[PDF] Top 20 Development of and access to products for neglected diseases.

... in Development Factsheets for HIV/ AIDS, infectious disease, and biotechnology; International Federation of Pharmaceutical Manufacturers and Associations, ‘‘Pharmaceutical Industry R&D for ... See full document

... believed to be similar ...production and maintenance. Despite this massive expenditure, each of the 11 nuclear weapons states, with the possible exception of the ...rates of ... See full document

... the development and clinical trials of a safe and effective vaccine against dengue are encouraging ...One of these issues is the capacity of the poor who live in endemic areas ... See full document

... one of the pillars of the Brazil's Without Extreme Poverty Plan (Plano Brasil Sem Miséria) of the Federal Government, which aims to reduce the burden of disease in elimination by ... See full document

... Failure to address this collective burden of disease, now that an integrated approach seems feasible, will result in it moving steadily up the ranking into the top three once the impact of current ... See full document

... fever and leprosy are present over almost the entire Brazilian ...90% of malaria cases occur in the Northern region of the country, and lymphatic filariasis and onchocerciasis occur in ... See full document

... treatment of many NDs imposes financial charges and therefore there is little incentive on the private market to develop new treatments, being exactly one fundamental problem as induce pharmaceutical ... See full document

... malaria, and other diseases,” the preliminary SDGs outlined at Rio+20 do not list specific ...major neglected tropical diseases (NTDs) to a significant adverse impact on both human ... See full document

... US and UK Governments increase funding for integrated NTD control, there is an urgent need to also increase significantly R&D efforts devel- oped by product development partner- ships and ... See full document

... TROPICAL DISEASES: A NEW ERA OF CHALLENGES AND ...aspects of science and technology with special emphasis on the field of Chemistry and its contributions toward a more ... See full document

... tropical diseases (NTDs) exist and persist for social and economic reasons that enable the vectors and pathogens to take advantage of changes in the behavioral and ... See full document

... Infectious diseases disproportionately affect the health of populations living in low- and mid- dle-income ...addition to the most prevalent diseases, malaria, tuberculosis (TB), ... See full document

... summary of the major chronic and debilitating parasitic helminth infections affecting the eight South China Sea nations, based on the latest World Health Orga- nization (WHO) preventive chemotherapy ... See full document

... Scientific and technological breakthroughs have compelled the current players in drug discovery to increasingly incorporate knowledge-based ...attached to the recent advances in medicinal chemistry, ... See full document

... factors and NTD-induced human health outcomes, taking into account multiple pathways and interactions, should be seen in a broader spatial, socio-economic and cultural ...characteristics and ... See full document

... America and the Caribbean (LAC) over 210 million people (> 38%) live below the poverty line, and most suffer from a series of neglected diseases (NDs) also referred to as ... See full document

... extent to which a person views an innovation as offering an advantage over previous ways of performing the same task (Roger, 1983; Agarwal & Prasad, ...customers to access their banking ... See full document

... essential to identify and monitor rare or uncommon adverse events, in addition to other issues related with ...lack of definition of a biosimilar nomenclature. The use of the ... See full document

... the access to medicines with representative sample of the population living in the urban area of the ive regions of Brazil, allowing the generalization of results for the ... See full document

... binding to cytotoxic oligomers (Fig ...set of chaperones can be ...abundance of cytotoxic oligomers, chaperone F is the most suitable for arresting the former, forming fibers and thus ... See full document