Wild Type
Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.
... SALL2- a member of the Spalt gene family- is a poorly characterized transcription factor found deregulated in various cancers, which suggests it plays a role in the disease. We previously identified SALL2 as a novel ...
16
Diversity of Iberian nucleopolyhedrovirus wild-type isolates infecting Helicoverpa armigera (Lepidoptera: Noctuidae)
... baculovirus wild-type isolates, which are usually formed by a mixture of geno- types in distinct proportions (Muñoz et ...geno- type within the isolate (Vickers et ...
7
Striking differences between knockout and wild-type mice in global gene expression variability.
... example, wild-type and knockout mice might not be matched with respect to genetic background, which might occur most frequently when experimental animals were insufficiently back-crossed to render them ...
7
Host cell transcriptome profile during wild-type and attenuated dengue virus infection.
... the wild-type strain or the attenuated strain is indicated in Table ...pathogenic wild-type ...the wild-type strain Figure ...
12
Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS?
... The 5-phospho-a-D-ribose 1-diphosphate (PRPP) metabolite plays essential roles in several biosynthetic pathways, including histidine, tryptophan, nucleotides, and, in mycobacteria, cell wall precursors. PRPP is ...
13
Investigating the structure and dynamics of the PIK3CA wild-type and H1047R oncogenic mutant.
... The PIK3CA gene is one of the most frequently mutated oncogenes in human cancers. It encodes p110a, the catalytic subunit of phosphatidylinositol 3-kinase alpha (PI3Ka), which activates signaling cascades leading to cell ...
12
Impact of age on the cerebrovascular proteomes of wild-type and Tg-SwDI mice.
... The structural integrity of cerebral vessels is compromised during ageing. Abnormal amyloid (Ab) deposition in the vasculature can accelerate age-related pathologies. The cerebrovascular response associated with ageing ...
15
FACTORS INVOLVED WITH CADMIUM ABSORPTION BY A WILD-TYPE STRAIN OF SACCHAROMYCES CEREVISIAE
... Stationary phase cells, which remove practically all the cadmium from the medium, showed an increased level of intracellular oxidation, while with first exponential phase cells, which ab[r] ...
6
Screening of wild type Streptomyces isolates able to overproduce clavulanic acid
... it showed poor fitting to the experimental data. Baptista Neto et al. (2000) also utilized a Monod-type kinetic model to describe batch experimental data obtained using simulta- neously peptone, soybean flour and ...
10
Kinetic Analysis of in vitro Production of Wild-Type
... Table 2 summarizes the kinetic variables obtained from this work for infected Sf9 and Sf21 cells: including the specific infected growth rate, cell productivity, mean [r] ...
7
ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms
... The interface residues of the ATXN1 at the AXH domain in the crystal structures models of the AXH domain bound to CIC (PDB ID: 4J2L, [ 49 ] and PDB ID: 2 M41, [ 17 ]) are represented in [r] ...
14
Identificação de alterações genéticas ao diagnóstico e correlação com características clínicas e laboratoriais e evolução em pacientes com leucemia mielóide aguda
... Em 2012, Patel et al realizaram análise mutacional de 18 genes em portadores de LMA e identificaram pelo menos uma alteração somática em 97,3% dos pacientes 138 . A FLT3-ITD, a MLL-PTD e mutações no ASXL1 foram ...
158
Brabykinin B1 Receptor Antagonism Is Beneficial in Renal Ischemia-Reperfusion Injury
... Figure 6. B1B2KO renal function and expression of pro and anti-inflammatory molecules. Renal function was estimated by serum creatinine levels measured using the modified Jaffe´ method. At 24 hours of reperfusion, B1B2KO ...
9
Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain.
... from wild-type m1. In comparison with the wild-type m1 protein, the mutant m1 proteins were found to localize less efficiently to intracellular ...
14
Cell surface area and membrane folding in glioblastoma cell lines differing in PTEN and p53 status.
... As seen in Figure 6, the expression of p53 protein varied markedly among the GBM lines. In DK-MG and U87-MG cells, p53 expression was very poor or under the limit of the detection, which is typical for wild ...
13
Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.
... to wild type CD4 T cells for terminating ...5 wild type T cell lines (C57) and the 5 perforin knockout T cell lines (PrfKo) for each experimental ...
8
Syndrome of Hepatic Cirrhosis, Dystonia, Polycythemia, and Hypermanganesemia Caused by Mutations in SLC30A10, a Manganese Transporter in Man
... missense mutation (c.266T>C), which is located in a highly conserved transmembrane region, and one non- sense mutation (c.585del) predicted to lead to the produc- tion of a significantly truncated protein of 213 amino ...
10
Floral vascular patterns of the double-flowered and wildtype morphs of Nigella damascena L. (Ranunculaceae)
... abstract. he perianth of the double-lowered morph of Nigella damascena L. consists of spirally inserted petaloid sepals and sepal-like organs, similar in shape and colour to the petaloid sepals of the ...
8
Aspergillus nidulans cell wall composition and function change in response to hosting several Aspergillus fumigatus UDP-galactopyranose mutase activity mutants.
... (AnugmA::wild type AfugmA) strain had wild type phenotype, indicating these genes had functional ...to wild type and AfugmA-complemented ...
10
Clinics vol.69 número1
... mice, an ITT was performed after six hours of fasting. Mice were injected intraperitoneally with porcine insulin (Xinbai Pharmaceutical, Nanking, China) at 0.75 unit/kg of body weight. Blood glucose was measured from ...
7