Zinc finger
Design, Construction, and Analysis of Specific Zinc Finger
... with zinc finger tools, choosing a target site one should pay attention to the following points: (1) To make mutagenesis occur at target site and a unique site should be ...
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Roles of Candida albicans Gat2, a GATA-type zinc finger transcription factor, in biofilm formation, filamentous growth and virulence.
... C. albicans can grow in several morphological forms including unicellular yeast-form, elongated hyphae and pseudohyphae. The ability of switching between different growth modes is thought to be important for virulence ...
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Zinc finger binding motifs do not explain recombination rate variation within or between species of Drosophila.
... finger protein analyzed at the superfine-scale was significant. This is complicated by the fact that there are hundreds of comparisons and only 16 windows of known recombination, so power to detect significance is ...
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DUF581 is plant specific FCS-like zinc finger involved in protein-protein interaction.
... of zinc finger with variable ...this zinc-finger may be involved in the binding of PRC complex to the target ...clef zinc finger similar to zinc fingers involved in ...
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The zinc finger protein TcZFP2 binds target mRNAs enriched during Trypanosoma cruzi metacyclogenesis
... with zinc finger CCCH motifs. CCCH zinc finger proteins have been shown to be essential to differentiation events in trypanosomatid ...
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Molecular cloning and expression analysis of a zebrafish novel zinc finger protein gene rnf141
... ZNF230 is a novel zinc finger gene cloned by our laboratory. In order to understand the potential functions of this gene in vertebrate development, we cloned the zebrafish orthologue of human ZNF230, named ...
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The LSD1-type zinc finger motifs of Pisum sativa LSD1 are a novel nuclear localization signal and interact with importin alpha.
... four zinc-chelating cysteine residues are involved in binding to zinc ion, and thus are essential for tertiary structure of LSD1- Figure ...LSD1-type zinc finger ...third zinc ...
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Dissection of splicing regulation at an endogenous locus by zinc-finger nuclease-mediated gene editing.
... Sequences governing RNA splicing are difficult to study in situ due to the great difficulty of traditional targeted mutagenesis. Zinc-finger nuclease (ZFN) technology allows for the rapid and efficient ...
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Global and stage specific patterns of Kruppel-associated-box zinc finger protein gene expression in murine early embryonic cells.
... We first updated the list of Ensembl mouse genes encoding for KRAB-ZFPs or KRAB-O proteins by interrogating four protein databases (http://pfam.sanger.ac.uk/, http://www.ebi.ac.uk/ interpro/, ...
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ATL9, a RING zinc finger protein with E3 ubiquitin ligase activity implicated in chitin- and NADPH oxidase-mediated defense responses.
... Recent work has highlighted the ubiquitin-proteasome system (UPS) and its associated E3 ubiquitin ligases as regulators of the plant defense response and it is clear that these proteins play an important part in disease ...
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Estudo da interação do As(III) com modelo "zinc finger" da proteína NCp7 HIV-1 e complexos de Bi(III) e Sb(III) com ligantes contendo 2-mercapto-imidazol
... of zinc from its coordination site in Zn-finger protein can be promoted by other metal species through competitive ...CCHC zinc finger domain of the NCp7 protein of HIV-1 has been carried out ...
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Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.
... CXXC-type zinc finger domains are found in several other proteins with functions related to DNA or chromatin modification, including the histone H3 lysine 4 (H3K4) methyltransferases mixed- lineage ...
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Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 –
... a zinc finger nuclear transcriptional repressor, its DNA binding sequence is 5- TGTCTTATCGAA-3, within which CTTA is the core sequence binding site ...
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Cloning and Characterization of SmZF1, a Gene Encoding a Schistosoma mansoni Zinc Finger Protein
... The zinc fingers are among the most important structural motifs involved in the interaction between proteins and nucleic ...acids. Zinc-binding units such as the Cys 2 His 2 zinc finger domins ...
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The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.
... Present findings demonstrate that ZAS3, a large zinc finger protein, is a critical regulator of bone resorption and controls bone mass via activation of osteoclasts. This is evident from the observations ...
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A C2H2 zinc finger protein FEMU2 is required for fox1 expression in Chlamydomonas reinhardtii.
... (A) Amino acid sequence alignment of FEMU2 3C2H2 domain with its homologous proteins in algae, fungi, and plant. Red letters indicate the conserved amino acid of the C2H2 ZF. Three of th[r] ...
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Myeloid zinc finger 1 (Mzf1) differentially modulates murine cardiogenesis by interacting with an Nkx2.5 cardiac enhancer.
... to zinc fingers 5-13 (black triangle at position -9430 bp) [8,11] in an electromobility shift assay ...to zinc fingers 1-4 (at position 28181 bp) [ 8,11] by EMSA could not be ...
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Expansion and diversification of BTL ring-H2 ubiquitin ligases in angiosperms: putative Rabring7/BCA2 orthologs.
... RING-H2 zinc finger, which is postulated to provide E3 ligase activity, and the hypothesized interaction between BZF and ubiquitin may play a role in Rabring7/BCA2/BTLs stability ...
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Plasmodium yoelii: Identification of a Gene Encoding a Putative ADP-ribosylation Factor-1 GTPase-activating Protein, PyAG1
... The PyAG1 gene, identified by the screening of a Plasmodium yoelii genomic DNA library with a rhoptry-specific Mab, encodes a protein with a zinc finger structure immediately followed by the con- sensus ...
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Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™.
... Meganucleases, Zinc-Finger nucleases or TALE nucleases to accurately generate a double strand break at a specific locus and promote correction by homologous recombination through the insertion of an ...
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