[PDF] Top 20 Aberrant protein synthesis in human HEK293FT cells
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Aberrant protein synthesis in human HEK293FT cells
... Com o objectivo de elucidar os mecanismos de resposta à acumulação de erros durante a síntese proteica e entender como o aumento de proteínas aberrantes pode levar ao desenvolvimento de doenças e degeneração celular, ... See full document
99
Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.
... fallen in reduced clinical use because of toxic side effects and/or frequently reported resis- tance, like chloramphenicol (CAM), is of special ...obstruct protein synthesis via binding to the ... See full document
22
The NIP7 protein is required for accurate pre-rRNA processing in human cells
... NIP7 protein is required for pre-rRNA processing and ribosome biosynthesis ...that in the case of the Pyrococcus abyssi and ...The human NIP7 interacts with Nop132 (43), the putative ortholog of the ... See full document
18
HCV core protein-induced down-regulation of microRNA-152 promoted aberrant proliferation by regulating Wnt1 in HepG2 cells.
... up-regulated in several types of human cancer, including HCV-related HCC ...core protein [24], and recently, its prognostic role in HCV-related HCC has been demonstrated [26], which is ... See full document
9
Contribution of TRNA modifications for proteostasis in human cells
... an aberrant truncated protein ...ELP3 in zebrafish give rise to motor axonal abnormalities, a determinant factor in ALS disorder, and risk-associated ELP3 alleles related to lower brain ELP3 ... See full document
75
Synthesis and cytotoxic evaluation of a series of 2amino against human cancer cells
... synthesized in the laboratory [2] with multiple biological functions in the metabolic cycles of various organisms ...classified in accordance with the aromatic system present in their ... See full document
12
The human adenovirus type 5 E1B 55 kDa protein obstructs inhibition of viral replication by type I interferon in normal human cells.
... kDa protein has been reported to repress transcription of p53-regulated genes via binding to p53 and to contain a repression domain that inhibits transcription of reporter genes when fused to an heterologous ... See full document
15
A fluorescence based sensor assay that monitors general protein aggregation in human cells
... and aberrant proteins, that can constitute up to a third of newly synthesized ...ing in the cytoplasm. Upon transient transfection of a Hsp27- GFP protein in HEK293T cells, cells ... See full document
7
Polyunsaturated Branched-Chain Fatty Acid Geranylgeranoic Acid Induces Unfolded Protein Response in Human Hepatoma Cells.
... (RT-qPCR) Cells were treated with GGA or other compounds, and total RNA was isolated using the Quick- Gene RNA cultured Cell kit S (Wako) with QuickGene-810 (Kurabo, Osaka, ...cDNA Synthesis kit with random ... See full document
20
Effect of Bone Morphogenetic Protein 6 (BMP6) on Chicken Granulose Cells Proliferation and Progesterone Synthesis
... roles in promoting granulose cell proliferation, follicle survival and prevent atresia in mammals (Knight & Glister, ...expressed in oocyte and granulosa cells (GC) and its ovarian ... See full document
8
Identification of proteins related to epigenetic regulation in the malignant transformation of aberrant karyotypic human embryonic stem cells by quantitative proteomics.
... and protein class terms for the set of differentially expressed proteins were represented as follows: the top three biological process categories were metabolic process ...high in normal karyotypic hESCs ... See full document
19
Aberrant expression and secretion of heat shock protein 90 in patients with bullous pemphigoid.
... shock protein 90 (Hsp90) has been implicated in inflammatory responses and its inhibition has proven successful in different mouse models of autoimmune diseases, including epidermolysis bullosa ... See full document
8
Immunoreactive neuropeptides in the cells of human thymus
... hama, 2006). T-cell development is a strictly com- partmentalized multistep process. TECs have been regarded as the main drivers of T-cell diferentia- tion/maturation (Anderson et al., 1996; Takahama, 2006). hey produce ... See full document
8
The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells.
... signaling in human HEK-293 ...TioV-V protein expression was previously shown to control IFN induction by MDA5 and RIG-I through interactions with MDA5 and LGP2, respectively ...confirmed in ... See full document
14
Human NT2D1 cells (ATCC
... roles in human ...involved in the maintenance of cancer stem cells (CSCs) (Liang et ...These cells, identified in various human malignancies (Ignatova et ... See full document
18
Design of a Vitronectin-Based Recombinant Protein as a Defined Substrate for Differentiation of Human Pluripotent Stem Cells into Hepatocyte-Like Cells.
... hepatic cells has not been ...the cells toward ...fusion protein containing the hepa- rin-binding domain of vitronectin ...shown). In addition, hPSCs adhered to surfaces coated with NC(D6E)-Fc ... See full document
17
Intraclonal protein expression heterogeneity in recombinant CHO cells.
... particularly in culture [77], resulting in an enormous diversity of physiological states, which may also have an indirect effect on transgene ...enables cells to adapt to short-lived environmen- tal ... See full document
11
Aberrant gene expression in humans.
... enriched in enhancer and promoter re- gions of aberrantly-expressed ...is in agreement with the findings of [25], in which Montgomery and colleagues reported the identification of the signal of rare ... See full document
20
Thyroid hormone regulates protein expression in C6 glioma cells
... that human glioma cell lines transport thyroid hormone through the plasma membrane ...an in vitro model for the study of glial cell properties. Thus, C6 cells provide means of studying the effects of ... See full document
4
Human umbilical cord blood cells in infarcted rats
... normal human full- term pregnancies without concomitant infectious diseases after written parental informed consent and institutional approval by the UFRJ Review ...of cells required for cryo- preservation ... See full document
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