[PDF] Top 20 Differential expression of cadherins in bladder cancer: role in epithelial-mesenchymal transition

... 4ºC in order to obtain the DNA ...55ºC in agitation until DNA´s digestion was ...DNA. In order for the DNA precipitation to take place, absolute ethanol (Merck, Germany) was added to it, in a ... See full document

... essential role in metastasis [27]. In a search for microRNAs that negatively regulated chemotaxis and metastasis, eight pairs of breast cancer samples and matched adjacent normal ... See full document

... increased expression in TNBC tumors and may account for the aggressiveness of these ...significant role in many signaling pathways including those that are involved in ... See full document

... gene expression by binding to partially complementary sequences in target mRNAs to induce mRNA decay, translational repression or both 1 ...hundreds of mRNAs, sometimes having a strong effect but ... See full document

... demonstrated in many cases that growth factor signaling pathways mediating the EMT process might also contribute to anoikis resistance ...[37,38]. In the present study, we proved that the EGFR/PI3K/Akt ... See full document

... breast cancer (IBC) is the most insidious form of locally advanced breast cancer; about a third of patients have distant metastasis at initial ...factors in the tumor microenvironment ... See full document

... array of mitogenic, pro-invasive, pro-angiogenic, and pro-metastatic genes ...ability of macrophages to phagocyte and present antigens to T cells, reducing their pro-inflammatory capacity ...which ... See full document

... participates in neuron communication, as it undergoes a conformational change upon depolarization in the synaptic junctional adhesion in the central nervous system (Tanaka et ...adhesion of ... See full document

... stage of the ...glycans in bladder ...STn expression is more associated with muscle invasive than non-muscle invasive disease in a larger patient set, suggesting that sialylation plays ... See full document

... cause of mortality in lung cancer ...involved in embryogenesis that may be reactivated in cancers promoting both malignant conversion and cancer progression through an ... See full document

... member of the polycomb group protein family ...self-renewal of both normal and cancer stem cells, which is overexpressed in various tu- mors, such as breast cancer, lung cancer, ... See full document

... the expression of TrkB in solid cancers [6–8], this is the first study to address the function of TrkB in human ...expressed in human endometrium, and its expression may ... See full document

... EMT in cancer cells including those from HCC [3,5,16], we firstly analyzed whether p53 has a functional role on TGF-b- and PI3K/AKT-induced EMT in PVTT-1 ...phenotype in terms of ... See full document

... PHD3 expression could revert MiaPaca2 cells from their mesenchymal-like morphology back to a more epithelial phenotype, we created a stable PHD3-Wt-overexpress- ing MiaPaca2 cell ...levels of ... See full document

... range of experimental models are suggestive of an important role for β-catenin in pancreatic cancer ...suppressor of G2 allele of Skp1 ...is in- volved in ... See full document

... The epithelial-to-mesenchymal transition (EMT) is a highly conserved physiological program involved in development and tissue repair; however, its aberrant activation has been implicated ... See full document

... the role of KLF4 in ovarian cancer cells using lentiviral vector mediated inducible ...downregulated in ovarian cancers compared to controls and that KLF4 did not affect cell ... See full document

... the role of CD44 in cell adhesion and migration, the alteration of expression found in this study might reflect alterations in cell ...crucial role in ECM ... See full document

... mRNA expression is decreased in human bladder urothelial cancer Relative Elf5 levels in tumor tissue from 50 UC patients were determined by qRT-PCR span- ning 90 bp, normalized by ... See full document

... IDO expression and Akt/pAkt signaling path- way ...micrograms of total protein were denatured and loaded on a 12% sodium dodecyl sulfate (SDS)-polyacryl- amide electrophoresis gel and then transferred to a ... See full document