[PDF] Top 20 Adhesion Molecules as a Therapeutic Target in IBD
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Adhesion Molecules as a Therapeutic Target in IBD
... process in the pathophysiology of inlammatory bowel diseases, including ulcerative colitis ...process in which specialised adhesion and signalling molecules mediate a series of sequential ... See full document
12
New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma.
... signaling in human endothelial cells [4], both directly, and by potentiating VEGF-induced signaling : MFGE8 thus represents another pro-angiogenic molecule in the tumor ...demonstrated in mouse ... See full document
13
Type I interferon: potential therapeutic target for psoriasis?
... Psoriasis is a debilitating skin disease that affects approximately 2% to 3% of the US population. Although originally viewed as a disease primarily caused by dysfunction of keratinocytes, psoriasis is now recognized as ... See full document
14
Adhesion and Co-stimulatory Molecules in the Pathogenesis of Hepatic and Intestinal Schistosomiasis Mansoni
... of adhesion molecules may have biological ...hesion molecules have been demonstrated to block adhesion in vitro and in vivo (Watson et ...shed adhesion mol- ecules may ... See full document
8
Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy
... stress in a number of proteinuric kidney diseases, including diabetic nephropathy ...autophagy in proximal tubular cells, which reabsorb the protein in urinary ...deicient in proximal tubular ... See full document
10
Mitochondrial respiration--an important therapeutic target in melanoma.
... addressed in the context of this study is whether Elesclomol retained its effect at a state when mitochondrial functions were impaired in the melanoma ...explained in two different ways: First, ... See full document
13
Telomerase: a target for therapeutic effects of curcumin and a curcumin derivative in Aβ1-42 insult in vitro.
... strands in the telomere regions, located at the ends of eukaryotic ...three molecules each of human telomerase reverse transcriptase (TERT), telomerase RNA (TR or TERC), and dyskerin (DKC1) ...found ... See full document
9
Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma.
... of adhesion molecules in NMR liver ...protein in NMR liver extract compared to human (Fig ...cell adhesion molecules and thereby cell ...fibroblasts in a so-called ... See full document
20
Einstein (São Paulo) vol.14 número1
... involved in the development of nanocarrier including in its chemical, physical and biological ...and target of nanocarriers. Oncologists in the near future should have specific combinations of ... See full document
5
Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma.
... interacting molecules and the regulatory mechanisms [31,32,38]. However, its role in reactive and neoplastic B lymphocytes has not been ...addressed. In the literature, there is only one article ... See full document
12
Endothelial Function and Cardiovascular Diseases in HIV Infected Patient
... [13,76-78]. In experimental model human endothelial cells treated with ritonavir showed a significant decrease in cell viability and an increase in cytotoxicity in a time- and dose-dependent ... See full document
7
Nutritional Value and Bioactive Compounds Characterization of Plant Parts From Cynara cardunculus L. (Asteraceae) Cultivated in Central Greece
... luteolin-7-O-glucuronide in amounts that depended on genotype and post-harvest processing ...cynarin in cardoon leaves have been also reported by Rouphael et ...concentration. In contrast, Ramos et ... See full document
12
NLK is a novel therapeutic target for PTEN deficient tumour cells.
... enhanced in PTEN deficient cells upon NLK ...cDNA in addition to control (non targeting) siRNA (siCON) or NLK ...siRNA in PTEN deficient ...37uC in a solution containing ... See full document
6
Elzinandes L Azeredo, Sonia MO Zagne, Allan R Alvarenga, Rita MR Nogueira, Claire F Kubelka, Luzia M de Oliveira-Pinto+
... dengue in Brazil has been increasing gradually. In fact, extensive epidemics of DENV 1 and DENV 2 emerged, and after the appearance of DENV 3, recognized in Rio de Janeiro dur- ing 2002, the disease ... See full document
14
Circulating endothelial cells in patients with venous thromboembolism and myeloproliferative neoplasms
... The VTE group consisted of 16 patients, 12 females and 4 males, with a median age of 38 years (range: 22–65 years) who have had at least one venous TE and that have been selected for thrombophilia testing. Venous ... See full document
9
Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders.
... other in the shape of a ...cues. In this test for spatial memory mice tend to enter the maze arm that was explored most recently and remember the order of the arm entry, thanks to their ability to allocate ... See full document
19
From Allergy to Schistosomes: Role of Fc Receptors and Adhesion Molecules in Eosinophil Effector Function
... manuscript in preparation). In situ hybridization confirmed the presence of CD23 mRNA in purified ...isoforms. In situ RT-PCR confirmed that mRNA corresponding to CD23 “a” and “b” isoforms is ... See full document
6
Immunohistochemical expression of E-cadherin and beta-catenin in ameloblastomas and tooth germs
... observed in ameloblastomas and tooth germs were submitted to descriptive ...minutes in a ...Sections in which the primary antibodies were replaced with 1% ... See full document
7
Green Facade As A Prototype Way Of Extending Natural Sphere In A Hyper Dense Urban Context.
... increase in population and sharp decrease in environmental cover in urban ...far in some of the sustainable remedies like using bioclimatic architecture or solar architecture [4], but planting ... See full document
7
NCAM1 Polysialylation
... disease in individuals afflicted with Fatal Familial Insomnia (FFI). In humans, FFI can be caused by a single amino acid change within the prion protein sequence that replaces an aspartate with an ... See full document
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