[PDF] Top 20 Aqueous biphasic systems for the purification and preservation of biologically active compounds

... purification and preservation ...°C, and composed of large and unsymmetrical organic cations and organic or inorganic anions, have been reported as appropriate stabilizing ... See full document

... by the tie-lines data shown in the Supplementary Table ...these, the modification of proteins is usually carried out with amphiphilic poly- mers 42 .... The chemical modification ... See full document

... Within the liquid-liquid extraction approaches, aqueous biphasic systems (ABS) are an environmentally-friendly technique (since they are mainly composed of water) that received ... See full document

... for the separation of a wide range of biologically active substances, such as amino acids, proteins, including enzymes and antibodies, and nucleic acids ...Most of ... See full document

... since the mid-1970s, many studies on the characterization on the biophysiological functions of egg components and the seeking of novel biologically active ... See full document

... years, the use of ABS consisting of two immiscible aqueous phases has emerged as a more biocompatible, environmentally-friendly and economically feasible technique for the ... See full document

... about the purification performance of the investigated PEG-PPG ...However, the need of an acetone precipitation step and subsequent dissolution in a specific buffer may ... See full document

... weight and spatial arrangement. The type and the length of branch chains, and consequently their physical and chemical properties, depend on the microbial producing ... See full document

... with the use of organic solvents, are effective to separate and pre-concentrate compounds of interest ...water/oil biphasic sys- tem has a large disadvantage in its use of ... See full document

... demonstrated the existence of Aqueous Biphasic Systems (ABS) as liquid-liquid extraction techniques ...(35,36). The author showed that a concentrated solution of an ... See full document

... Comparing the anions with carboxyl groups, but not with hydroxyl groups, it appears that [Ch][Lev], with its longer aliphatic chain, is more able to form two phases than ...[Ch][Lev] and [Ch][Glu], with a ... See full document

... Given the promising results obtained and to maximize the enantioseparations afforded by these systems, the ABS composition was ...at the biphasic region of ... See full document

... ABSs and the characteristics and properties of the coexisting ...all the phase formers are quite important when applied DES-based ABS in the partition of different ... See full document

... in the fi eld, the use of organic solvents in the preparation of extracts should be avoided (Blum ...Instead, the use of water has been recommended in allelopathic studies ... See full document

... at the development of self-buffering and benign extraction/separation processes, this work reports a novel class of aqueous biphasic systems (ABS) composed of ionic ... See full document

... resumo Nos últimos anos, terapias à base de anticorpos mono e policlonais têm atraído muita atenção por parte da indústria farmacêutica levando a um aumento da investigação neste campo. A imunoglobulina G (IgG), um dos ... See full document

... extraction of a molecule with ATPS strongly depends on the ability to manipulate the physical/chemical properties of the phases aiming at obtaining high partition coefficients ... See full document

... media and strategies to control the ...Moreover, the highest reported IgG production titer was 27 g/L using human embryonic retinal cells ...productivity the downstream processing equipment ... See full document

... years, the emergence and persistence of bacterial strains with resistance to multiple classes of antibiotics has led to renewed interest in the antimicrobial properties of ...in ... See full document

... complexes of Tc(I) and Re(I) useful for the radiometalation of biologically active ...to the large spectrum of GRP receptor–expressing tumors, the bombesin ... See full document