Quantitative proteomics
Determining protein complex connectivity using a probabilistic deletion network derived from quantitative proteomics.
... of quantitative proteomics data from wild-type and deletion strain purifications to build a quantitative deletion-interaction network map and subsequently convert the resulting data into an ...
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Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressor.
... tive proteomics cannot currently detect every protein in mamma- lian cells [25], proteomic analysis of sub-proteomes such as subcellular fractions can increase the proteome coverage by quantitative ...of ...
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Plant SILAC: stable-isotope labelling with amino acids of arabidopsis seedlings for quantitative proteomics.
... comparative quantitative proteomics, which has recently been applied to a number of different eukaryotic ...with quantitative proteomics analyses of seedlings exposed to increased salt ...on ...
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Quantitative proteomics identify novel miR-155 target proteins.
... This study was performed to identify miR-155 target proteins in HEK293T cells using quantitative proteomics and to connect these data to functional annotations. A 48 hour time period after transfection was ...
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Maximum entropy reconstructions of dynamic signaling networks from quantitative proteomics data.
... whose quantitative signal outputs are governed by a large set of coupled nonlinear differential equations, the method detects known interactions with significant ...from quantitative proteomics data ...
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Identification of proteins related to epigenetic regulation in the malignant transformation of aberrant karyotypic human embryonic stem cells by quantitative proteomics.
... shows quantitative data (top panel) and MS/MS spectra (lower panel) of peptides from the LIN28 homolog (LIN28), Rho-associated protein kinase 2 (ROCK2), Borealin (CDCA8), developmental pluripotency associated 4 ...
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iTRAQ-Based Quantitative Proteomics Analysis of Black Rice Grain Development Reveals Metabolic Pathways Associated with Anthocyanin Biosynthesis.
... Proteomics studies are generally conducted to obtain a comprehensive evaluation of pro- teins that respond to a specific environment or treatment, and these investigations provide both quantitative and ...
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Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics.
... these quantitative proteomic experiments, it is possible to identify tens to hundreds of specific protein-protein interactions in a single experiment ...from quantitative affinity purification experiments, ...
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Quantitative Proteomics Analysis of the Hepatitis C Virus Replicon High-Permissive and Low-Permissive Cell Lines.
... two quantitative proteomic methods, label-free (peptide peak area) and labeled ...label-free quantitative analysis to obtain more accurate quantitative ...comprehensive quantitative ...
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Protein profiling in hepatocellular carcinoma by label-free quantitative proteomics in two west African populations.
... peptide matches per protein: 1; maximum protein mass: 250000 Da; primary digest reagent: trypsin; missed cleavages: 1; fixed modifications: Carbamidomethyl (C); variable modifi- cations: Oxidation (M). All protein hits ...
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NEW ULTRASONIC-BASED METHODS IN PROTEOMICS
... Since the sequencing of the human genome, quantification of proteins through mass spectrometry, MS,-based approaches has become an important research topic in chemistry, biology, medicine and even chemical engineering ...
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Challenges in proteome analyses of tropical plants
... spectrometry-based quantitative proteomics analysis: Although widely used, the 2-De technique has limitations when dealing with very large or small proteins, the proteins at the extremes of the pI scale, ...
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Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer.
... free quantitative proteomics for the discovery of potential serum biomarkers for lung cancer, and the usage of Tissue microarray analysis (TMA) and Multiple reaction monitoring (MRM) assays for the ...
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Aging-induced proteostatic changes in the rat hippocampus identify ARP3, NEB2 and BRAG2 as a molecular circuitry for cognitive impairment.
... Disturbed proteostasis as a particular phenotype of the aging organism has been advanced in C. elegans experiments and is also conceived to underlie neurodegenerative diseases in humans. Here, we investigated whether ...
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THE ROLE OF NANOTECHNOLOGY IN CANCER TREATMENT AND DIAGNOSIS
... Concerning cancer diagnosis, the main areas in which nanotechnology is being developed include: early stages cancer detection proteomics; improvement of sensitive and specific nanoplat[r] ...
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A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.
... Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) is in part driven by the tyrosine kinase bcr-abl, but imatinib does not produce long-term remission. Therefore, second-generation ABL inhibitors are ...
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Computerized techniques pave the way for drug-drug interaction prediction and interpretation
... genomics, proteomics, metabolomics and molecular data related to drugs are great resources of information that are available in various molecular and biological databases, which can be used to simulate and ...
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QuAnTITATIVE And QuALITATIVE AnALYSIS
... The quantitative and qualitative analysis presented here gathers Brazilian chicken meat production from five regions (North, Northeast, Central-West, Southeast, and South), collected between 1990 and 2009 from ...
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Quantitative Real Time PCR
... Our results show that supplementation of the two strains of Lactobacillus lowered serum total cholesterol levels, but low density lipoprotein (LDL) and triglyceride levels were not[r] ...
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Rev. Bras. Saude Mater. Infant. vol.10 suppl.2
... mention proteomics, have raised problems for decision-making in professional and academic practice that ur- gently require a strong moral position to be taken - an ethics that takes into account our fellow human ...
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