[PDF] Top 20 Circulating MicroRNAs as Non-Invasive Biomarkers for Early Detection of Non-Small-Cell Lung Cancer.

... comparisons of study variables between cases and controls used the Chi-squared test for categorical data, and the Student's t-test for continuous ...(IQR) of less than ...P-values of less than ... See full document

... observation of the presence of extracellu- lar nucleic acids in humans ...in cell-free nucleic acids isolated from all different body fluids ...development of malignant tu- ...hallmark ... See full document

... are small non-coding RNAs that regulate various biological ...processes. Cell-free miRNAs measured in blood plasma have emerged as specific and sensitive markers of physiological processes and ... See full document

... power of this arm of the ...in early-stage NSCLC tumors, and reported that patients with a greater EGFR mutation frequency were more sensitive to EGFR-TKIs and showed longer progression-free survival ... See full document

... Squamous cell lung cancer (SCC) and adenocarcinoma are the most common histological subtypes of non-small cell lung cancer (NSCLC), and have been ... See full document

... ung cancer leads to death including both man & woman ...in early diagnosis of lung cancer in ...risk of most redundant outcome of this disease (death) can be minimized ... See full document

... procedure of percutaneous cryoablation was performed under local anesthesia as previously described ...consisted of three cycles of freezing, 5, 10, and 10 minutes ...tip of the cryoprobe ... See full document

... incidence of admission for IV antibiotics and need of blood transfusions were ...incidence of febrile neutropenia and had their cycles delayed for longer periods of time than the other ... See full document

... capability of cancer cells is one of the most important hallmarks reflecting metastatic ...regulation of cancer cell migration remains ...activities of human lung ... See full document

... number of independent variables (factors) was limited by the occurrence of the event ...vs. non-adenocarcinoma), AJCC stage (early ...level of significance was set at ... See full document

... FIGURA 2 - Comparação entre a entrada do EBV em células B e células epiteliais. As interações moleculares envolvidas são distintas; adicionalmente, em células B há formação de endossomo, enquanto que nas células ... See full document

... locations of progression ...continuation of the EGFR TKI as monotherapy for an extended period prior to more widespread systemic progression ...instances of asymptomatic radiographic progression, the ... See full document

... levels of salivary miRNAs and investigated their EC discriminatory power to our knowledge for the first time ...significant microRNAs and EC are needed in our future ...levels of salivary miRNAs were ... See full document

... result of increased cytotoxicity, but rather were mediated through immunological ...stimulator of T-Cells and has been used as a tumor vaccine in a variety of tumor types [21,33] Chemotherapy induced ... See full document

... binding of methionine to its corresponding tRNA. Increased activity of this enzyme has been reported in human colon cancer ...induction of MARS expression was shown in breast cancer ... See full document

... proximity of the +61G locus to a region involved in EGF gene ...Multidisciplinary Cancer Congress, in Stockholm, the association between EGF+61A/G polymorphisms and the risk of ... See full document

... significance of p-AKT expression has been examined in many cancers, although evidence is still ...expression of PTEN significantly prognosis in this patients. In renal cell carcinoma, p-AKT was ... See full document

... effect of Bmi1 ablation on lung tumor initiation in the BXB11 background as the life time of these mice matched that of Bmi1 knock out ...areas of the lung occupied by tumor ... See full document

... response of first-line chemotherapy (D) are independent prognostic factors for female patients with advanced non-small cell lung ... See full document

... effect of chemotherapy on the physical condition of patients with advanced lung ...with non-small cell lung cancer (in stages IIIB and IV) and Eastern Cooperative ... See full document