[PDF] Top 20 Association between XPD (Lys751G1n) Polymorphism and Lung Cancer Risk: A Population-Based Study in Iran

... capacity in patients with lung cancer shows a general defect in DNA repair system, lead- ing to low repair capacity and increase in lung can- cer risk (8, ... See full document

... this study, we conducted a comprehensive literature search in different databases and included several additional studies, which allowed for a larger number of subjects (17 studies including 4198 ... See full document

... anomaly and cancer may have some shared genetic and/or environmental fac- tors that may influence the risk of ...on cancer risk ...role in the etiology of cancer ... See full document

... Val762Ala polymorphism in overall cancer risk ...absent in the two previous meta- analysis, the current meta-analysis is the most comprehensive study that has evaluated the ... See full document

... component in transcription factor IIH (TFIIH) complex. XPD helicase plays a pivotal role in unwinding DNA at the damaged region during nucleotide excision repair (NER) ...Dysfunctional XPD ... See full document

... relationship between GERD and lung ...2003) and further result in malignant transformation. In addition, based on the studies investigating the pathogenesis of Barrett’s ... See full document

... involved in EGF gene regulation. In September 2011, at the European Multidisciplinary Cancer Congress, in Stockholm, the association between EGF+61A/G polymorphisms and ... See full document

... rs1800629 polymorphism was associated with OA risk among Caucasian ...gene in Asian populations, we conducted a hospital-based case-control study involving 257 knee OA patients ... See full document

... Polymorphisms in the nicotinic acetylcholine receptor subunit CHRNA5 gene have been associated with lung cancer positive susceptibility in European and American ...populations. ... See full document

... increased risk of colorectal cancer in men, but not in women, with ...women in our study cohort were aged over 55 years, among which no association between obesity ... See full document

... major risk factor of lung ...cases and controls, however only ten eligible publications provided non-smokers ...increased risk was found to be associated with the CYP1A1 exon 7 gene polymor- ... See full document

... controls and sample size. When studies were stratified by source of controls and sample size, we conducted heterogeneity test to explore the source of heterogeneity (Table ...the association ... See full document

... our study included its use of population-based data that are highly representative of the general ...history, and family history, all of which may be risk factors for lung ... See full document

... generated, and a risk of brain stroke reasonably increased ...irradiated in patients with lung cancer and Hodgkin’s lymphoma [6]; however, clinical data are largely lacking ... See full document

... factor in the multistep process of carcinogenesis, and the ERCC5 gene is a vital component of the DNA repair ...result in severe autosomal recessive diseases including XP, CS and TTD [14] ... See full document

... Reviews and Meta-Analyses (PRISMA) [25] and Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines [26], we using the search terms rs402710, ...with lung cancer, ... See full document

... expression and functions of miRNA ...SNPs in miRNA genes, including pri- miRNAs, pre-miRNAs and mature miRNAs, could potentially influence the function of miRNA ...expression and maturation of ... See full document

... recruited between 2013 and 2015, who were followed up in the mastology sector of the division of gynecology of the Faculdade de Medicina do ABC ...breast cancer (case group) and 245 ... See full document

... enzyme in the BER pathway, which is the primary mechanism for the repair of DNA damage caused by oxidation and alkylation ...T1349G polymorphism is the most common polymorphism that result ... See full document

... In Iran, due to mothers’ fear of natural childbirth and the encouragement of gynecology and obstetrics specialists for financial reasons, the cesarean section has become more planned than an ... See full document