[PDF] Top 20 APP is a critical protein in spermatogenesis
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APP is a critical protein in spermatogenesis
... morphology is a very important requirement for all routine histological and cytological research, and is done by adequate and appropriate ...material is routinely processed to paraffin wax to ... See full document
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APP Is a Context-Sensitive Regulator of the Hippocampal Presynaptic Active Zone.
... following APP deletion. APP is highly interconnected in all networks analyzed and serves as a hub, implicating that it is important for the structure and function of the entire ...of ... See full document
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Immunoglobulin production is impaired in protein-deprived mice and can be restored by dietary protein supplementation
... food protein and microbiota antigens occur at the level of the gut mucosa. In animal models where this natural stimula- tion is absent, such as germ-free and antigen-free mice, the gut- associated ... See full document
6
LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility.
... HOOK2 is involved in the assembly of a complex containing PCMI and RAB8a, and the initiation of axoneme microtubule extension ...[19]. In contrast to HOOK2 action in primary cilia, however, ... See full document
20
A20 is critical for the induction of Pam3CSK4-tolerance in monocytic THP-1 cells.
... A20 is required for termina- tion of Toll-like receptor-mediated immune responses, which protected mice from endotoxic shock ...[26]. In A20-deficient mice, MyD88-dependent TLR signals drive the activation ... See full document
10
Immunoglobulin production is impaired in protein-deprived mice and can be restored by dietary protein supplementation
... food protein and microbiota antigens occur at the level of the gut mucosa. In animal models where this natural stimula- tion is absent, such as germ-free and antigen-free mice, the gut- associated ... See full document
6
Pore size is a critical parameter for obtaining sustained protein release from electrochemically synthesized mesoporous silicon microparticles
... Mesoporous silicon microparticles (MS-MPs) were prepared by electrochemical etching, thermal stabilization, and milling to reduce the particle sizes. The resulting powder was sorted by sieving. The particles of the ... See full document
12
Is There an App for Everything? Potentials and Limits of Civic Hacking
... describe in a different way is to open a possibility of a different world” Daniel Cefai Observing elections, denouncing ethnic profiling, alerting on leaking roofs… Is there something in ... See full document
25
High Throughput Sequencing Identifies Misregulated Genes in the Drosophila Polypyrimidine Tract-Binding Protein (hephaestus) Mutant Defective in Spermatogenesis.
... involved in one of the caspase activation pathways necessary for spermatid individualization ...transcript in the heph 2 mutant, was previously uncovered in a genetic screen that was designed to ... See full document
15
Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53.
... (MS) is a chronic autoimmune inflammatory disease of the central ner- vous system ...early in the disease course. However, the pathological mechanisms involved in neurodegeneration are poorly ... See full document
17
Enamelin is critical for ameloblast integrity and enamel ultrastructure formation.
... fixed in 4% PFA plus ...embedding in Epon epoxy resin (Cedarlane, Burlington, ON), or were decalcified for immunogold labeling in 8% EDTA over 2 weeks followed by embedding in LR White acrylic ... See full document
13
Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype.
... (AD) is the most common form of dementia affecting 30 million individu- als world-wide ...Age is the greatest risk factor for AD, with the incidence doubling every 5 years after age ...AD is placing ... See full document
10
Mob1, hippo pathway member, is critical for toxoplasma gondii replication
... gondii is an obligate intracellular parasite of great veterinary and medical ...It is able to evade the immune system of the host by converting from rapidly proliferating tachyzoites to latent bradyzoite ... See full document
125
APP and APP phosphorylation in Gα0-induced STAT3 signaling
... total protein quantification method was performed by Pierce’s BCA protein assay kit in an aliquot of the cell lysates, following the manufacturer’s ...assay is the result of two reactions. ... See full document
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A new functional site W115 in CdtA is critical for Aggregatibacter actinomycetemcomitans cytolethal distending toxin.
... CdtA is adhering to ...[7,21]. In addition, mutagenesis methods have been employed to provide more detailed information about the functional sites of the proteins ...immunofluorescence in combination ... See full document
9
Quality-in-use app evaluation: case of a recruitment app for Portuguese SMEs
... are critical for evaluating any application (Carvalho, Lopes, Alexandre and Alturas, ...task in the mobile application. User satisfaction is essential because, when perceived by the implementation ... See full document
9
Phosphorylation-dependent Alzheimer's Amyloid precursor protein (APP) targeting
... located in various subcellular ...reside in a late Golgi compartment (Sambamurti et ...possibly in microdomains known as caveolae (Ikezu et ...or in post-TGN vesicles, and at the plasma ... See full document
273
The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
... same in the CTRs and ...lost in the ...genes in the iKOs, but did not disclose changed transcript levels of factors secreted by the Sertoli cells ...genes in the iKOs were mostly enriched for ... See full document
13
The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.
... results in a significant reduction of RANKL’s ability to induce osteoclastogenesis and expression of osteoclastic genes, including NFATc1, the master regulator of osteoclast differentiation ...ZAS3 in the ... See full document
12
SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans.
... present in the monopolar spindle assembled in sas-1 mutant ...microtubules in these experiments using antibodies against a- tubulin to determine the number of microtubule organizing centers ...S2). ... See full document
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