Myelodysplastic syndrome
Mechanisms of resistance to decitabine in the myelodysplastic syndrome.
... The myelodysplastic syndrome (MDS) encompasses a diverse group of clonal hematopoietic disorders united by ineffective production of blood cells and varying risks of transformation to acute myelogenous ...
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Unrelated Donor Bone Marrow Transplantation for Myelodysplastic Syndrome in Children
... We describe long-term disease-free survival (DFS) after unrelated donor bone marrow transplantation (BMT) for myelodysplastic syndrome (MDS) in 118 patients aged #18 years. Forty-six patients had refrac- ...
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Cytogenetic studies of Brazilian pediatric myelodysplastic syndrome cases: challenges and difficulties in a large and emerging country
... = myelodysplastic syndrome/AML associated with Down syndrome; MLN PDGFRB = myeloid and lymphoid neoplasia with eosinophilia and abnormalities in the PDGFRB gene; RC = refractory cytopenia; RAEB = ...
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Association of loss of heterozygosity with cytogenetic abnormalities in acute myeloid leukemia and myelodysplastic syndrome
... Deletions on chromosomes 5 and 7 are frequently seen in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It is assumed that these deletions indicate loss of tumor suppressor genes on these ...
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Cytogenetic study of Brazilian patients with Myelodysplastic Syndrome (MDS)
... Myelodysplastic syndrome (MDS) represents a heter- ogeneous group of clonal disorders of hematopoietic stem cells characterized by quantitative and qualitative hemato- poietic abnormalities, with cytopenia ...
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Comparison of I-FISH and G-banding for the detection of chromosomal abnormalities during the evolution of myelodysplastic syndrome
... Myelodysplastic syndrome (MDS) patients with a normal karyotype constitute a heterogeneous group from a biological stand- point and their outcome is often ...
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Clonal monosomy of chromosome 21 in a case of myelodysplastic syndrome
... ABSTRACT. This study reports on a cytogenetic inding in a bone marrow examination of a 47-year-old male patient treated in the Hematology and Blood Transfusion Service of the Hospital de Base in São José do Rio Preto, ...
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Association of myelodysplastic syndrome with CD5+, CD23+ monoclonal B-cell lymphocytosis
... 10% to 25% of patients at some time during the course of the disease. Autoimmunity in CLL predominantly targets blood constituents, most commonly red cells. The association of MBL and immune dysfunction is uncertain, ...
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Clinics vol.66 número5
... Contributions: Joa˜o Agostinho Machado-Neto contributed to the selection of patients, carried out all experiments and participated in the writing of the manuscript; Fabiola Traina contributed to the selection of ...
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Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian diaphanous-related Formin mDia1 knockout mice.
... The DIAPH1 gene encoding human mDia1 (located at 5q31.3) lies between the two commonly deleted regions mapped by conventional cytogenetics in myelodysplastic syndrome (MDS) patient samples [8]. 5q- MDS is ...
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Rev. Bras. Hematol. Hemoter. vol.26 número2
... Characteristics and outcomes of 52 patients with myelodysplastic syndrome (MDS) who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) were analyzed. Median age was 30 years (range ...
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Rev. Bras. Hematol. Hemoter. vol.33 número6
... T; Myelodysplastic Syndromes Subcommittee of The Chronic Leukaemia Working Party of European Group for Blood and Marrow Transplantation ...therapy-related myelodysplastic syndrome and acute myeloid ...
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Myelodysplastic syndromes: histopathology as prognostic factor
... 3. Verhoef G.E.G., Pittaluga S., Wolf-Peeters C., Boogaerts M.A. FAB classification of myelodysplastic syndrome: Merits and controversies. Ann Hemmatol. 1995; 71: 3-11. 4. Goasguen J.E., Bennet J.M., Cox ...
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Rev. Assoc. Med. Bras. vol.62 suppl.1
... 21. McClune BL, Weisdorf DJ, Pedersen TL, Tunes da Silva G, Tallman MS, Sierra J, et al. Effect of Age on Outcome of Reduced-Intensity Hematopoietic Cell Trans- plantation for Older Patients With Acute Myeloid Leukemia ...
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J. Bras. Patol. Med. Lab. vol.53 número6
... 5. Gattermann N. Pathophysiological and clinical aspects of iron chelation therapy in MDS. Curr Pharm Des. 2012; 18(22): 3222-34. 6. Ghoti H, Fibach E, Westerman M, Gordana O, Ganz T, Rachmilewitz EA. Increased serum ...
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Altered immunophenotypic features of peripheral blood platelets in myelodysplastic syndromes
... ocytic morphology (75 vs. 59%) and low-risk MDS (78 vs. 52%) had a score of 1.5 or under, although these differences did not reach statistical significance (Table 3). Interestingly, all cases who showed MDS-specific ...
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Rev. Bras. Hematol. Hemoter. vol.34 número4
... of myelodysplastic syndromes, the comet assay can be useful to detect DNA lesion intensity and correlate this with cytogenetic ...with myelodysplastic syndrome (47, XY, +8) classiied as comet class ...
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Presence of new mutations in the TP53 gene in patients with lowrisk syndrome : two case reports
... dysplasia myelodysplastic syndrome according to World Health Organization 2016 and classified as very low-risk by Revised International Prognostic ...dysplasia myelodysplastic syndrome and ...
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Mapeamento dos estudos transversais no PUBMED sobre a associação entre Síndrome de Stevens-Johnson e cegueira: estudo de prevalência
... ("Stevens-Johnson Syndrome"[Mesh] ) OR (Stevens Johnson Syndrome) OR (Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum) OR (Stevens Johnson Syndrome Toxic Epidermal ...
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Rev. bras.oftalmol. vol.74 número6
... Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive ...The syndrome typically presents with a characteristic facial rash (poikiloderma), its diagnostic hallmark, and heterogeneous clinical ...
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