Neuronal nitric oxide synthase.
Increased expressions of ADAMTS-13, neuronal nitric oxide synthase, and neurofilament correlate with severity of neuropathology in Border disease virus-infected small ruminants.
... of neuronal nitric oxide synthase (nNOS), A Disintegrin And Metalloprotease with Throm- bospondin type I repeats-13 (ADAMTS-13), and neurofilament (NF) in the brain tissue in small ruminants ...
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Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.
... a neuronal nitric oxide synthase (nNOS) ...(nitric oxide)- mediated decreases in M2c macrophages lead to a reduction in the muscle fibrosis that is associated with increased ...
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Effects of a neuronal nitric oxide synthase inhibitor on lipopolysaccharide-induced fever
... that nitric oxide (NO) has a thermoregulatory action, but very little is known about the mechanisms ...of neuronal nitric oxide synthase (nNOS) inhibition on ...
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NMDA receptor blockade alters the intracellular distribution of neuronal nitric oxide synthase in the superficial layers of the rat superior colliculus
... Figure 2. Effect of N-methyl-D-aspartate receptor blockade on the intracellular distribution of neuronal nitric oxide synthase. Top, Photomicrographs of histochemical reaction for nicotin- ...
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Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders
... Hippocampal output is increased in affective disorders and is mediated by increased glutamatergic input via N -methyl- D - aspartate (NMDA) receptor and moderated by antidepressant treatment. Activation of NMDA receptors ...
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Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats
... inhibits neuronal nitric oxide synthase in vivo and reduces l-DOPA-induced dyskinesias in a rat model of ...a neuronal nitric oxide synthase inhibitor does not ...
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Expression of neuronal nitric oxide synthase in the developing superficial layers of the rat superior colliculus
... Figure 1. Demonstration of neuronal nitric oxide syn- thase (nNOS) in rat superior colliculus homogenates by immunoblot and enzymatic activity. A, Western blot analysis of nNOS in extracts from the ...
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Neuronal and endothelial nitric oxide synthase gene knockout mice
... the neuronal nitric oxide synthase (nNOS) and endothelial nitric oxide synthase (eNOS) genes has led to knockout mice that lack these ...of nitric oxide (NO) ...
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Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats
... and neuronal NOS (nNOS) were described in different tissues and are collectively referred to as constitutive nitric oxide synthase (cNOS), because these isoforms are constitutively expressed ...
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Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.
... high nitric oxide (NO) levels have been shown to be associated with the severity of CCC in chronic chagasic patients ...[6]. Nitric oxide is an important cytotoxic and cytostatic factor in ...
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Purine nucleotides reduce superoxide production by nitric oxide synthase in a murine sepsis model
... (4). Various studies have also shown that NOS may suf- fer oxidation during situations of intense oxidative stress, and this leads NOS to produce superoxide instead of NO (28,29,32). Another explanation for this ...
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Effect of acute nitric oxide synthase inhibition in the modulation of heart rate in rats
... autonomic control of cardiovascular func- tion (19,20). Recent studies have indicated that changes of NO in the central nervous system may contribute to the regulation of the cardiovascular system by inhibition of the ...
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Nitric oxide synthase activity and endogenous inhibitors in rats recovered from allergic encephalomyelitis
... It is interesting to mention that except for eNOS, the expression of mRNA for both neuronal and inducible NOS isoforms were similar between the EAE-r and control groups. These observations are in partial contrast ...
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like effect of nitric oxide synthase inhibitors and sildenafil against depressivelike behavior in mice
... Nitric oxide synthases comprise a family of three related proteins that modulate diverse biological processes such as neurotransmission, vascular homeostasis and immunological surveillance (Alderton et ...
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Determination of arginase 1 and nitric oxide synthase expression during pregnancy and toxoplasma gondii infection
... Arginase is important in several metabolic pathways because it leads to the synthesis of L-ornithine that can be further metabolized to polyamines (putrescine, spermidine, spermine) via ornithine decarboxylase (ODC) or ...
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Histamine modulates nitric oxide release by microglia and dopaminergic neuronal survival
... in neuronal cell death (Doble, 1999; Andersen, 2004; Witte et ...to neuronal cell death (Duncan and Heales, ...three nitric oxide synthase (NOS) genetically different isoforms: the ...
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Methylmercury intoxication activates nitric oxide synthase in chick retinal cell culture
... of nitric oxide (NO) that has multiple roles in the ...by nitric oxide synthase (NOS) ...isoforms: neuronal (NOS-1), inducible (NOS-2) and endothelial ...
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Endothelial nitric oxide synthase uncoupling as a key mediator of melanocyte malignant transformation associated with sustained stress conditions
... In all experiments the adherent cells were treated with various noncytotoxic concentrations of scavengers or inhibitors. To determine these concentrations, MTT assays were performed with the scaven- gers PTIO and ...
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Inducible nitric oxide synthase and tumor necrosis factor- α
... Since a previous study indicated that the cytokine profiles, especially those of TNF-α and NO, and the resulting disturbances in gastrointestinal transit were different at early (1.5 h) and late (8 h) times after bolus ...
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Nitric oxide synthase isoforms and NF-kappaB activity in normal and osteoarthritic human chondrocytes: regulation by inducible nitric oxide
... inducible nitric oxide (NO) on the regulation of NF-jB activity in human chondrocytes, we evaluated (i) the pattern of expression of the neuronal (nNOS) and inducible (iNOS) NO synthase ...
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