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[PDF] Top 20 Development of a VLP-based HCV vaccine candidate

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Development of a VLP-based HCV vaccine candidate

Development of a VLP-based HCV vaccine candidate

... number of particles can be isolated from transduced HuH-7 and HEK293 cells supernatants, suggesting that both cells have similar productivities (data not ...presence of HCV antigens in these ... See full document

52

A novel live-attenuated vaccine candidate for mayaro Fever.

A novel live-attenuated vaccine candidate for mayaro Fever.

... All of these approaches emphasize safety but have significant drawbacks including a multiple dose requirement for efficacy, short-lived immunogenicity necessitating boosters, challenging delivery (DNA via ... See full document

9

Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.

Generation and Characterization of Live Attenuated Influenza A(H7N9) Candidate Vaccine Virus Based on Russian Donor of Attenuation.

... virus vaccine [22, 23]. In all studies either several doses of administration or various adjuvants were required for complete ...protection of ferrets from homol- ogous wild-type (wt) A/Anhui/1/2013 ... See full document

16

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge.

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge.

... results of malaria vaccine development research) from the pre-erythrocytic, blood, and sexual stages of the parasite in a small number of recombinant proteins, we selected 10 antigens ... See full document

20

Schistosomiasis Vaccine Development: Progress and Prospects

Schistosomiasis Vaccine Development: Progress and Prospects

... promoting vaccine candidates could achieve tan- gible results already in the short ...ing of the US National Institute of Allergy and In- fectious Diseases (NIAID), the Commission of European ... See full document

8

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions.

... lack of knowledge about the molecular mechanisms of merozoite inva- sion and antimalarial immunity, relatively few ...target of extensive study and is a promising ...the development of ... See full document

24

Development and evaluation of a recombinant DNA vaccine candidate expressing porcine circovirus 2 structural protein

Development and evaluation of a recombinant DNA vaccine candidate expressing porcine circovirus 2 structural protein

... Amplification of PCV2 structural ...amplification. Based on the genomic sequence of PCV2 (GenBank Accession ...U of Taq DNA polymerase (Invitrogen, USA), 200mM of each dNTP, ...0.5mM ... See full document

7

Characterization of S3Pvac Anti-Cysticercosis Vaccine Components: Implications for the Development of an Anti-Cestodiasis Vaccine

Characterization of S3Pvac Anti-Cysticercosis Vaccine Components: Implications for the Development of an Anti-Cestodiasis Vaccine

... anti-cysticercosis vaccine, composed of three peptides of 8 (KETc12), 12 (KETc1), and 18 amino acids (GK1) [16,17,27], was first identified in a ...two of these peptides, KETc1 and GK1, are ... See full document

12

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA.

... obtain VLP-display of heterologous antigenic epitopes whereas cross-linking chemistry has been employed to facilitate coupling of more complex antigens to pre-assembled ...case of the PM ... See full document

16

Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellin.

Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellin.

... the development of recombinant vaccines against various pathogens of viral and bacterial ...protein of Gram-negative bacteria, flagellin exhibits strong adjuvant properties when administered ... See full document

22

Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis

Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis

... the candidate vaccine for cutaneous leishmaniasis, which was developed by Mayrink et ...use of thimerosal in humans has been banned due to its mercury ...standardization of phenol as a new ... See full document

6

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children.

Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children.

... occurrence of SAEs from the time of first vaccination until 10 months post Dose ...days of vaccination had to be reported as ...occurrence of unsolicited AEs after each vaccination over a 30 ... See full document

11

Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis

Comparative evaluation of phenol and thimerosal as preservatives for a candidate vaccine against American cutaneous leishmaniasis

... ability of a candidate vaccine, preserved by phenol, to induce immunity against ...the candidate vaccine group, but this evidence of immunogenicity induced by the ... See full document

6

Operating characteristics of turbine mixers based on the analysis of power demand of the mixer’s drive

Operating characteristics of turbine mixers based on the analysis of power demand of the mixer’s drive

... blending of silica sand, bentonite, coal dust (or mixture) and ...purpose of mixing is to homogenise the mixture and ensure that the rebonding agent should be uniformly distributed over the ...number ... See full document

4

Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients

Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients

... clearance of hepatitis C virus (HCV) have been primarily studied in regions where the infection is ...Results of prior studies have been extrapolated to populations with low en- demicity, such as ... See full document

5

Development of a Multivalent Subunit Vaccine against Tularemia Using Tobacco Mosaic Virus (TMV) Based Delivery System.

Development of a Multivalent Subunit Vaccine against Tularemia Using Tobacco Mosaic Virus (TMV) Based Delivery System.

... discovery of F. tularensis, three broad approaches comprising of killed whole cell, live attenuated and subunit vaccines have been employed for vaccine devel- opment, but none of these have ... See full document

22

Development of Graphene Based Supercapacitors

Development of Graphene Based Supercapacitors

... reduction of GO was obtained with success. Of the three parameters studied, two show no necessity of fine tuning and represent negligible differences between samples in the range ...variations ... See full document

51

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens.

Impact of the RTS,S malaria vaccine candidate on naturally acquired antibody responses to multiple asexual blood stage antigens.

... cultures of the R29 line were cryopreserved and thawed for each assay ...well of 1% BSA/PBS and left overnight at 4 u ...L of erythrocyte suspension was added to each ...L of serum, was added ... See full document

9

Some issues in vaccination scene in India

Some issues in vaccination scene in India

... component vaccine is the fight. The manufacturers of both the type are claiming safety and efficiency of their respective vaccine type and criticizing the opposite ... See full document

2

Delayed-type hypersensitivity in human volunteers immunized with a candidate leprosy vaccine

Delayed-type hypersensitivity in human volunteers immunized with a candidate leprosy vaccine

... We report here the results of a study carried out under the IMMLEP program that examines the DTH response among human volunteers in Norway who were immunized with thi[r] ... See full document

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