Tight Junctions
Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells.
... Tight junctions (TJs) regulate the movements of substances through the paracellular path- way, and claudins are major determinants of TJ permeability. Claudin-2 forms high conduc- tive cation pores in TJs. ...
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Downregulation of blood-brain barrier phenotype by proinflammatory cytokines involves NADPH oxidase-dependent ROS generation: consequences for interendothelial adherens and tight junctions.
... In summary, a comprehensive investigation comparing the permeabilizing actions of TNF-a and IL-6 in human brain microvascular endothelial cells is presented, with novel findings confirming how either cytokine can ...
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Escherichia coli STb enterotoxin dislodges claudin-1 from epithelial tight junctions.
... Enterotoxigenic Escherichia coli produce various heat-labile and heat-stable enterotoxins. STb is a low molecular weight heat-resistant toxin responsible for diarrhea in farm animals, mainly young pigs. A previous study ...
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Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells
... The objectives of this study were to determine the effect of tumor necrosis factor alpha (TNF-α) on intestinal epithelial cell permeability and the expression of tight junction proteins. Caco-2 cells were plated ...
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Arq. NeuroPsiquiatr. vol.37 número2
... The capillaries are formed of closely applied endothelial cells which at some zones of contact exhibit specialised, electron dense tight junctions ( F i g. 2) and the tight junctions p[r] ...
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A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells.
... During the submission of the present work, another study has reported a human in vitro model based on the co-culture of human endothelial cells derived from cord blood endothelial progenitor cells with astrocytes [5]. ...
11
Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.
... of tight junction components in desmoplakin null keratinocytes, especially ...of tight junction activity in pemphigus patients, it is noteworthy that an upregulation of claudin 1 was found in Hailey- Hailey ...
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HIV-associated disruption of tight and adherens junctions of oral epithelial cells facilitates HSV-1 infection and spread.
... The tight junctions of oropharyngeal mucosal epithelium have critical barrier functions for protection against paracellular spread of various pathogens, including ...of tight junctions of oral ...
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A distinct mechanism of vascular lumen formation in Xenopus requires EGFL7.
... in tight junctions of EGFL7-depleted em- bryos despite the absence of a visible vascular lumen in need of a ...cell-cell junctions in a timely ...Claudin-5-expressing tight junctions ...
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Clinics vol.64 número11
... shared tight junctions with the internal elastic lamina, suggesting that feeding fresh soy oil to estrogen-deficient rats had protective beneits against any damage caused by estrogen deiciency coupled with ...
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The role of adhesion molecules as biomarkers for the aggressive prostate cancer phenotype.
... another by membrane structures called tight junctions (TJ), adherens junctions (AJ) and desmosomes [2]. Together they maintain the architecture of the epithelium. AJ proteins comprise the cadherin ...
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Permeabilidade intestinal e parâmetros nutricionais e bioquímicos na obesidade
... of tight junctions could result in higher endotoxins or LPS uptake (Cani et al, 2007) and in the activation of the local or systemic immune system (Farhadi et al, 2003a; Hollander, 1999) with production of ...
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Six innexins contribute to electrical coupling of C. elegans body-wall muscle.
... gap junctions of different molecular compositions because the electrophysiological analyses were restricted to selected ventral muscle cells between the neck and vulval ...gap junctions in ...
11
Propriedades eletrônicas de fios quânticos de anisotrópicos e dinâmica de pacotes de onda em monocamada de fósforo negro
... Na introdu¸c˜ao deste trabalho vimos que muitas propriedades importantes de um material podem ser inferidas do seu espectro de bandas de energia, sendo o modelo tight-binding uma das maneiras de obter os valores ...
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Vitronectin increases vascular permeability by promoting VE-cadherin internalization at cell junctions.
... Figure 1. Mult VN promotes VE-cadherin internalization. (A) HUVECs were treated with mult VN (10 mg/mL). Confocal microscopy showed continuous and organized VE-cadherin staining, which is normally observed in ECs at ...
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Efeitos do uso de Decanoato de Nandrolona sobre a junção neuromuscular de ratos em processo de envelhecimento submetidos ao exercício resistido
... Considering that the skeletal muscles associated with the neuromuscular junctions have high plasticity in response to physical activity, and that the indiscriminate [r] ...
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Morfofisiologia do intestino médio de adultos do mosquito não hematófago Toxorhynchites (Lynchiella) theobaldi (Diptera, Culicidae)
... Structure and function of the basal lamina and cell junctions in the midgut epithelium (stomach) of female Aedes aegypti L.. (Insecta, Diptera).[r] ...
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Cálculos de estrutura eletrônica de materiais mediante combinação linear de orbitais atômicos
... m´etodo tight binding foram publicados por Goringe et ...c´alculo tight binding, os valores das integrais s˜ao determinados atrav´es de m´etodos baseados em primeiros ...m´etodo tight binding ab ...
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Análise da recuperação em reservatório de gás com baixa permeabilidade (TIGHT GAS) através do fraturamento hidráulico
... O mercado norte-americano vem sendo a região de maior avanço na exploração, desenvolvimento e produção de reservatórios não convencionais, tendo a nova produção reduzido muito o preço do gás americano. O shale gas (gás ...
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The influence of interhemispheric connections on ongoing and evoked orientation preference maps and spiking activity in the cat primary visual cortex
... 3) Inter- and intrahemispheric long-range connections might serve as a grid preparing primary visual cortex for likely junctions in a larger visual environment enc[r] ...
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