SH-SY5Y neuroblastoma cells
The TrkAIII oncoprotein inhibits mitochondrial free radical ROS-induced death of SH-SY5Y neuroblastoma cells by augmenting SOD2 expression and activity at the mitochondria, within the context of a tumour stem cell-like phenotype.
... TrkAIII SH-SY5Y cells but not in TrkA SH- SY5Y cells, but was not inhibited by the MAPK inhibitor PD098059 ...TrkA SH-SY5Y cells (this study), adding to ...
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Hydrogen sulfide inhibits A2A adenosine receptor agonist induced β-amyloid production in SH-SY5Y neuroblastoma cells via a cAMP dependent pathway.
... A commercially available direct cAMP enzyme immunoassay kit (Cayman Chemical, USA) was used to examine the involve- ment of cAMP. Briefly, cells were incubated in DMEM containing 0.5% FBS. After treatment with ...
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Cytotoxic and genotoxic evaluation of cotinine using human neuroblastoma cells (SH-SY5Y)
... in SH-SY5Y neuroblastoma cells, as well as genotoxicity re- lated to oxidative stress ...nucleobases. SH-SY5Y neuronal cells were cultured under standard conditions and ...
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LMNA knock-down affects differentiation and progression of human neuroblastoma cells.
... experiments, SH-SY5Y and SMS-KCNR cells were seeded at a density of 5610 3 cells/cm 2 ...day cells were induced to differentiate by 10 mM all-trans retinoic acid (ATRA, named RA ...
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Suppression of Cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.
... To date, several regulatory proteins involved in mitochondrial dynamics have been identified. However, the precise mechanism coordinating these complex processes remains unclear. Mitochondrial chaperones regulate ...
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TDP-43 inclusion bodies formed in bacteria are structurally amorphous, non-amyloid and inherently toxic to neuroblastoma cells.
... into SH- SY5Y neuroblastoma cells was performed using a total protein concentration of ...France). Cells were also transfected with R-phycoerythrin (R-PE), a green fluorescent protein ...
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Design and Synthesis of CNb-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
... in SH-SY5Y neuroblastoma cells via an MTT cell viability assay; Experimental procedures for cholinesterase inhibition assays; Table S3: Acetylcholinesterase (AChE) and butyrylcholinesterase ...
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Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.
... The ER is an organelle of fundamental importance to cell functions as it is the Ca 2+ storage site and where surface and secreted proteins are synthesized, folded and assembled before being transported. Mounting evidence ...
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Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells.
... contrast, SH-SY5Y (SY) neuroblastoma cells co- cultured with ...SY cells were co-cultured with microglia and ...SY cells that were ...myeloid cells-1 ...SY cells ...
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Selegiline increases heme oxygenase-1 expression and the cytotoxicity produced by dopamine treatment of neuroblastoma SK-N-SH cells
... in SH-SY5Y cells treated with dopamine ...expression, cells exposed to dopamine plus selegiline showed higher levels of HO-1 mRNA compared to cells exposed to dopa- mine ...
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Optimization of a multielectrode array (MEA)-based approach to study the impact of Aβ on the SH-SY5Y cell line
... with neuroblastoma (62,64). The SK-N-SH cell line contains cells with three different phenotypes: neuronal (N-type), Schwannian (S-type), and intermediary (I-type) ...type cells are considered ...
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Synthesis and biological evaluation of mono and bis-naphthalimide derivatives against SH-SY5Y, human brain cancer cells
... Due of heterogeneity of this disease, it is a challenge to find the cure for the patients with high risk but also to avoid the overtreatment to the patients with favorable diagnosis. The surgical removal of primary tumor ...
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Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells.
... human neuroblastoma SH-SY5Y, a neuronal-like subline of SK- N-SH cells and overexpressed with each of these miRs (miR144, miR153, miR27a and miR142-5p) ...These cells possess the ...
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Downregulation of survivin by siRNA inhibits invasion and promotes apoptosis in neuroblastoma SH-SY5Y cells
... International Neuroblastoma Staging System, which considers stage, group, and tumor biology, patients are assigned to low-, intermediate-, or high-risk groups ...high-risk neuroblastoma have an extremely ...
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Neuroblastoma de Alto Riesgo en Uruguay. ¿Dónde estamos?
... de neuroblastoma 5,7 ...con neuroblastoma, otros marcadores pronósticos como la pérdida de heterocigocidad del cromosoma 11 o la presencia de mutaciones en alK no se encuentran disponibles actualmente en ...
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PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage.
... of neuroblastoma (NB) cancer cells to chemotherapy and radiation is inhibited by the presence of antioxidants, such as glutathione (GSH), which is crucial in counteracting the endogenous production of ...
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UMTS versus DVB-SH na transmissão de sinais de vídeo
... Given the great need of mobile users being able to access desired content and applications anywhere, anytime, the mobile communication systems have to adapt to the market changes and users’ needs. Television systems are ...
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Membrane-enriched proteome changes and prion protein expression during neural differentiation and in neuroblastoma cells
... PK1-KD cells (Table 2), no interactors with PrP were found and a single experimental interaction between ATP5B and acyl-protein thioesterase 1 (LYPLA1) was reported in all queried ...
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Neuroblastoma com metástase orbitária.
... 3. Shubert EE, Oliver GL, Jaco NT. Metastatic neuroblastoma causing bilateral blindness. Can J Ophthalmol. 1969;4(1):100-3. 4. Schwab M, Shimada H, Joshi V. Neuroblastic tumours of adrenal gland and sympathetic ...
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Protection of neuroblastoma Neuro2A cells from hypoxia-induced apoptosis by cyclic phosphatidic acid (cPA).
... Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator with a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. We have previously shown that cPA significantly ...
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