in Western Blot-Positive ‘Chronic Lyme Disease’  Patients: Preliminary Report

Glycophospholipid Formulation with NADH and CoQ10 Significantly Reduces Intractable Fatigue in Western Blot-Positive ‘Chronic Lyme Disease’ Patients: Preliminary Report

... Lyme disease, the most common vector-borne infection in North America, is characterized by multiple signs and symptoms [1-3, 5, 34, ...some Lyme disease patients are initially diagnosed with ...

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HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.

HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete.

... The Lyme disease spirochete Borrelia burgdorferi must differentially express genes and proteins in order to survive in and transit between its tick vector and vertebrate ...the Lyme disease ...

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Functional Exposed Amino Acids of OSPA as a Candidate for Lyme disease Vaccine

Functional Exposed Amino Acids of OSPA as a Candidate for Lyme disease Vaccine

... Lyme disease is caused by the bacterium Borreliaburgdorferi and is transmitted to humans through the bite of infected black legged ...system. Lyme disease is diagnosed based on symptoms, ...

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Borrelia burgdorferi ANTIBODIES IN DOGS FROM COTIA COUNTY, SÃO PAULO STATE, BRAZIL

Borrelia burgdorferi ANTIBODIES IN DOGS FROM COTIA COUNTY, SÃO PAULO STATE, BRAZIL

... Cotia county is located near from São Paulo city and has a vast wooded area named Atlantic Forest. Epidemiological studies performed at this region, where first cases of Lyme disease in humans had been ...

5

Clinics  vol.62 número4

Clinics vol.62 número4

... When serial serology was done in our patient, the ELISA and WB patterns changed, as the disease got bet- ter. Serologic follow up is very important to confirm LDLS and also to predict clinical prognosis. This is ...

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First record of Borrelia burgdorferi B31 strain in Dermacentor nitens ticks in the northern region of Parana (Brazil)

First record of Borrelia burgdorferi B31 strain in Dermacentor nitens ticks in the northern region of Parana (Brazil)

... So far, the studies regarding the identification of etiologic agents for Lyme disease in Brazil have shown negative results. However, serological diagnoses with posi- tive results have been reported in ...

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Doença de Lyme na região de cabeça e pescoço: implicações para a odontologia

Doença de Lyme na região de cabeça e pescoço: implicações para a odontologia

... Lyme disease (LD) is a systemic inflammatory changes resulting from the direct action of the spirochete Borrelia burgdorferi on the host or indirect damage produced by immune response to this ...of ...

5

Borreliose de Lyme simile: uma doença emergente e relevante para a dermatologia no Brasil.

Borreliose de Lyme simile: uma doença emergente e relevante para a dermatologia no Brasil.

... as Lyme disease-like illness in ...the disease, mainly skin manifestation, is the main diagnostic parameter, while serologic exams only confirm the clinical ...

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Antibodies specific to Borrelia burgdorferi in wild animal workers.

Antibodies specific to Borrelia burgdorferi in wild animal workers.

... The occurrence of serum antibodies to Borrelia burgdorferi in professionals in close contact with wild animals was determined. Seventy eight technicians workers coming from two São Paulo public institutions housing wild ...

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Pupila tônica bilateral como seqüela oftálmica isolada da doença de Lyme: relato de caso.

Pupila tônica bilateral como seqüela oftálmica isolada da doença de Lyme: relato de caso.

... Lyme disease is a multisystemic disorder caused by Borrelia burgdorferi spirochete, transmitted by ...with Lyme disease who developed bilateral tonic pupil as the only remaining ...with ...

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