[PDF] Top 20 Drosophila duplication hotspots are associated with late-replicating regions of the genome.
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Drosophila duplication hotspots are associated with late-replicating regions of the genome.
... extremes of the phenotypic spectrum of newly arising mutations: they can have severe deleterious effects ...variety of diseases) but can also be highly advantageous. The phenotypic ... See full document
12
CTCF genomic binding sites in Drosophila and the organisation of the bithorax complex.
... elements are proposed to play an important role in the regulation of transcription by preventing inappropriate enhancer/promoter ...interaction. The zinc-finger protein CTCF is well studied in ... See full document
12
Deep analysis of wild Vitis flower transcriptome reveals unexplored genome regions associated with sex specification
... interaction with LEAFY and SEPALLATA3 regulate the activation of AP3 and AG during flower devel- opment (Wagner and Meyerowitz ...activator of WUS and required for the maintenance ... See full document
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How hot are drosophila hotspots? examining recombination rate variation and associations with nucleotide diversity, divergence, and maternal age in Drosophila pseudoobscura.
... amount of variation in crossover rate across the genomes of many species, and such variation in mammalian and yeast genomes is concentrated to ,5 kb regions of highly elevated ... See full document
6
Late replicating domains are highly recombining in females but have low male recombination rates: implications for isochore evolution.
... autosomal regions differ in the rate of evolution of putatively neutral sites ...replicate the same number of times in any given germline, this heterogeneity can not be accounted ... See full document
11
Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
... support the BIN1 locus which was recently identified in an independent study ...reached genome-wide significance level and there are no known overlaps between the sample ...in the other ... See full document
9
Late replication domains are evolutionary conserved in the Drosophila genome.
... Maintenance of gene order conservation in underreplicated and late-replicating regions may also be explained by the presence of intergenic regions encompassing particular ... See full document
12
Regulatory hotspots in the malaria parasite genome dictate transcriptional variation.
... feature of the regulatory architecture is the prominent role of CNVs in directing transcription variation, particularly from regions previously associated with drug ... See full document
12
Law, responsibility, and the brain.
... possibility of being “not guilty by reason of insanity” can be traced back to the well-known M’Naghten case in ...kill the British Prime Minister, Daniel M’Naghten mistakenly killed the ... See full document
8
Multiple-integrations of HPV16 genome and altered transcription of viral oncogenes and cellular genes are associated with the development of cervical cancer.
... Integration of HPV genome into host chromosomes represents an early clonal event to provide an additional selective advantage for the expansion of the ...by the APOT assay ... See full document
9
SHORT COMMUNICATION The invasive spotted-wing Drosophila (Diptera, Drosophilidae) has been found in the city of São Paulo (Brazil)
... species of fruits were bought by one of us (LM) at a grocery store located at avenida Corifeu de Azevedo Marques 1000 ...state of Santa Catarina, and Vacaria (100 g), state of Rio Grande do ... See full document
5
Metastable differentially methylated regions within Arabidopsis inbred populations are associated with modified expression of non-coding transcripts.
... for the MRD1 transcript encode peptides of 5 amino acids (ORF1), 32 amino acids (ORF2) and 120 amino acids (ORF3) (Figure ...using the protein sequence of ORF3 did not identify any conserved ... See full document
11
Structural stability of the high-aluminium zinc alloys modified with Ti addition
... microstructure of the binary ZnAl26 alloy poured into a sand mould is shown in ...shows the microstructure obtained in the same conditions, but after addition of the ...into ... See full document
6
On The Impact Of Pressure Drop On Human Body With Mathematical Models
... for the impact of pressure drop on the human body has been investigated in the present ...studies. The studies has been aimed at personnel (army and mountaineer) who would be prone for ... See full document
3
Contrasted patterns of crossover and non-crossover at Arabidopsis thaliana meiotic recombination hotspots.
... [9]. The CO to NCO ratio is also extremely variable in human and mice from more than 12:1 to 1:10 ...at the bronze loci, the CO to NCO ratio varies from 30:1 to 1:6 depending on the presence ... See full document
15
Novel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses.
... saline). The cells were then resuspended in RIPA buffer (50 mM Tris-HCl, pH ...cocktail of protease inhibitors (Roche) and RNase inhibitor (Takara, Japan) and lysed by 3 freeze–thaw ...materials, the ... See full document
11
Selection of the temperature of casting the bronzes to plaster moulds
... view of the drop of the solidification bronze on plaster mould and the fragments of plaster mould from the side of the contact with the melted ... See full document
6
Identifying Human Genome-Wide CNV, LOH and UPD by Targeted Sequencing of Selected Regions.
... concerns the detection of breaking points, or the exact CNV transition ...each of our probes is located either entirely out of a CNV or entirely ...sequence the genomic ... See full document
18
Extensive divergence of transcription factor binding in Drosophila embryos with highly conserved gene expression.
... both the genomic causes and the consequences on gene expression of TF binding ...that the genomic binding of A-P factors has changed extensively along the Drosophila tree ... See full document
18
Caprin controls follicle stem cell fate in the Drosophila ovary.
... in the GSC lineage, FSC lineage, and terminal filament compared to the cap cells and escort cells, where CAPR is barely detectable (Figure 3 and data not ...used the heat-shock-induced FLP/FRT method ... See full document
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