Ulcerative Colitis (UC)
Computer-Aided Prediction of Long-Term Prognosis of Patients with Ulcerative Colitis after Cytoapheresis Therapy.
... Cytoapheresis (CAP) therapy is widely used in ulcerative colitis (UC) patients with moderate to severe activity in Japan. The aim of this study is to predict the need of operation after CAP therapy of UC ...
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Association of TLR5 gene polymorphisms in ulcerative colitis patients of north India and their role in cytokine homeostasis.
... TLR5 is highly expressed in colonic epithelial cells (CECs). The TLR5 ligand, flagellin can modulate the balance between T regulatory and T effecter cells in IBD [7]. Other TLRs can also affect cytokine homeostasis, T ...
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Dysregulation of T cell receptor N-glycosylation: A molecular mechanism involved in ulcerative colitis
... of the MGAT5 gene (that encodes GnT-V enzyme). Interestingly, we consistently observed a reduced MGAT5 mRNA transcription levels in LPLs from UC patients with active disease compared with controls. These results support ...
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Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.
... Ulcerative colitis (UC) is characterized by chronic and relapsing inflammation in the gastrointestinal tract, and mostly affects the colorectal region of the gastrointestinal tract ...
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5-Aminosalicylates reduce the risk of colorectal neoplasia in patients with ulcerative colitis: an updated meta-analysis.
... Up to July 2013, we searched Medline, Embase, Web of Science, Cochrane CENTRAL, and SinoMed of China for all relevant articles on the effect of 5-ASA use on the risk of CRN among patients with UC. Medical subject heading ...
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Associations among body composition, inflammatory profile and disease extent in ulcerative colitis patients
... It is important to emphasize that these patients can- not be considered representative of the population of ulcerative colitis, since they derive from a hospital for individuals in the range of low income ...
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Serum glycan markers for evaluation of disease activity and prediction of clinical course in patients with ulcerative colitis.
... This study first analyzed whole-serum N-glycan profiles in UC patients using Sweetblot, a high-throughput and automated glycomics system that can measure glycans comprehensively and quantitatively. The total amount of ...
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Tumor necrosis factor alpha blocking agents as treatment for ulcerative colitis intolerant or refractory to conventional medical therapy: a meta-analysis.
... active ulcerative colitis who have failed to respond or are poorly responsive to standard pharmacologic forms of treatment with corticosteroids and immunosuppressive agents, therapy with an anti-TNF-a agent ...
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Immunoexpression of cyclooxygenase-1 and -2 in ulcerative colitis
... Ulcerative colitis (UC) is a disease of the colon and rectum character- ized by a nonspecific chronic inflammation mediated by the concerted response of cellular and humoral ...
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The surgical treatment of patients with ulcerative colitis from an university hospital at Natal, Brazil
... ABSTRACT: Introduction: Ulcerative colitis (UC) is a chronic inlammatory disease that affects the rectum and colon, involving periods of exacerbation and remission. A considerable number of patients ...
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A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis.
... In ulcerative colitis (UC), changes occur in the MGL that may alter its protective capacity [8–10]. These include physical changes in the mucus barrier [11], altered mucin gene expres- sion [12] and ...
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Accuracy of faecal calprotectin and neutrophil Gelatinase B-associated Lipocalin in evaluating subclinical inflammation in UlceRaTIVE colitis-the ACERTIVE study
... Overall, the ROC analysis of the FC levels revealed that FC is a good predictor of macroscopic and microscopic activity in asympto- matic UC patients. As cut-off values, and considering the best bal- ance between ...
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Differences in visceral fat and fat bacterial colonization between ulcerative colitis and Crohn's disease. An in vivo and in vitro study.
... Crohn’s disease (CD) is notably characterized by the expansion of visceral fat with small adipocytes expressing a high proportion of anti-inflammatory genes. Conversely, visceral fat depots in ulcerative ...
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CYTOMEGALOVIRUS IN COLORECTAL CANCER AND IDIOPATHIC ULCERATIVE COLITIS
... Cytomegalovirus (CMV) is a genus in the family Herpesviridae that has been associated with gastrointestinal syndromes. In this work we looked for a possible association of CMV infection with colorectal cancer and ...
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Dose Escalation and Healthcare Resource Use among Ulcerative Colitis Patients Treated with Adalimumab in English Hospitals: An Analysis of Real-World Data.
... Tumour necrosis factor-alpha (TNF-α) inhibitors infliximab, adalimumab, and golimumab are approved for the treatment of moderately to severely active ulcerative colitis (UC) in adults who have inadequate ...
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Calprotectin and the Magnitude of Antibodies to Infliximab in Clinically-stable Ulcerative Colitis Patients are More Relevant Than Infliximab Trough Levels and Pharmacokinetics for Therapeutic Escalation
... Although infliximab (IFX) is an efficient therapy for ulcerative colitis (UC) patients, a considerably high rate of therapeutic failures still occurs. This study aimed at a better understanding of IFX ...
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Effect of a polysaccharidic fraction of Agaricus blazei on colorectal carcinogenesis in rats with ulcerative colitis
... (0.48 ± 0.35 to 1.21 ± 0.92). DMH did not influence ulcerative colitis induced by acetic acid and ATF was also not able to interfere with these lesions. On the other hand, treatment with 5 mg/Kg of ATF ...
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Therapeutic effect of adenosine on experimentally induced acute ulcerative colitis model in rats
... acute ulcerative colitis was successfully induced by AA ...acute colitis group treated with saline had 50% disrupted epithelium, widespread leukocytes, and hemorrhage with an increased ...
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Infrequent p53 gene alterations in ulcerative colitis
... in ulcerative colitis which is histologically negative for ...samples. Ulcerative colitis was classified histologically as active (10 cases) and inactive (3 ...In ulcerative ...
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Effects of Cupressus sempervirens extract on the healing of acetic acid-induced ulcerative colitis in rat
... Ulcerative colitis is a chronic inflammatory condition of the colon with an unknown etiology. In this study, we aimed to evaluate the therapeutic effects of Cupressus sempervirens extract on the healing of ...
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