[PDF] Top 20 An Overview of B-1 Cells as Antigen-Presenting Cells
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An Overview of B-1 Cells as Antigen-Presenting Cells
... B cells have two primary pathways for their activation as APCs, which occurs through BCR or the germline-encoded PAMP receptors ( 40 – 42 ...in B-2 cell activation: (1) the ligation of ... See full document
6
Hepatitis B virus induces IL-23 production in antigen presenting cells and causes liver damage via the IL-23/IL-17 axis.
... mediator of the proinflammatory effects exerted by Th17 cells in many ...hepatitis B virus (HBV) causes liver damage directly through the IL-23 signaling ...expression of both IL-23 and IL-23R ... See full document
15
Fluorescent imaging of antigen released by a skin-invading helminth reveals differential uptake and activation profiles by antigen presenting cells.
... as an aid for attachment but also that it is required for entry into the stratum corneum ...point of infection to aid penetration shown as a thick ring of fluorescent ...lyse cells, or the ... See full document
14
Identification and characterization of host cathepsins and cystatins during tuberculosis and HIV co-infection of antigen presenting cells
... at 1, 4 and 24 h postinfection. (A) Relative quantification of miRNA expression depicted as a heat map with hierarchical clustering performed by ...non-infected cells (Ni) red - Mtb 1 h; blue ... See full document
69
A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy.
... Defining an optimal strategy for vaccine development remains a significant challenge for many ...modifications of LVS in this project failed to improve protection against a virulent ...human cells ... See full document
13
Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes.
... promoters of the regulated genes with an HMM profile constructed from known EBNA-1 binding sequences (Figure ...enrichment of EBNA-1 binding sites in the promoters of genes ... See full document
10
Exosomes released from Mycoplasma infected tumor cells activate inhibitory B cells.
... variety of cells. They are formed by reverse budding of the multivesicular bodies in the late endocytic compartments and are released upon their fusion with the plasma membrane ...composition ... See full document
13
Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch.
... tumor cells, A20 cells, and 4T1 cells were transfected with linearized pAC-neo-OVA [32] or ...transfected cells were selected with G418 (1 mg/ml for pAC-neo-OVA) or hygromycin B ... See full document
12
Antigen-presenting cells represent targets for R5 HIV-1 infection in the first trimester pregnancy uterine mucosa.
... roles of immune cell populations of the decidua (human uterine mucosa during pregnancy) in early pregnancy ...dNK cells are crucial for angiogenesis [21,22] and trophoblast invasion ...immune ... See full document
9
The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells.
... depiction of the GST-EBNA2 fusion proteins ...(GST-E2s). B). IB4 cell lysates were pulled down by similar amounts of each protein bait and resolved on a 4–20% gradient SDS-PAGE ...amounts of ... See full document
16
Prolonged acceptance of skin grafts induced by B cells places regulatory T cells on the histopathology scene
... response of an nB cell-treated animal, 1 week after nB cell injection the animals were immunized in the footpad and 1 week later draining lymph nodes (DLN) were harvested and ...numbers ... See full document
7
Mesenchymal stem cells for the cell-based therapy of type 1 diabetes : an experimental approach
... destruction of beta-cell mass are currently on final clinical trial ...auto- antigen that contributes to the autoimmune reaction in T1D and ...treatment of adult T1D patients with Diapep277 ... See full document
168
B cells expressing IL-10 mRNA modulate memory T cells after DNA-Hsp65 immunization
... presence of B cells is necessary to support the formation of memory after DNA ...T cells develop after the evolution of the adaptive immune ...recognition of the ... See full document
6
Dental follicle cells rescue the regenerative capacity of periodontal ligament stem cells in an inflammatory microenvironment.
... variety of cytokines and factors, including transforming growth factor-b (TGF-b), hepatic growth factor (HGF), prostaglandin E2 (PGE2), IL-10, nitric oxide (NO), indolamine2, 3-dioxygenase (IDO), ... See full document
10
Enhanced cytotoxicity of natural killer cells following the acquisition of chimeric antigen receptors through trogocytosis.
... acquisition of anti-CD19 CARs via trogocytosis improved the cytotoxicity of NK cells against the patient-derived primary B-ALL cells, three samples of bone marrow from ... See full document
8
Low expression of antigen-presenting and costimulatory molecules by lung cells from tuberculosis patients
... levels of CD86 expres- sion with persistence of ...expression of co- stimulatory molecules by dendritic cells in mice mediastinal lymph nodes after intratra- cheal infection by ...lung ... See full document
9
Effect of immunoglobin-like transcript 7 cross-linking on plasmacytoid dendritic cells differentiation into antigen-presenting cells.
... dendritic cells (pDC) are innate immunity effector cells which play a critical role in the transition from innate to adaptive immune ...present an immature phenotype and can differentiate into either ... See full document
9
THE ROLE OF ANTIGEN PRESENTING CELLS IN IMMUNE REGULATION MEDIATED BY REGULATORY T CELLS
... spleens of WT syngeneic mice. Half of the DC were loaded with OVA peptide and labeled with ...2.5mM of CFSE (CFSE lo ). OVA-loaded and HA-loaded DC were then mixed at a 1:1 ratio and ... See full document
138
Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.
... l of cytoplasmic cell fractionation buffer, and the samples were centrifuged again as described ...l of nuclear cell fractionation ...cycles of 20 s each, with 40% of ...concentration ... See full document
15
B cells contribute to heterogeneity of IL-17 producing cells in rheumatoid arthritis and healthy controls.
... as an important proinflammatory cytokine with a critical role in immune defence against extracellular pathogens as well as in the pathogenesis of different autoimmune ...Members of this cytokine ... See full document
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